Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Craig, Winstanley"'
Autor:
Kay A Ramsay, Attika Rehman, Samuel T Wardell, Lois W Martin, Scott C Bell, Wayne M Patrick, Craig Winstanley, Iain L Lamont
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285856 (2023)
Pseudomonas aeruginosa causes a wide range of severe infections. Ceftazidime, a cephalosporin, is a key antibiotic for treating infections but a significant proportion of isolates are ceftazidime-resistant. The aim of this research was to identify mu
Externí odkaz:
https://doaj.org/article/54bc854609b84c83a03edbd6886ce667
Autor:
Chowdhury M. Hasan, Sian Pottenger, Angharad E. Green, Adrienne A. Cox, Jack S. White, Trevor Jones, Craig Winstanley, Aras Kadioglu, Megan H. Wright, Daniel R. Neill, Joanne L. Fothergill
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Pseudomonas aeruginosa undergoes diversification during infection of the cystic fibrosis (CF) lung. Understanding these changes requires model systems that capture the complexity of the CF lung environment. We previously identified loss-of-function m
Externí odkaz:
https://doaj.org/article/22204499f90d4a298bfea430f8163726
Autor:
Stephen Kaye, Keri McLean, Dominic Byrne, Craig Winstanley, Daniel M Foulkes, Marta Sloniecka, Atikah S Haneef, Neil G Berry, David G Fernig
Publikováno v:
BMJ Open Ophthalmology, Vol 7, Iss Suppl 1 (2022)
Externí odkaz:
https://doaj.org/article/b5ea491a594d42a396902e0d903d5a3a
Autor:
Adrian Cazares, Matthew P. Moore, James P. J. Hall, Laura L. Wright, Macauley Grimes, Jean-Guillaume Emond-Rhéault, Pisut Pongchaikul, Pitak Santanirand, Roger C. Levesque, Joanne L. Fothergill, Craig Winstanley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The emergence of multidrug resistance (MDR) in bacteria represents a global threat to human health. Here, Cazares et al. identify a family of MDR megaplasmids carrying large arrays of antibiotic resistance genes in Pseudomonas strains from various so
Externí odkaz:
https://doaj.org/article/b3e3a6e492364cb59fec9c6d1a7c089f
Autor:
Anthony De Soyza, Philip Mawson, Adam T. Hill, Stuart Elborn, Judy M. Bradley, Charles S. Haworth, R. Andres Floto, Robert Wilson, Michael R. Loebinger, Mary Carroll, Megan Crichton, James D. Chalmers, Anita Sullivan, Jeremy Brown, John R. Hurst, Jamie Duckers, Martin Kelly, John Steer, Tim Gatheral, Paul P. Walker, Craig Winstanley, Alistair McGuire, David Denning, Richard McNally
Publikováno v:
ERJ Open Research, Vol 7, Iss 2 (2021)
Bronchiectasis has been a largely overlooked disease area in respiratory medicine. This is reflected by a shortage of large-scale studies and lack of approved therapies, in turn leading to a variation of treatment across centres. BronchUK (Bronchiect
Externí odkaz:
https://doaj.org/article/54698cb8547746ac8a06a7230fbcd6c9
Autor:
Sam Haldenby, Christina Bronowski, Charlotte Nelson, John Kenny, Carmen Martinez-Rodriguez, Roy Chaudhuri, Nicola J Williams, Ken Forbes, Norval J Strachan, Jane Pulman, Ian N Winstanley, Caroline E Corless, Tom J Humphrey, Frederick J Bolton, Sarah J O'Brien, Neil Hall, Christiane Hertz-Fowler, Craig Winstanley
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227535 (2020)
BackgroundCampylobacter jejuni is the most common bacterial cause of human infectious intestinal disease.MethodsWe genome sequenced 601 human C. jejuni isolates, obtained from two large prospective studies of infectious intestinal disease (IID1 [isol
Externí odkaz:
https://doaj.org/article/72fd2b751da34c56b4103af86ab2d938
Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa
Autor:
Laura Bricio-Moreno, Victoria H. Sheridan, Ian Goodhead, Stuart Armstrong, Janet K.L. Wong, Elaine M. Waters, Joscelyn Sarsby, Stavros Panagiotou, James Dunn, Adrita Chakraborty, Yongliang Fang, Karl E. Griswold, Craig Winstanley, Joanne L. Fothergill, Aras Kadioglu, Daniel R. Neill
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Mutations in gene pmrB are found in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Here, Bricio-Moreno et al. show in a mouse model of respiratory infection that the mutations enhance bacterial adherence to epithelial cells and resist
Externí odkaz:
https://doaj.org/article/dc57b3200e764343a7284314e6587068
Autor:
Daniel M. Foulkes, Keri McLean, Marta Sloniecka, Sophie Rustidge, Dominic P. Byrne, Atikah S. Haneef, Craig Winstanley, Neil Berry, David G. Fernig, Stephen B. Kaye
Publikováno v:
Biochemical Journal. 480:491-493
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2199dbddcdef317e2fb44260121c5d7b
https://doi.org/10.1042/bcj20220527_cor
https://doi.org/10.1042/bcj20220527_cor
Autor:
Lindsey Flanagan, Rachel R. Steen, Karinna Saxby, Mirre Klatter, Benjamin J. Aucott, Craig Winstanley, Ian J. S. Fairlamb, Jason M. Lynam, Alison Parkin, Ville-Petri Friman
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Carbon monoxide releasing molecules (CORMs) have been suggested as a new synthetic class of antimicrobials to treat bacterial infections. Here we utilized a novel EBOR-CORM-1 ([NEt4][MnBr2(CO)4]) capable of water-triggered CO-release, and tested its
Externí odkaz:
https://doaj.org/article/e44944a1cb2743daa2baa114fef7729f
Autor:
Daniel M. Foulkes, Keri McLean, Marta Sloniecka, Sophie Rustidge, Dominic P. Byrne, Atikah S. Haneef, Craig Winstanley, Neil Berry, David G. Fernig, Stephen B. Kaye
Publikováno v:
The Biochemical journal. 479(24)
The opportunistic pathogen Pseudomonas aeruginosa is one of leading causes of disability and mortality worldwide and the world health organisation has listed it with the highest priority for the need of new antimicrobial therapies. P. aeruginosa stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d346bf04e418864c60030839fd9b8600
https://pubmed.ncbi.nlm.nih.gov/36504127
https://pubmed.ncbi.nlm.nih.gov/36504127