Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Autor: Iglesias, AI, Mishra, A, Vitart, V, Bykhovskaya, Y, Hoehn, R, Springelkamp, H, Cuellar-Partida, G, Gharahkhani, P, Bailey, JNC, Willoughby, CE, Li, X, Yazar, S, Nag, A, Khawaja, AP, Polasek, O, Siscovick, D, Mitchell, P, Tham, YC, Haines, JL, Kearns, LS, Hayward, C, Shi, Y, van Leeuwen, EM, Taylor, KD, Bonnemaijer, P, Rotter, JI, Martin, NG, Zeller, T, Mills, RA, Souzeau, E, Staffieri, SE, Jonas, JB, Schmidtmann, I, Boutin, T, Kang, JH, Lucas, SEM, Wong, TY, Beutel, ME, Wilson, JF, Uitterlinden, AG, Vithana, EN, Foster, PJ, Hysi, PG, Hewitt, AW, Khor, CC, Pasquale, LR, Montgomery, GW, Klaver, CCW, Aung, T, Pfeiffer, N, Mackey, DA, Hammond, CJ, Cheng, C-Y, Craig, JE, Rabinowitz, YS, Wiggs, JL, Burdon, KP, van Duijn, CM, MacGregor, S, Wang, JJ, Rochtchina, E, Attia, J, Scott, R, Holliday, EG, Baird, PN, Xie, J, Inouye, M, Viswanathan, A, Sim, X, Allingham, RR, Brilliant, MH, Budenz, DL, Christen, WG, Fingert, J, Friedman, DS, Gaasterland, D, Gaasterland, T, Hauser, MA, Kraft, P, Lee, RK, Lichter, PR, Liu, Y, Loomis, SJ, Moroi, SE, Pericak-Vance, MA, Realini, A, Richards, JE, Schuman, JS, Scott, WK, Singh, K, Sit, AJ, Vollrath, D, Weinreb, RN, Wollstein, G, Zack, DJ, Zhang, K, Donnelly, P, Barroso, I, Blackwell, JM, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Deloukas, P, Duncanson, A, Jankowski, J, Markus, HS, Mathew, CG, Palmer, CNA, Plomin, R, Rautanen, A, Sawcer, SJ, Trembath, RC, Wood, NW, Spencer, CCA, Band, G, Bellenguez, C, Freeman, C, Hellenthal, G, Giannoulatou, E, Pirinen, M, Pearson, R, Strange, A, Su, Z, Vukcevic, D, Langford, C, Hunt, SE, Edkins, S, Gwilliam, R, Blackburn, H, Bumpstead, SJ, Dronov, S, Gillman, M, Gray, E, Hammond, N, Jayakumar, A, McCann, OT, Liddle, J, Potter, SC, Ravindrarajah, R, Ricketts, M, Waller, M, Weston, P, Widaa, S, Whittaker, P, Grp, BMES-G, Consortium, N, Control, WTC

Publikováno v: Nature Communications
2019, ' Author Correction : Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases ', Nature Communications, vol. 10, no. 1, pp. 155 . https://doi.org/10.1038/s41467-018-07819-1
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-3 (2019)

Central corneal thickness (CCT) is a highly heritable trait associated with complex eye diseases such as keratoconus and glaucoma. We perform a genome-wide association meta-analysis of CCT and identify 19 novel regions. In addition to adding support

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http://ora.ox.ac.uk/objects/uuid:

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Autor: Duffy, David L, Zhu, Gu, Xin, Li, Sanna, Marianna, Iles, Mark M, Jacobs, Leonie C, Evans, David M, Yazar, Seyhan, Beesley, Jonathan, Law, Matthew H, Kraft, Peter, Visconti, Alessia, Taylor, John C, Lui, Fan, Wright, Margaret J, Henders, Anjali K, Bowdler, Lisa, Glass, Dan, Ikram, Arfan M, Uitterlinden, André G, Madden, Pamela A, Heath, Andrew C, Nelson, Elliot C, Green, Adele C, Chanock, Stephen, Barrett, Jennifer H, Brown, Matthew A, Hayward, Nicholas K, Macgregor, Stuart, Sturm, Richard A, Hewitt, Alex W, Kayser, Manfred, Hunter, David J, Newton Bishop, Julia A, Spector, Timothy D, Montgomery, Grant W, Mackey, David A, Smith, George Davey, Nijsten, Tamar E, Bishop, D Timothy, Bataille, Veronique, Falchi, Mario, Han, Jiali, Martin, Nicholas, G, Lee, Je, Brossard, M, Moses, Ek, Song, F, Kumar, R, Easton, Df, Pharoah, Pdp, Swerdlow, Aj, Kypreou, Kp, Harland, M, Randerson-Moor, J, Akslen, La, Andresen, Pa, Avril, Mf, Azizi, E, Scarrà, Gb, Brown, Km, Dębniak, T, Elder, De, Fang, S, Friedman, E, Galan, P, Ghiorzo, P, Gillanders, Em, Goldstein, Am, Gruis, Na, Hansson, J, Helsing, P, Hočevar, M, Höiom, V, Ingvar, C, Kanetsky, Pa, Chen, Wv, Landi, Mt, Lang, J, Lathrop, Gm, Lubiński, J, Mackie, Rm, Mann, Gj, Molven, A, Novaković, S, Olsson, H, Puig, S, Puig-Butille, Ja, Radford-Smith, Gl, van der Stoep, N, van Doorn, R, Whiteman, Dc, Craig, Je, Schadendorf, D, Simms, La, Burdon, Kp, Nyholt, Dr, Pooley, Ka, Orr, N, Stratigos, Aj, Cust, Ae, Ward, Sv, Schulze, Hj, Dunning, Am, Demenais, F, Amos, Ci.

Publikováno v: Nature Communications, 9:4774. Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Duffy, D L, Zhu, G, Li, X, Sanna, M, Iles, M M, Jacobs, L C, Evans, D M, Yazar, S, Beesley, J, Law, M H, Kraft, P, Visconti, A, Taylor, J C, Lui, F, Henders, A K, Bowdler, L, Glass, D, Ikram, A M, Uitterlinden, A G, Wright, M J, Madden, P A, Heath, A C, Nelson, E C, Green, A C, Chanock, S, Barrett, J H, Brown, M A, Hayward, N K, MacGregor, S, Sturm, R A, Hewitt, A W, Kayser, M, Hunter, D J, Newton Bishop, J A, Spector, T D, Montgomery, G W, Mackey, D A, Smith, G D, Nijsten, T E, Bishop, D T, Bataille, V, Falchi, M & Han, J & Martin, N G 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, no. 1, pp. 4774 . https://doi.org/10.1038/s41467-018-06649-5
Melanoma GWAS Consortium 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, no. 1, 4774 . https://doi.org/10.1038/s41467-018-06649-5
Duffy, D L, Zhu, G, Li, X, Sanna, M, Iles, M M, Jacobs, L C, Evans, D M, Yazar, S, Beesley, J, Law, M H, Kraft, P, Visconti, A, Taylor, J C, Lui, F, Wright, M J, Henders, A K, Bowdler, L, Glass, D, Ikram, A M, Uitterlinden, A G, Madden, P A, Heath, A C, Nelson, E C, Green, A C, Chanock, S, Barrett, J H, Brown, M A, Hayward, N K, MacGregor, S, Sturm, R A, Hewitt, A W, Lee, J E, Brossard, M, Moses, E K, Song, F, Kumar, R, Easton, D F, Pharoah, P D P, Swerdlow, A J, Kypreou, K P, Harland, M, Randerson-Moor, J, Akslen, L A, Andresen, P A, Avril, M F, Azizi, E, Scarrà, G B, Brown, K M & Dębniak, T & Smith, G D 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, 4774 . https://doi.org/10.1038/s41467-018-06649-5

The total number of acquired melanocytic nevi on the skin is strongly correlated with melanoma risk. Here we report a meta-analysis of 11 nevus GWAS from Australia, Netherlands, United Kingdom, and United States, comprising a total of 52,506 phenotyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdc17d2ba531806731975db2a684a16
https://www.repository.cam.ac.uk/handle/1810/288608

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

Autor: Tedja, MS, Wojciechowski, R, Hysi, PG, Eriksson, N, Furlotte, NA, Verhoeven, VJM, Iglesias, AI, Meester-Smoor, MA, Tompson, SW, Fan, Q, Khawaja, AP, Cheng, C-Y, Höhn, R, Yamashiro, K, Wenocur, A, Grazal, C, Haller, T, Metspalu, A, Wedenoja, J, Jonas, JB, Wang, YX, Xie, J, Mitchell, P, Foster, PJ, Klein, BEK, Klein, R, Paterson, AD, Hosseini, SM, Shah, RL, Williams, C, Teo, YY, Tham, YC, Gupta, P, Zhao, W, Shi, Y, Saw, W-Y, Tai, E-S, Sim, XL, Huffman, JE, Polašek, O, Hayward, C, Bencic, G, Rudan, I, Wilson, JF, Consortium, Cream, Team, 23Andme Research, Consortium, Uk Biobank Eye And Vision, Joshi, PK, Tsujikawa, A, Matsuda, F, Whisenhunt, KN, Zeller, T, Van Der Spek, PJ, Haak, R, Meijers-Heijboer, H, Van Leeuwen, EM, Iyengar, SK, Lass, JH, Hofman, A, Rivadeneira, F, Uitterlinden, AG, Vingerling, JR, Lehtimäki, T, Raitakari, OT, Biino, G, Concas, MP, Schwantes-An, T-H, Igo, RP, Cuellar-Partida, G, Martin, NG, Craig, JE, Gharahkhani, P, Williams, KM, Nag, A, Rahi, JS, Cumberland, PM, Delcourt, C, Bellenguez, C, Ried, JS, Bergen, AA, Meitinger, T, Gieger, C, Wong, TY, Hewitt, AW, Mackey, DA, Simpson, CL, Pfeiffer, N, Pärssinen, O, Baird, PN, Vitart, V, Amin, N, Van Duijn, CM, Bailey-Wilson, JE, Young, TL, Saw, S-M, Stambolian, D, Macgregor, S, Guggenheim, JA, Tung, JY, Hammond, CJ, Klaver, CCW

Publikováno v: Nature Genetics, 50(6), 834-848. Nature Publishing Group
CREAM Consortium 2018, ' Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error ', Nature Genetics, vol. 50, no. 6, pp. 834-848 . https://doi.org/10.1038/s41588-018-0127-7
the 23 and Me Research Team & Tedja, M S 2018, ' Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error ', Nature Genetics, vol. 50, no. 6, pp. 834-848 . https://doi.org/10.1038/s41588-018-0127-7
Nature Genetics, 50, 834-848
Nature genetics
Tedja, M S, Wojciechowski, R, Hysi, P, Eriksson, N, Furlotte, N A, Verhoeven, V J M, Iglesias, A I, Meester-Smoor, M A, Khawaja, A P, Cheng, C Y, Horn, R, Yamashiro, K, Wenocur, A, Grazal., C, Haller, T, Metspalu, A, Wedenoja, J, Jonas, J B, Wang, Y X, Mitchell, P, Hammond, C, Klaver, C C W, Consortium, T CREAM, Research Team & Eye and Vision Consortium, UK B 2018, ' Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error ', Nature Genetics, vol. 50, no. 6, pp. 834-848 . https://doi.org/10.1038/s41588-018-0127-7
Tedja, M S, Wojciechowski, R, Hysi, P G, Eriksson, N, Furlotte, N A, Verhoeven, V J M, Iglesias, A I, Meester-Smoor, M A, Tompson, S W, Fan, Q, Khawaja, A P, Cheng, C-Y, Höhn, R, Yamashiro, K, Wenocur, A, Grazal, C, Haller, T, Metspalu, A, Wedenoja, J, Jonas, J B, Wang, Y X, Xie, J, Mitchell, P, Foster, P J, Klein, B E K, Klein, R, Paterson, A D, Hosseini, S M, Shah, R L, Williams, C, Teo, Y Y, Tham, Y C, Gupta, P, Zhao, W, Shi, Y, Saw, W-Y, Tai, E-S, Sim, X L, Huffman, J E, Polašek, O, Hayward, C, Bencic, G, Rudan, I, Wilson, J F, Joshi, P K, Tsujikawa, A, Matsuda, F, Whisenhunt, K N & Zeller, T & Vitart, V 2018, ' Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error ', Nature Genetics, vol. 50, pp. 834-848 . https://doi.org/10.1038/s41588-018-0127-7
Nature Genetics, 50, 6, pp. 834-848
Nat. Genet. 50, 834-848 (2018)
Nature Genetics
CREAM, 23andMe Research Team, UK Biobank Eye and Vision Consortium, Aslam, T M & Bishop, P N 2018, ' Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error ', Nature Genetics, vol. 50, no. 6, pp. 834-848 . https://doi.org/10.1038/s41588-018-0127-7
Nature genetics, 50(6), 834-848. Nature Publishing Group

Skin affections after sulfur mustard (SM) exposure include erythema, blister formation and severe inflammation. An antidote or specific therapy does not exist. Anti-inflammatory compounds as well as substances counteracting SM-induced cell death are

