Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Craig A Elmets"'
Autor:
Hui Li, Erica Burgueño-Bucio, Shin Xu, Shaonli Das, Roxana Olguin-Alor, Craig A Elmets, Mohammad Athar, Chander Raman, Gloria Soldevila, Hui Xu
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222301 (2019)
The role of CD5 as a regulator of T cell signaling and tolerance is well recognized. Recent data show expression of CD5 on different subtypes of human dendritic cells, however its functional relevance in modulating DC mediated responses remains poorl
Externí odkaz:
https://doaj.org/article/b1fc201649804331975080665cfc33b7
Autor:
Lizhi Wu, Sandeep C Chaudhary, Venkatram R Atigadda, Olga V Belyaeva, Steven R Harville, Craig A Elmets, Donald D Muccio, Mohammad Athar, Natalia Y Kedishvili
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153556 (2016)
UAB30 is an RXR selective agonist that has been shown to have potential cancer chemopreventive properties. Due to high efficacy and low toxicity, it is currently being evaluated in human Phase I clinical trials by the National Cancer Institute. While
Externí odkaz:
https://doaj.org/article/09ed2b589b2e4e7abd2ce7f9805ba18f
Autor:
Harish Chandra Pal, Samriti Sharma, Leah Ray Strickland, Santosh K Katiyar, Mary E Ballestas, Mohammad Athar, Craig A Elmets, Farrukh Afaq
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86338 (2014)
Malignant melanoma is responsible for approximately 75% of skin cancer-related deaths. BRAF plays an important role in regulating the mitogen-activated protein kinase (MAPK) signaling cascade in melanoma with activating mutations in the serine/threon
Externí odkaz:
https://doaj.org/article/9f05bec9c95d426da2742364f34c0b66
Autor:
Harish Chandra Pal, Samriti Sharma, Leah Ray Strickland, Jyoti Agarwal, Mohammad Athar, Craig A Elmets, Farrukh Afaq
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77270 (2013)
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor 2 (VEGFR2) have emerged as two effective clinical targets for non-small-cell lung cancer (NSCLC). In the present study, we found that delphinidin, an anthocyanidi
Externí odkaz:
https://doaj.org/article/64fbc4f94db2424fad16156b9a55484b
Autor:
Aadithya Arumugam, Zhiping Weng, Sarang S Talwelkar, Sandeep C Chaudhary, Levy Kopelovich, Craig A Elmets, Farrukh Afaq, Mohammad Athar
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80076 (2013)
Non-melanoma skin cancer (NMSC) is the most common type of skin cancer in Caucasian populations. Its increasing incidence has been a major public health concern. Elevated expressions of ODC and COX-2 are associated with both murine and human NMSCs. I
Externí odkaz:
https://doaj.org/article/50d628605a334e1a845f4be5bedd92e3
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32126 (2012)
The mechanism for inflammation associated tumor development is a central issue for tumor biology and immunology and remains to be fully elucidated. Although IL-17 is implicated in association with inflammation mediated carcinogenesis, mechanisms are
Externí odkaz:
https://doaj.org/article/7f832eb0a0b6432a9c43b1629df4a31b
Autor:
Lin Jin, Mahendra P. Kashyap, Yunjia Chen, Jasim Khan, Yuanyuan Guo, Jari Q. Chen, Madison B. Lee, Zhiping Weng, Allen Oak, Prasanth Patcha, Tiffany Mayo, Rajesh Sinha, Venkatram Atigadda, Shahid M. Mukhtar, Jessy S. Deshane, Chander Raman, Carly Elston, Boni E. Elewski, Craig A. Elmets, Mohammad Athar
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106896- (2023)
Summary: Hidradenitis suppurativa (HS) is a skin disorder that causes chronic painful inflammation and hyperproliferation, often with the comorbidity of invasive keratoacanthoma (KA). Our research, employing high-resolution immunofluorescence and dat
Externí odkaz:
https://doaj.org/article/0de4db9502ab4617909eb859b7c9b5e5
Autor:
Venkatram R. Atigadda, Mahendra P. Kashyap, Zhengrong Yang, Debasish Chattopadhyay, Nathalia Melo, Rajesh Sinha, Olga V. Belyaeva, Chu-Fang Chou, Pi-Ling Chang, Natalia Y. Kedishvili, Clinton J. Grubbs, Matthew B. Renfrow, Donald D. Muccio, Craig A. Elmets, Mohammad Athar
Publikováno v:
J Med Chem
Compound 1 is a potent rexinoid that is highly effective in cancer chemoprevention but elevates serum triglycerides. In an effort to separate the lipid toxicity from the anticancer activity of 1, we synthesized four new analogs of rexinoid 1, of whic
Autor:
Mahendra Pratap, Kashyap, Jasim, Khan, Rajesh, Sinha, Lin, Jin, Venkatram, Atigadda, Jessy S, Deshane, Ayesha R, Ahmed, Ali, Kilic, Chander, Raman, M Shahid, Mukhtar, Craig A, Elmets, Mohammad, Athar
Publikováno v:
Seminars in Cell & Developmental Biology. 128:120-129
Hidradenitis suppurativa (HS) is characterized by deep-seated, highly inflamed, and painful lumps/abscesses, fistulae, and sinus tracts that grow extensively deep in the dermis and are highly immunogenic in nature. In about one-third of the HS patien
Autor:
Mohammad Athar, Habibul Ahsan, Craig A. Elmets, Jianming Wen, Zhiping Weng, Sandeep C. Chaudhary, Fugui Li, Jianmin Xu, Changzhao Li
Arsenic exposure through drinking water is a major global public health problem and is associated with an enhanced risk of various cancers including skin cancer. In human skin, arsenic induces precancerous melanosis and keratosis, which may progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef29095504adb6a52466f210a246085
https://doi.org/10.1158/1940-6207.c.6544602
https://doi.org/10.1158/1940-6207.c.6544602