Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Craig, Martens"'
Autor:
Julia R. Port, Jade C. Riopelle, Sarah van Tol, Arthur Wickenhagen, Eric Bohrnsen, Daniel E. Sturdevant, Rebecca Rosenke, Jamie Lovaglio, Justin Lack, Sarah L. Anzick, Kathleen Cordova, Kwe Claude Yinda, Patrick W. Hanley, Tony Schountz, Lon V. Kendall, Carl I. Shaia, Greg Saturday, Craig Martens, Benjamin Schwarz, Vincent J. Munster
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-15 (2024)
Abstract The ancestral sarbecovirus giving rise to SARS-CoV-2 is posited to have originated in bats. While SARS-CoV-2 causes asymptomatic to severe respiratory disease in humans, little is known about the biology, virus tropism, and immunity of SARS-
Externí odkaz:
https://doaj.org/article/04082be39d684a2987f4130c09c16462
Autor:
Natalia Malachowa, Daniel E. Sturdevant, Adeline R. Porter, Grant Martin, Craig Martens, Vinod Nair, Bryan Hansen, Stacy Ricklefs, Stephen G. Jenkins, Liang Chen, Barry N. Kreiswirth, Frank R. DeLeo
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Staphylococcus aureus is a leading cause of healthcare-associated infections globally. Vancomycin-resistant S. aureus (VRSA), those with high-level resistance [minimum inhibitory concentration (MIC) of 16–32 µg/mL vancomycin], are uncommo
Externí odkaz:
https://doaj.org/article/8cbaf093e0154a78bdd7d09c1332d7ee
Autor:
Roux-Cil Ferreira, Steven J. Reynolds, Adam A. Capoferri, Owen R. Baker, Erin E. Brown, Ethan Klock, Jernelle Miller, Jun Lai, Sharada Saraf, Charles Kirby, Briana Lynch, Jada Hackman, Sarah N. Gowanlock, Stephen Tomusange, Samiri Jamiru, Aggrey Anok, Taddeo Kityamuweesi, Paul Buule, Daniel Bruno, Craig Martens, Rebecca Rose, Susanna L. Lamers, Ronald M. Galiwango, Art F.Y. Poon, Thomas C. Quinn, Jessica L. Prodger, Andrew D. Redd
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105040- (2024)
Summary: Background: The principal barrier to an HIV cure is the presence of the latent viral reservoir (LVR), which has been understudied in African populations. From 2018 to 2019, Uganda instituted a nationwide rollout of ART consisting of Dolutegr
Externí odkaz:
https://doaj.org/article/7fa7f6eb718b411a877cdd47fd239934
Autor:
Julia R. Port, Claude Kwe Yinda, Jade C. Riopelle, Zachary A. Weishampel, Taylor A. Saturday, Victoria A. Avanzato, Jonathan E. Schulz, Myndi G. Holbrook, Kent Barbian, Rose Perry-Gottschalk, Elaine Haddock, Craig Martens, Carl. I. Shaia, Teresa Lambe, Sarah C. Gilbert, Neeltje van Doremalen, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Limited data is available on the effect of vaccination and previous virus exposure on the nature of SARS-CoV-2 transmission and immune-pressure on variants. To understand the impact of pre-existing immunity on SARS-CoV-2 airborne transmissio
Externí odkaz:
https://doaj.org/article/c78035e118024b6da19f983dc2509044
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Autor:
Julia R Port, Dylan H Morris, Jade C Riopelle, Claude Kwe Yinda, Victoria A Avanzato, Myndi G Holbrook, Trenton Bushmaker, Jonathan E Schulz, Taylor A Saturday, Kent Barbian, Colin A Russell, Rose Perry-Gottschalk, Carl Shaia, Craig Martens, James O Lloyd-Smith, Robert J Fischer, Vincent J Munster
Publikováno v:
eLife, Vol 12 (2024)
It remains poorly understood how SARS-CoV-2 infection influences the physiological host factors important for aerosol transmission. We assessed breathing pattern, exhaled droplets, and infectious virus after infection with Alpha and Delta variants of
Externí odkaz:
https://doaj.org/article/4c84307fc85040989316830046220c70
Autor:
Rahul Basu, Sundar Ganesan, Clayton W. Winkler, Sarah L. Anzick, Craig Martens, Karin E. Peterson, Iain D. C. Fraser
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract One of the key events in viral encephalitis is the ability of virus to enter the central nervous system (CNS). Several encephalitic viruses, including La Crosse Virus (LACV), primarily induce encephalitis in children, but not adults. This ph
Externí odkaz:
https://doaj.org/article/0f5c181a89be462b9b7e7fe061c0422c
Autor:
Jenny Wachter, Britney Cheff, Chad Hillman, Valentina Carracoi, David W. Dorward, Craig Martens, Kent Barbian, Glenn Nardone, L. Renee Olano, Margie Kinnersley, Patrick R. Secor, Patricia A. Rosa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The alternative sigma factor RpoS of Borrelia burgdorferi regulates a pathway implicated in tick transmission, mammalian infectivity and persistent infection. Here, the authors characterise the role of the RpoS negative regulator bbd18 and show that
Externí odkaz:
https://doaj.org/article/10bc3083e7a040999b17a6d6ed0ca572
Autor:
Olga A Maximova, Melodie L Weller, Tammy Krogmann, Daniel E Sturdevant, Stacy Ricklefs, Kimmo Virtaneva, Craig Martens, Kurt Wollenberg, Mahnaz Minai, Ian N Moore, Craig S Sauter, Juliet N Barker, W Ian Lipkin, Danielle Seilhean, Avindra Nath, Jeffrey I Cohen
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011544 (2023)
Astroviruses (AstVs) can cause of severe infection of the central nervous system (CNS) in immunocompromised individuals. Here, we identified a human AstV of the VA1 genotype, HAstV-NIH, as the cause of fatal encephalitis in an immunocompromised adult
Externí odkaz:
https://doaj.org/article/bb23eb1b94ac407f968c090e9fa6efa1
Autor:
Hong-Su Park, Yumiko Matsuoka, Cindy Luongo, Lijuan Yang, Celia Santos, Xueqiao Liu, Laura R. H. Ahlers, Ian N. Moore, Sharmin Afroz, Reed F. Johnson, Bernard A. P. Lafont, David W. Dorward, Elizabeth R. Fischer, Craig Martens, Siba K. Samal, Shirin Munir, Ursula J. Buchholz, Cyril Le Nouën
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Current vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are administered parenterally and appear to be more protective in the lower versus the upper respiratory tract. Vaccines are needed that directly stimulate
Externí odkaz:
https://doaj.org/article/b63359b706ef44b6802329d81a42cb7c