Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Craig, April"'
Autor:
Jacobus Pfisterer, Sean C. Dowdy, Ellen L. Goode, Lynn C. Hartmann, Timothy Perren, Richard Kaplan, Mahesh Parmar, Andrew C. Embleton, Jeremy Chien, Ulrich Canzler, Alexander Burges, Willibald Schroeder, Klaus Baumann, Sven Mahner, Felix Hilpert, Andreas du Bois, Friedrich Kommoss, Viji Shridhar, Craig April, Matthew J. Maurer, Jian-Bing Fan, Shaun M. Riska, Chen Wang, Gottfried E. Konecny, Ann L. Oberg, Boris Winterhoff, Stefan Kommoss
Purpose: Recent progress in understanding the molecular biology of epithelial ovarian cancer has not yet translated into individualized treatment for these women or improvements in their disease outcome. Gene expression has been utilized to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b2502926a74417f07479181ec8871f
https://doi.org/10.1158/1078-0432.c.6526419.v1
https://doi.org/10.1158/1078-0432.c.6526419.v1
Autor:
Jacobus Pfisterer, Sean C. Dowdy, Ellen L. Goode, Lynn C. Hartmann, Timothy Perren, Richard Kaplan, Mahesh Parmar, Andrew C. Embleton, Jeremy Chien, Ulrich Canzler, Alexander Burges, Willibald Schroeder, Klaus Baumann, Sven Mahner, Felix Hilpert, Andreas du Bois, Friedrich Kommoss, Viji Shridhar, Craig April, Matthew J. Maurer, Jian-Bing Fan, Shaun M. Riska, Chen Wang, Gottfried E. Konecny, Ann L. Oberg, Boris Winterhoff, Stefan Kommoss
Appendix 1: Additional Methods for Subtype Assignment Figure S1. Consistency check between published supervised classification vs. novel unsupervised clustering in TCGA Figure S2. Subclasses were computed by applying a consensus NMF clustering method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f47e43b985baa83ab3b2979f7e66da9
https://doi.org/10.1158/1078-0432.22466772.v1
https://doi.org/10.1158/1078-0432.22466772.v1
Autor:
Reuben S. Harris, Scott H. Kaufmann, Hugues Sicotte, Ellen L. Goode, Kimberly R. Kalli, Lynn C. Hartmann, Elizabeth M. Swisher, Jeremy Chien, John Peden, Zoya Kingsbury, Sean Humphray, Russell Grocock, Jian-Bing Fan, R. Keira Cheetham, Marina Bibikova, David Bentley, Craig April, Debra A. Bell, Viji Shridhar, Julie M. Cunningham, Ann L. Oberg, Matthew J. Maurer, Yuji Zhang, Ying Li, William L. Brown, Emily K. Law, Jason B. Nikas, Rachel I. Vogel, Anurag Rathore, Nuri A. Temiz, Michael A. Carpenter, Michael B. Burns, Steven N. Hart, Brandon Leonard
PDF file - 481K, Table S1: Cell line information Table S2: Quantitative PCR primer and probe sequences. Table S3: Non-malignant tissues tested Table S4: Early stage serous ovarian tumors used in sequence analyses Table S5: Additional ovarian tumor sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257df24e001a06c97dcee7ba0d83e354
https://doi.org/10.1158/0008-5472.22396406.v1
https://doi.org/10.1158/0008-5472.22396406.v1
Autor:
Sreejith J. Nair, Xiaowen Zhang, Huai-Chin Chiang, Md Jamiul Jahid, Yao Wang, Paula Garza, Craig April, Neeraj Salathia, Tapahsama Banerjee, Fahad S. Alenazi, Jianhua Ruan, Jian-Bing Fan, Jeffrey D. Parvin, Victor X. Jin, Yanfen Hu, Rong Li
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
COBRA1 is a BRCA1-binding protein and, as part of the negative elongation factor, regulates RNA polymerase II pausing and transcription elongation. Here, the authors show that tissue-specific deletion of mouse Cobra1 inhibits postnatal mammary gland
Externí odkaz:
https://doaj.org/article/e8b1af6dbaf6435f9056729025693328
