Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Craig A. Mullen"'
Autor:
Naveen Pemmaraju, Branko Cuglievan, Joseph Lasky, Albert Kheradpour, Nobuko Hijiya, Anthony S. Stein, Soheil Meshinchi, Craig A. Mullen, Emanuele Angelucci, Luciana Vinti, Tariq I. Mughal, Anna B. Pawlowska
Publikováno v:
eJHaem, Vol 5, Iss 1, Pp 61-69 (2024)
Abstract Blastic plasmacytoid dendritic cell neoplasm (BPDCN) predominantly occurs in adults ≥60 years old; 10–20% of cases are pediatric or adolescent/young adult (AYA) patients. Tagraxofusp (TAG, Elzonris®) is the only approved treatment for B
Externí odkaz:
https://doaj.org/article/f0c19f1aedd446e39c2ceaabeb4efd0f
Publikováno v:
Pediatrics In Review. 44:96-99
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88966 (2014)
Stem cell antigen-1 (Ly6a/Sca-1) is a gene that is expressed in activated lymphocytes, hematopoietic stem cells and stem cells of a variety of tissues in mice. Despite decades of study its functions remain poorly defined. These studies explored the i
Externí odkaz:
https://doaj.org/article/fb9127f1e3d541a6b8c847dd092fed1c
Autor:
Elena Edwards, Michelle Qiu, Sonakshi Sharma, Leti Nunez, Dominic Schenone, Jeffrey R. Andolina, Thomas J. Fountaine, Brooks Rademacher, Craig A. Mullen
Publikováno v:
Anticancer research. 41(6)
Background/aim This study explored the mechanisms of the allogeneic graft versus leukemia effect in acute lymphoblastic leukemia (ALL) cells by examining whether they change gene expression in the post-transplant environment containing cytokines and
Autor:
Nancy S Green, Katherine L Ender, Farzana Pashankar, Catherine Driscoll, Patricia J Giardina, Craig A Mullen, Lorraine N Clark, Deepa Manwani, Jennifer Crotty, Sergey Kisselev, Kathleen A Neville, Carolyn Hoppe, Sandra Barral
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55709 (2013)
Fetal hemoglobin level is a heritable complex trait that strongly correlates swith the clinical severity of sickle cell disease. Only few genetic loci have been identified as robustly associated with fetal hemoglobin in patients with sickle cell dise
Externí odkaz:
https://doaj.org/article/b92ea4c772dc4035bd0462f3b0f400f6
Autor:
Craig A. Mullen, Kristy S. Pahl
Publikováno v:
Experimental Biology and Medicine. 241:745-758
Sickle cell disease is a severe hemoglobinopathy caused by mutations in the beta globin genes. The disorder has protean manifestations and leads to severe morbidity and early mortality. Acute chest syndrome (ACS) is a common complication and in the U
Autor:
Leti Nunez, Sana Usmani, Olena Tkachenko, Jessica C. Shand, Urmila Sivagnanalingam, Craig A. Mullen
Publikováno v:
Oncology Letters
The present report describes work examining the manner in which nonmalignant bone marrow stromal cells prevent acute lymphoblastic leukemia (ALL) cell death. The initial focus was on the role of stromal cell-derived C-X-C motif chemokine 12 (CXCL12).
Publikováno v:
CHASE
Given the increasing availability and accessibility of mobile devices, there is enormous potential to transform how healthcare is administered through the creation of highly customized smartphone-based applications for effective medical condition man
Publikováno v:
CHASE
Given the increasing availability and accessibility of mobile devices, there is enormous potential to transform how healthcare is administered through the creation of highly customized smartphone-based applications for effective medical condition man
Autor:
Nerissa Velazco, Andrew D. Racine, Farzana Pashankar, M. Catherine Driscoll, Patricia J. Giardina, Rebecca Trachtman, Suzette O. Oyeku, Craig A. Mullen, Nancy S. Green, Hillel W. Cohen
Publikováno v:
Pediatric Blood & Cancer. 60:653-658
Background Hydroxyurea (HU) is highly effective treatment for Sickle Cell Disease (SCD). While pediatric use of HU is accepted clinical practice, barriers to use may impede its potential benefit.