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https://pure.knaw.nl/portal/en/publications/67984a46-b4c9-4c16-818c-32a0935f3046

Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

Autor: Law, M, Bishop, DT, Lee, JE, Brossard, M, Martin, NG, Moses, EK, Song, F, Barrett, JH, Kumar, R, Easton, DF, Pharoah, PDP, Swerdlow, AJ, Kypreou, KP, Taylor, JC, Harland, M, Randerson-Moor, J, Akslen, LA, Andresen, PA, Avril, MF, Azizi, E, Scarra, GB, Brown, KM, Debniak, T, Duffy, DL, Elder, DE, Fang, S, Friedman, E, Galan, P, Ghiorzo, P, Gillanders, EM, Goldstein, AM, Gruis, NE, Hansson, J, Helsing, P, Hocevar, M, Hoiom, V, Ingvar, C, Kanetsky, PA, Chen, WV, GenoMEL Consortium, Essen-Heidelberg Investigators, The SDH Study Group, Q-MEGA and QTWIN Investigators, AMFS Investigators, ATHENS Melanoma Study Group, Landi, MT, Lang, J, Lathrop, M, Lubinski, J, Mackie, RM, Mann, GJ, Molvern, A, Montgomery, GW, Novakovic, S, Olsson, H, Puig, S, Puig-Butille, JA, Qureshi, AA, Radford-Smith, GL, van der Stoep, N, van Doorn, R, Whiteman, DC, Craig, JE, Schadendorf, D, Simms, LA, Burdon, KP, Nyholt, DR, Pooley, KA, Orr, N, Stratigos, AJ, Cust, AE, Ward, SV, Hayward, NK, Han, J, Schulze, HJ, Dunning, AM, Newton-Bishop, JA, Demenais, F, Amos, CI, MacGregor, S, Iles, MM

Publikováno v: Nature genetics
Nature Genetics, 47(9), 987

© 2015 Nature America, Inc. All rights reserved.Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide associa

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https://hdl.handle.net/1887/107531

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia (vol 45, pg 314, 2013)

Autor: Verhoeven, Virginie, Hysi, PG, Wojciechowski, R, Fan, Q, Guggenheim, JA, Hohn, R, Macgregor, S, Hewitt, AW, Nag, A, Cheng, CY (Ching-Yu), Yonova-Doing, E, Zhou, X, Ikram, Kamran, Buitendijk, Gabriëlle, McMahon, G, Kemp, JP, St Pourcain, B, Simpson, CL, Makela, KM, Lehtimaki, T, Kahonen, M, Paterson, AD, Hosseini, SM, Wong, HS, Xu, L, Jonas, JB, Parssinen, O, Wedenoja, J, Yip, SP, Ho, DWH, Pang, CP, Chen, LJ, Burdon, KP, Craig, JE, Klein, BEK, Klein, R, Haller, T, Metspalu, A, Khor, CC, Tai, ES, Aung, T, Vithana, E, Tay, WT, Barathi, VA, Chen, Peng, Li, RY, Liao, JM, Zheng, YF, Ong, RT, Doring, A, Evans, DM, Timpson, NJ, Verkerk, AJMH, Meitinger, T, Raitakari, O, Hawthorne, F, Spector, TD, Karssen, Lennart, Pirastu, M, Murgia, F, Ang, W, Mishra, A, Montgomery, GW, Pennell, CE, Cumberland, PM, Cotlarciuc, I, Mitchell, P, Wang, JJ, Schache, M, Janmahasathian, S, Igo, RP, Lass, JH, Chew, E, KIyengar, S, Gorgels, TGMF (Theo), Rudan, I, Hayward, C, Wright, AF, Polasek, O, Vatavuk, Z, Wilson, JF, Fleck, B, Zeller, T, Mirshahi, A, Müller, Caspar, Uitterlinden, André, Rivadeneira, Fernando, Vingerling, Hans, Hofman, Bert, Oostra, Ben, Amin, Najaf, Bergen, Arthur, Teo, YY, Rahi, JS, Vitart, V, Williams, C, Baird, PN, Wong, TY (Tien Yin), Oexle, K, Pfeiffer, N, Mackey, DA, Young, TL, Duijn, Cornelia, Saw, SM, Bailey-Wilson, JE, Stambolian, D, Klaver, Caroline, Hammond, CJ

Publikováno v: Nature Genetics, 45(6), 712-712. Nature Publishing Group

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https://pure.eur.nl/en/publications/929fed19-1960-493d-9153-0fd39eddeabb