Autor:
Haihui Pan, Kunhua Qin, Zhanyong Guo, Yonggang Ma, Craig April, Xiaoli Gao, Thomas G. Andrews, Alex Bokov, Jianhua Zhang, Yidong Chen, Susan T. Weintraub, Jian-Bing Fan, Degeng Wang, Yanfen Hu, Gregory J. Aune, Merry L. Lindsey, Rong Li
Publikováno v:
Cell Reports, Vol 7, Iss 1, Pp 79-85 (2014)
Negative elongation factor (NELF) is known to enforce promoter-proximal pausing of RNA polymerase II (Pol II), a pervasive phenomenon observed across multicellular genomes. However, the physiological impact of NELF on tissue homeostasis remains uncle
Externí odkaz:
https://doaj.org/article/68c97ea5df3a40368658fb58edf0679e
Autor:
Kevin Huang, Yin Shen, Zhigang Xue, Marina Bibikova, Craig April, Zhenshan Liu, Linzhao Cheng, Andras Nagy, Matteo Pellegrini, Jian-Bing Fan, Guoping Fan
Publikováno v:
Stem Cell Reports, Vol 2, Iss 1, Pp 36-43 (2014)
Whether human induced pluripotent stem cells (hiPSCs) are epigenetically identical to human embryonic stem cells (hESCs) has been debated in the stem cell field. In this study, we analyzed DNA methylation patterns in a large number of hiPSCs (n = 114
Externí odkaz:
https://doaj.org/article/3f994e6bafe54f479bdb190c04a0a984
Autor:
Haihui Pan, Xiayan Zhao, Xiaowen Zhang, Mohamed Abouelsoud, Jianlong Sun, Craig April, Asma Amleh, Jian-Bing Fan, Yanfen Hu, Rong Li
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127422 (2015)
Negative elongation factor (NELF), a four-subunit protein complex in metazoan, plays an important role in regulating promoter-proximal pausing of RNA polymerase II (RNAPII). Genetic studies demonstrate that the B subunit of mouse NELF (NELF-B) is cri
Externí odkaz:
https://doaj.org/article/37bf9d3504214efb8b60d47f553888e1
Autor:
Kensuke Kojima, Craig April, Claudia Canasto-Chibuque, Xintong Chen, Manjeet Deshmukh, Anu Venkatesh, Poh Seng Tan, Masahiro Kobayashi, Hiromitsu Kumada, Jian-Bing Fan, Yujin Hoshida
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86961 (2014)
Archived tissues from previously completed prospective trials represent invaluable resource for biomarker development. However, such specimens are often stored as sections on glass slides, in which RNA is severely degraded due to prolonged air exposu
Externí odkaz:
https://doaj.org/article/e481a6c576674659b5e62f94bc7c05e9
Autor:
Maggie L Chow, Tiziano Pramparo, Mary E Winn, Cynthia Carter Barnes, Hai-Ri Li, Lauren Weiss, Jian-Bing Fan, Sarah Murray, Craig April, Haim Belinson, Xiang-Dong Fu, Anthony Wynshaw-Boris, Nicholas J Schork, Eric Courchesne
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002592 (2012)
Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation in the autism literature; but association, linkage, and expression
Externí odkaz:
https://doaj.org/article/271731ca984f4c7eb0af7943a32f5218
Autor:
Stefan Bentink, Benjamin Haibe-Kains, Thomas Risch, Jian-Bing Fan, Michelle S Hirsch, Kristina Holton, Renee Rubio, Craig April, Jing Chen, Eliza Wickham-Garcia, Joyce Liu, Aedin Culhane, Ronny Drapkin, John Quackenbush, Ursula A Matulonis
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30269 (2012)
Ovarian cancer is the fifth leading cause of cancer death for women in the U.S. and the seventh most fatal worldwide. Although ovarian cancer is notable for its initial sensitivity to platinum-based therapies, the vast majority of patients eventually
Externí odkaz:
https://doaj.org/article/882777890708423181fff7a4cf12a1ab