Výsledky vyhledávání - "Craig, Garen"

Akademický článek

Partially native intermediates mediate misfolding of SOD1 in single-molecule folding trajectories

Autor: Supratik Sen Mojumdar, Zackary N. Scholl, Derek R. Dee, Logan Rouleau, Uttam Anand, Craig Garen, Michael T. Woodside

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

Misfolding of superoxide dismutase 1 (SOD1) is linked to amyotrophic lateral sclerosis. Here the authors characterize the unfolding/refolding of single SOD1 molecules using optical tweezers, identifying partially folded intermediates that lead to mis

Externí odkaz: https://doaj.org/article/f1f068ff3345441b973c4a6b29d464b1

Zobrazit plný text záznamu

Direct observation of prion-like propagation of misfolding in single protein molecules

Autor: Krishna P. Neupane, Abhishek Narayan, Supratik Sen Mojumdar, Gaurav Adhikari, Craig Garen, Michael T. Woodside

Publikováno v: Biophysical Journal. 121:417a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::734a358570d3380e7b31b28bcee2bb8d
https://doi.org/10.1016/j.bpj.2021.11.675

Zobrazit plný text záznamu

The Crystal Structure of 1-D-myo-Inosityl 2-Acetamido-2-deoxy-α-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold

Autor: Jason T. Maynes, Maia M. Cherney, Dorit Arad, Yossef Av-Gay, Michael N.G. James, Robert C. Fahey, Gerald L. Newton, Craig Garen

Publikováno v: Journal of Biological Chemistry. 278:47166-47170

Mycothiol (1-D-myo-inosityl 2-(N-acetyl-L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside, MSH or AcCys-GlcN-inositol (Ins)) is the major reducing agent in actinomycetes, including Mycobacterium tuberculosis. The biosynthesis of MSH involves a deacet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce5165cf8ed780bfff65b99626e7506
https://doi.org/10.1074/jbc.m308914200

Zobrazit plný text záznamu

Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole

Autor: Isabelle H, Barrette-Ng, Kenneth K-S, Ng, Brian L, Mark, Danny, Van Aken, Maia M, Cherney, Craig, Garen, Yuliya, Kolodenko, Alexander E, Gorbalenya, Eric J, Snijder, Michael N G, James

Publikováno v: The Journal of biological chemistry. 277(42)

Arteriviruses are enveloped, positive-stranded RNA viruses and include pathogens of major economic concern to the swine- and horse-breeding industries. The arterivirus replicase gene encodes two large precursor polyproteins that are processed by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e14ccca821023dd4bab217c37d97d59
https://pubmed.ncbi.nlm.nih.gov/12163505

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání