Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Craig, Murdoch"'
Publikováno v:
Biomaterial Investigations in Dentistry, Vol 7, Iss 1, Pp 146-157 (2020)
Objectives To investigate if differences in titanium implant surface topography influence Candida albicans biofilm formation. Materials and Methods Titanium discs were prepared and characterized using a profilometer: Group A (Ra 0.15 µm, smooth), Gr
Externí odkaz:
https://doaj.org/article/95982e89ad5a4a8286a6e9c29ebef018
Publikováno v:
Frontiers in Oral Health, Vol 2 (2021)
Decades ago, the study of cancer biology was mainly focused on the tumor itself, paying little attention to the tumor microenvironment (TME). Currently, it is well recognized that the TME plays a vital role in cancer development and progression, with
Externí odkaz:
https://doaj.org/article/4779c79579ae4dc1ae02bae25336a035
Autor:
Amy L. Harding, Craig Murdoch, Simon Danby, Md Zobaer Hasan, Hirofumi Nakanishi, Tetsuo Furuno, Sirwan Hadad, Robert Turner, Helen E. Colley
Publikováno v:
JID Innovations, Vol 1, Iss 2, Pp 100011- (2021)
There are no physical or visual manifestations that define skin sensitivity or irritation; a subjective diagnosis is made on the basis of the evaluation of clinical presentations, including burning, prickling, erythema, and itching. Adverse skin reac
Externí odkaz:
https://doaj.org/article/c3b826496c984778b2a6f8ac07f8d4d0
Autor:
Sabrina Barbosa de Souza Ferreira, Gustavo Braga, Évelin Lemos Oliveira, Jéssica Bassi da Silva, Hélen Cássia Rosseto, Lidiane Vizioli de Castro Hoshino, Mauro Luciano Baesso, Wilker Caetano, Craig Murdoch, Helen Elizabeth Colley, Marcos Luciano Bruschi
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2304-2328 (2019)
Mucoadhesive nanostructured systems comprising poloxamer 407 and Carbopol 974P® have already demonstrated good mucoadhesion, as well as improved mechanical and rheological properties. Curcumin displays excellent biological activity, mainly in oral s
Externí odkaz:
https://doaj.org/article/42509663bb1b48938dafb94ccd57250a
Publikováno v:
Sensors, Vol 22, Iss 15, p 5913 (2022)
A multiscale modelling approach has been applied to the simulation of the electrical properties of oral tissue, for the purpose of informing an electrical impedance-based method of oral potential malignant disorder (OPMD) diagnosis. Finite element mo
Externí odkaz:
https://doaj.org/article/2fb55f937d7d4d7bb424773586d43c82
Autor:
Hannah West, Fiona Roberts, Paul Sweeney, Simon Walker-Samuel, Joseph Leedale, Helen Colley, Craig Murdoch, Rebecca J Shipley, Steven Webb
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254208 (2021)
Nanoparticles have the potential to increase the efficacy of anticancer drugs whilst reducing off-target side effects. However, there remain uncertainties regarding the cellular uptake kinetics of nanoparticles which could have implications for nanop
Externí odkaz:
https://doaj.org/article/81b955807a9144d8933128dc95e0bd7e
Autor:
Joseph Leedale, Kieran J. Sharkey, Helen E. Colley, Áine M. Norton, David Peeney, Chantelle L. Mason, Jean G. Sathish, Craig Murdoch, Parveen Sharma, Steven D. Webb
Publikováno v:
iScience, Vol 4, Iss , Pp 84-96 (2018)
Summary: Many xenobiotics can bind to off-target receptors and cause toxicity via the dysregulation of downstream transcription factors. Identification of subsequent off-target toxicity in these chemicals has often required extensive chemical testing
Externí odkaz:
https://doaj.org/article/7a4f13c9f84141ecb44712980aa71c4a
Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease
Autor:
Jake G. Edmans, Bethany Ollington, Helen E. Colley, Martin E. Santocildes-Romero, Lars Siim Madsen, Paul V. Hatton, Sebastian G. Spain, Craig Murdoch
Publikováno v:
Journal of Controlled Release. 350:146-157
Chronic ulcerative oral mucosal inflammatory diseases, including oral lichen planus and recurrent aphthous stomatitis, are painful and highly prevalent, yet lack effective clinical management. In recent years, systemic biologic therapies, including m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee24c5fa03929f0cbd11680bbe2e90b9
https://doi.org/10.1016/j.jconrel.2022.08.016
https://doi.org/10.1016/j.jconrel.2022.08.016
Autor:
Lauren Tomlinson, Zhen Qi Lu, Robert A Bentley, Helen E. Colley, Craig Murdoch, Steven D. Webb, Michael J. Cross, Ian M. Copple, Parveen Sharma
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 112, Iss , Pp - (2019)
Dose-dependent cardiotoxicity is the leading adverse reaction seen in cancer patients treated with doxorubicin. Currently, dexrazoxane is the only approved drug that can partially protect against this toxicity in patients, however, its administration
Externí odkaz:
https://doaj.org/article/0819abf2d1dc48ffad04323516400d66
Autor:
Claire E. Lewis, Yvonne Reiss, Karl H. Plate, Craig Murdoch, Subhra K. Biswas, Carmen Urbich, Sunil Patel, Michele De Palma, Alexander Scholz, Andrea O. Tal, Seth B. Coffelt
TIE2-expressing monocytes/macrophages (TEM) are a highly proangiogenic subset of myeloid cells in tumors. Here, we show that circulating human TEMs are already preprogrammed in the circulation to be more angiogenic and express higher levels of such p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e85e2021e3d09bf23502327a5fd2d230
https://doi.org/10.1158/0008-5472.c.6500303
https://doi.org/10.1158/0008-5472.c.6500303
