Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Craig A. Hokanson"'
Autor:
Caterina Riillo, Nicoletta Polerà, Maria Teresa Di Martino, Giada Juli, Craig A. Hokanson, Tatjana Odineca, Stefania Signorelli, Katia Grillone, Serena Ascrizzi, Antonia Mancuso, Nicoletta Staropoli, Basilio Caparello, Maria Cerra, Giuseppe Nisticò, Pierosandro Tagliaferri, Roberto Crea, Daniele Caracciolo, Pierfrancesco Tassone
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Pronectins™ are a new class of fibronectin-3-domain 14th-derived (14Fn3) antibody mimics that can be engineered as bispecific T cell engager (BTCE) to redirect immune effector cells against cancer. We describe here the in vitro
Externí odkaz:
https://doaj.org/article/0787a02d83dd4274bb7935635c4bf039
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3184 (2022)
A highly specific AXL-receptor targeted family of non-immunoglobulin, single domain protein binders (Pronectins™) have been isolated from three (3) synthetic libraries that employ the human scaffold of the 14th domain of Fibronectin III (14FN3) and
Externí odkaz:
https://doaj.org/article/f9beccc674ee4ecda081e0285a352de3
Autor:
Tassone, Nicoletta Polerà, Antonia Mancuso, Caterina Riillo, Daniele Caracciolo, Stefania Signorelli, Katia Grillone, Serena Ascrizzi, Craig A. Hokanson, Francesco Conforti, Nicoletta Staropoli, Luigia Gervasi, Maria Teresa Di Martino, Mariamena Arbitrio, Giuseppe Nisticò, Roberto Crea, Pierosandro Tagliaferri, Giada Juli, Pierfrancesco
Publikováno v:
Cancers; Volume 15; Issue 6; Pages: 1647
Sarcomas are heterogeneous malignancies with limited therapeutic options and a poor prognosis. We developed an innovative immunotherapeutic agent, a first-in-class Pronectin™-based Bispecific T-Cell Engager (pAXL×CD3ε), for the targeting of AXL,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::e68a37531bf3cb17bdfe376167ffa022
Autor:
Nicoletta Polerà, Antonia Mancuso, Caterina Riillo, Daniele Caracciolo, Stefania Signorelli, Katia Grillone, Serena Ascrizzi, Craig A. Hokanson, Francesco Conforti, Nicoletta Staropoli, Luigia Gervasi, Maria Teresa Di Martino, Mariamena Arbitrio, Giuseppe Nisticò, Roberto Crea, Pierosandro Tagliaferri, Giada Juli, Pierfrancesco Tassone
Publikováno v:
Cancers. 15:1647
Sarcomas are heterogeneous malignancies with limited therapeutic options and a poor prognosis. We developed an innovative immunotherapeutic agent, a first-in-class Pronectin™-based Bispecific T-Cell Engager (pAXL×CD3ε), for the targeting of AXL,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e570facbe524e0b22382fcca7e68205c
https://doi.org/10.3390/cancers15061647
https://doi.org/10.3390/cancers15061647
Autor:
Stephen P. Mayfield, Craig A. Behnke, Machiko Muto, Roberto Crea, Philip A. Lee, Craig A. Hokanson, Beth A. Rasala, Rosa M.F. Cardoso, Peter B. Kirk, Michael Mendez, Michal Jager
Publikováno v:
Plant Biotechnology Journal. 8:719-733
Recombinant proteins are widely used today in many industries, including the biopharmaceutical industry, and can be expressed in bacteria, yeasts, mammalian and insect cell cultures, or in transgenic plants and animals. In addition, transgenic algae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a37d1dc1b658969fdc810e360b6105dd
https://doi.org/10.1111/j.1467-7652.2010.00503.x
https://doi.org/10.1111/j.1467-7652.2010.00503.x
Autor:
Brian A. Donahue, Michael Mendez, Emery G. Dora, Craig A. Hokanson, Mitchell H. Finer, Marianne Rivkin
Publikováno v:
Human Gene Therapy. 14:329-339
Adenoviral vectors are widely used to express transgenes in vitro and in vivo. A major obstacle to the generation of adenoviral vectors is the manipulation of the large (35 kb) adenoviral genome. We developed a hybrid yeast-bacteria cloning system fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9b6644157631f22ac04f6777006f27
https://doi.org/10.1089/104303403321208934
https://doi.org/10.1089/104303403321208934
Autor:
Olivier Danos, Steven Jungles, Jennifer L. Davis, Paul R. Gross, Craig A. Hokanson, Lawrence K. Cohen, S. Kaye Spratt, Rochelle Witt
Publikováno v:
Human Gene Therapy. 8:1459-1467
The goal of this work was to determine whether a stable 293 amphotropic packaging line, which we have designated 293-SPA, is useful for the production of high-titer stable virus by comparison to the murine psiCRIP line. Here, we report our unexpected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4c3c23e7bf2783367b05f6ae9eb420
https://doi.org/10.1089/hum.1997.8.12-1459
https://doi.org/10.1089/hum.1997.8.12-1459
Autor:
Roberto Crea, Craig A. Behnke, William J. Coleman, Guido Cappuccilli, Craig A. Hokanson, Michael Mendez, Tatjana Odineca, Marino Bozic
Publikováno v:
Protein engineering, designselection : PEDS. 24(8)
A new directed evolution method was used to enhance the thermostability of the wild-type GH11 xylanase 2 (known as BD-11) from Hypocrea jecorina (Trichoderma reesei). Both Look-Through Mutagenesis (LTM™), which is a method for rapidly screening sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a2cb9ec88e2d68946a843d9bd1f1e1
https://pubmed.ncbi.nlm.nih.gov/21708791
https://pubmed.ncbi.nlm.nih.gov/21708791
Ferroportin is a multi-pass membrane protein that serves as an iron exporter in many vertebrate cell types. Ferroportin-mediated iron export is controlled by the hormone hepcidin, which binds ferroportin, causing its internalization and degradation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb1661d0db50e7e5f874b47a077cd52
https://resolver.caltech.edu/CaltechAUTHORS:20090422-143224842
https://resolver.caltech.edu/CaltechAUTHORS:20090422-143224842
