Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Craig A Emter"'
Autor:
Taylor J. Kelty, Chris L. Taylor, Nicole E. Wieschhaus, Pamela K. Thorne, Amira R. Amin, Christina M. Mueller, T. Dylan Olver, Darla L. Tharp, Craig A. Emter, Alexander W. Caulk, R. Scott Rector
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Diet-induced obesity is implicated in the development of a variety of neurodegenerative disorders. Concurrently, the loss of mitochondrial Complex I protein or function is emerging as a key phenotype across an array of neurodegenerative disorders. Th
Externí odkaz:
https://doaj.org/article/77e17acae05643758ef8bc4dc5d12d33
Autor:
Mohamed Zaid, Lorenzo Sala, Laurel Despins, David Heise, Mihail Popescu, Marjorie Skubic, Salman Ahmad, Craig A. Emter, Virginia H. Huxley, Giovanna Guidoboni
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
In this study, anatomical and functional differences between men and women in their cardiovascular systems and how these differences manifest in blood circulation are theoretically and experimentally investigated. A validated mathematical model of th
Externí odkaz:
https://doaj.org/article/80c71233041b4a17a839c501e193cb09
Autor:
Mohamed Zaid, Lorenzo Sala, Jan R. Ivey, Darla L. Tharp, Christina M. Mueller, Pamela K. Thorne, Shannon C. Kelly, Kleiton Augusto Santos Silva, Amira R. Amin, Pilar Ruiz-Lozano, Michael S. Kapiloff, Laurel Despins, Mihail Popescu, James Keller, Marjorie Skubic, Salman Ahmad, Craig A. Emter, Giovanna Guidoboni
Publikováno v:
Frontiers in Medical Technology, Vol 4 (2022)
Left ventricular (LV) catheterization provides LV pressure-volume (P-V) loops and it represents the gold standard for cardiac function monitoring. This technique, however, is invasive and this limits its applicability in clinical and in-home settings
Externí odkaz:
https://doaj.org/article/c8d1c5d427c24c598af79f22e9e6a80e
Autor:
T. Dylan Olver, PhD, Jenna C. Edwards, BS, Thomas J. Jurrissen, BS, Adam B. Veteto, MS, John L. Jones, MS, Chen Gao, BS, Christoph Rau, PhD, Chad M. Warren, MS, Paula J. Klutho, PhD, Linda Alex, PhD, Stephanie C. Ferreira-Nichols, BS, Jan R. Ivey, BS, Pamela K. Thorne, MS, Kerry S. McDonald, PhD, Maike Krenz, MD, Christopher P. Baines, PhD, R. John Solaro, PhD, Yibin Wang, PhD, David A. Ford, PhD, Timothy L. Domeier, PhD, Jaume Padilla, PhD, R. Scott Rector, PhD, Craig A. Emter, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 404-421 (2019)
Summary: The development of new treatments for heart failure lack animal models that encompass the increasingly heterogeneous disease profile of this patient population. This report provides evidence supporting the hypothesis that Western Diet−fed,
Externí odkaz:
https://doaj.org/article/234f0de86b414fc8be6239d78aedf7cf
Autor:
Bradley J. Baranowski, Matti D. Allen, Jennifer N.K. Nyarko, R. Scott Rector, Jaume Padilla, Darrell D. Mousseau, Christoph D. Rau, Yibin Wang, M. Harold Laughlin, Craig A. Emter, Rebecca E.K. MacPherson, T. Dylan Olver
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Individuals with heart failure (HF) frequently present with comorbidities, including obesity, insulin resistance, hypertension, and dyslipidemia. Many patients with HF experience cardiogenic dementia, yet the pathophysiology of this disease remains p
Externí odkaz:
https://doaj.org/article/c9b519b32daa4129a242729f4019a246
Autor:
Camila Manrique-Acevedo, Rogerio N. Soares, James A. Smith, Lauren K. Park, Katherine Burr, Francisco I. Ramirez-Perez, Neil J. McMillan, Larissa Ferreira-Santos, Neekun Sharma, T. Dylan Olver, Craig A. Emter, Elizabeth J. Parks, Jacqueline K. Limberg, Luis A. Martinez-Lemus, Jaume Padilla
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R293-R304
Vascular insulin resistance, a major characteristic of obesity and type 2 diabetes (T2D), manifests with blunting of insulin-induced vasodilation. Although there is evidence that females are more whole body insulin sensitive than males in the healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6cc608667930643d3fee84de17e81c
https://doi.org/10.1152/ajpregu.00249.2022
https://doi.org/10.1152/ajpregu.00249.2022
Publikováno v:
Journal of Applied Physiology. 134:482-489
This retrospective analysis evaluated the impact of exercise, sex, and diet on ACE2 and TMPRSS2 mRNA levels in preclinical swine heart failure models. Unlike normal exercise intensities, exercise training of an intensity tolerable to a patient with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f8556a54653c8a6ad4741815d1f3cc
https://doi.org/10.1152/japplphysiol.00736.2022
https://doi.org/10.1152/japplphysiol.00736.2022
Autor:
Jinliang Li, Shannon C. Kelly, Jan R. Ivey, Pamela K. Thorne, Kelly P. Yamada, Tadao Aikawa, Renata Mazurek, James R. Turk, Kleiton Augusto Santos Silva, Amira R. Amin, Darla L. Tharp, Christina M. Mueller, Hrishikesh Thakur, Emily V. Leary, Timothy L. Domeier, R. Scott Rector, Kenneth Fish, Federico Cividini, Kiyotake Ishikawa, Craig A. Emter, Michael S. Kapiloff
Publikováno v:
Physiol Genomics
Limited reports exist regarding adeno-associated virus (AAV) biodistribution in swine. This study assessed biodistribution following antegrade intracoronary and intravenous delivery of two self-complementary serotype 9 AAV (AAV9sc) biologics designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0e3ddf76605f364784356e1691fe34
https://doi.org/10.1152/physiolgenomics.00032.2022
https://doi.org/10.1152/physiolgenomics.00032.2022
Autor:
Grant C. Hayward, Paul J. LeBlanc, Craig A. Emter, Jennifer N. K. Nyarko, Darrell D. Mousseau, Rebecca E. K. MacPherson, T. Dylan Olver
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Post-menopausal women with heart failure (HF) frequently exhibit cardiogenic dementia. Using a pre-clinical swine model of post-menopausal HF, we recently demonstrated that experimental menopause (ovariectomy; OVX) and HF (6-month cardiac pressure ov
Externí odkaz:
https://doaj.org/article/0292b002735c467fa66638e7c47e6212
Autor:
T. Dylan Olver, Jessica A. Hiemstra, Jenna C. Edwards, Todd R. Schachtman, Cheryl M. Heesch, Paul J. Fadel, M. Harold Laughlin, Craig A. Emter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundPostmenopausal women represent the largest cohort of patients with heart failure with preserved ejection fraction, and vascular dementia represents the most common form of dementia in patients with heart failure with preserved ejection frac
Externí odkaz:
https://doaj.org/article/24df2e1448ec451aa6136ec095e209fd