Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Craggs PD"'
Autor:
Spaull, Gang Yao, Mohammed Ghiboub, van Limbergen J, Blunt Ce, Danny A. Zwijnenburg, Mitchell Dj, Umesh Kumar, Gatfield K, O’Keefe Hp, Harrison La, Patel A, Jan Koster, Peter Henneman, Craggs Pd, Coffin A, Bruton G, Shillings A, Lunven L, Hutchinson S, de Winther Mp, de Jonge Wj, Hamer N, Ishtu Hageman, Theodorus B. M. Hakvoort, Watson Rj, Rabinder Kumar Prinjha, David F. Tough, Bingham Rp, Sloan La, Olaf Welting, Li Yim Ay, Nicola Harker
Speckled 140 KDa (SP140) is a nuclear body protein, mainly expressed in immune cells, which contains multiple domains suggestive of an epigenetic reader function; namely a bromodomain, a PHD domain and a SAND domain. Single nucleotide polymorphisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0853e3654cd91a0fa9e3e2892f2ee4a5
https://doi.org/10.1101/2020.08.10.239475
https://doi.org/10.1101/2020.08.10.239475
Autor:
Hirst DJ; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Bamborough P; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Al-Mahdi N; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Angell DC; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Barnett HA; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Baxter A; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Bit RA; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Brown JA; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Chung CW; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Craggs PD; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Davis RP; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Demont EH; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Ferrie A; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Gordon LJ; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Harada I; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Ho TCT; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Holyer ID; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Hooper-Greenhill E; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Jones KL; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Lindon MJ; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Lovatt C; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Lugo D; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Maller C; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., McGonagle G; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Messenger C; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Mitchell DJ; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Pascoe DD; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Patel VK; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Patten C; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Poole DL; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Shah RR; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Rioja I; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Stafford KAJ; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Tape D; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Taylor S; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Theodoulou NH; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Tomlinson L; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Wall ID; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Wellaway CR; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., White G; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Prinjha RK; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Humphreys PG; GSK Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Jun 27; Vol. 67 (12), pp. 10464-10489. Date of Electronic Publication: 2024 Jun 12.
Autor:
Lay CS, Thomas DA, Evans JP, Campbell M, McCombe K, Phillipou AN, Gordon LJ, Jones EJ, Riching K, Mahmood M, Messenger C, Carver CE, Gatfield KM, Craggs PD
Publikováno v:
Cell chemical biology [Cell Chem Biol] 2023 Dec 21; Vol. 30 (12), pp. 1692.
Autor:
Bradley E; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K.; Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, U.K., Fusani L; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K.; Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, U.K., Chung CW; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Craggs PD; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Demont EH; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Humphreys PG; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Mitchell DJ; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Phillipou A; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Rioja I; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Shah RR; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Wellaway CR; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Prinjha RK; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Palmer DS; Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, U.K., Kerr WJ; Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, U.K., Reid M; Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, U.K., Wall ID; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K., Cookson R; GSK, Medicines Research Centre, Stevenage SG1 2NY, Hertfordshire, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Dec 14; Vol. 66 (23), pp. 15728-15749. Date of Electronic Publication: 2023 Nov 15.
Autor:
Thomas MG; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., McGonagle K; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Rowland P; GlaxoSmithKline, Chemistry, Medicines Research Centre, Gunnels Wood Road, Stevenage, U.K., SG1 2NY., Robinson DA; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Dodd PG; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Camino-Díaz I; GlaxoSmithKline, Discovery DMPK, IVIVT, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., Campbell L; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Cantizani J; GlaxoSmithKline, Global Health R&D, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., Castañeda P; GlaxoSmithKline, Discovery DMPK, IVIVT, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., Conn D; GlaxoSmithKline, Chemistry, Medicines Research Centre, Gunnels Wood Road, Stevenage, U.K., SG1 2NY., Craggs PD; GlaxoSmithKline, Chemistry, Medicines Research Centre, Gunnels Wood Road, Stevenage, U.K., SG1 2NY., Edwards D; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Ferguson L; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Fosberry A; GlaxoSmithKline, Chemistry, Medicines Research Centre, Gunnels Wood Road, Stevenage, U.K., SG1 2NY., Frame L; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Goswami P; GlaxoSmithKline, Chemistry, Medicines Research Centre, Gunnels Wood Road, Stevenage, U.K., SG1 2NY., Hu X; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Korczynska J; GlaxoSmithKline, Chemistry, Medicines Research Centre, Gunnels Wood Road, Stevenage, U.K., SG1 2NY., MacLean L; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Martin J; GlaxoSmithKline, Global Health R&D, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., Mutter N; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Osuna-Cabello M; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Paterson C; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Peña I; GlaxoSmithKline, Global Health R&D, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., Pinto EG; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Pont C; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Riley J; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Shishikura Y; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Simeons FRC; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Stojanovski L; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Thomas J; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Wrobel K; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Young RJ; Blue Burgundy Ltd, Ampthill, Bedfordshire, U.K., MK45 2AD., Zmuda F; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Zuccotto F; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Read KD; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Gilbert IH; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH., Marco M; GlaxoSmithKline, Global Health R&D, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., Miles TJ; GlaxoSmithKline, Global Health R&D, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., Manzano P; GlaxoSmithKline, Global Health R&D, Severo Ochoa 2, PTM, Tres Cantos, Madrid ES 28760, Spain., De Rycker M; Drug Discovery Unit, University of Dundee, School of Life Sciences, Dow Street, Dundee, U.K., DD1 5EH.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Aug 10; Vol. 66 (15), pp. 10413-10431. Date of Electronic Publication: 2023 Jul 28.
Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells.
Autor:
Lay CS; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Kilpatrick LE; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.; Division of Bimolecular Science and Medicinal Chemistry, School of Pharmacy, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Craggs PD; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK.; Crick-GSK Biomedical Linklabs, GlaxoSmithKline, Stevenage, UK., Hill SJ; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.
Publikováno v:
British journal of pharmacology [Br J Pharmacol] 2023 Jun; Vol. 180 (11), pp. 1444-1459. Date of Electronic Publication: 2023 Jan 10.
Autor:
Lay CS; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.; Chemical Biology, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK., Isidro-Llobet A; Chemical Biology, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK., Kilpatrick LE; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.; Division of Bimolecular Science and Medicinal Chemistry, School of Pharmacy, Biodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK., Craggs PD; Chemical Biology, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK. peter.d.craggs@gsk.com.; Crick-GSK Biomedical Linklabs, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK. peter.d.craggs@gsk.com., Hill SJ; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, NG7 2UH, UK. stephen.hill@nottingham.ac.uk.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK. stephen.hill@nottingham.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 May 19; Vol. 14 (1), pp. 2882. Date of Electronic Publication: 2023 May 19.
Autor:
Humphreys PG; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Anderson NA; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Bamborough P; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Baxter A; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Chung CW; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Cookson R; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Craggs PD; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Dalton T; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Fournier JCL; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Gordon LJ; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Gray HF; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Gray MW; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Gregory R; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Hirst DJ; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Jamieson C; WestCHEM, Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, U.K., Jones KL; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Kessedjian H; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Lugo D; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., McGonagle G; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Patel VK; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Patten C; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Poole DL; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Prinjha RK; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Ramirez-Molina C; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Rioja I; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Seal G; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Stafford KAJ; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Shah RR; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Tape D; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Theodoulou NH; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Tomlinson L; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Ukuser S; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Wall ID; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., Wellaway N; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K., White G; GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Nov 24; Vol. 65 (22), pp. 15174-15207. Date of Electronic Publication: 2022 Nov 15.
Autor:
Craggs PD; Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute, London NW1 1AT, United Kingdom; GSK-Francis Crick Institute Linklabs, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, United Kingdom., de Carvalho LPS; Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute, London NW1 1AT, United Kingdom. Electronic address: Luiz.Carvalho@crick.ac.uk.
Publikováno v:
Current opinion in microbiology [Curr Opin Microbiol] 2022 Oct; Vol. 69, pp. 102191. Date of Electronic Publication: 2022 Aug 12.
Autor:
Ghiboub M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Immuno-Epigenetics, Adaptive Immunity Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.; Department of Pediatrics, Division of Pediatric Gastroenterology & Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Koster J; Department of Oncogenomics, Amsterdam University Medical Centers, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, the Netherlands., Craggs PD; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Li Yim AYF; Immuno-Epigenetics, Adaptive Immunity Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.; Department of Clinical Genetics, Genome Diagnostics Laboratory, Amsterdam Reproduction & Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Shillings A; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Hutchinson S; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Bingham RP; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Gatfield K; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Hageman IL; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Yao G; GlaxoSmithKline, Cambridge, MA, USA., O'Keefe HP; GlaxoSmithKline, Cambridge, MA, USA., Coffin A; Constellation Pharmaceuticals, Cambridge, MA, USA., Patel A; WuXi AppTec, Cambridge, MA, USA., Sloan LA; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Mitchell DJ; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Hayhow TG; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Lunven L; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Watson RJ; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Blunt CE; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Harrison LA; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Bruton G; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Kumar U; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., Hamer N; Immuno-Epigenetics, Adaptive Immunity Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., Spaull JR; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK., Zwijnenburg DA; Department of Oncogenomics, Amsterdam University Medical Centers, University of Amsterdam and Cancer Center Amsterdam, Amsterdam, the Netherlands., Welting O; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Hakvoort TBM; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Te Velde AA; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., van Limbergen J; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Department of Pediatrics, Division of Pediatric Gastroenterology & Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Henneman P; Department of Clinical Genetics, Genome Diagnostics Laboratory, Amsterdam Reproduction & Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Prinjha RK; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., de Winther MPJ; Department of Medical Biochemistry, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Institute for Cardiovascular Prevention (IPEK), Munich, Germany., Harker NR; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK., Tough DF; Immunology Research Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK. david.f.tough@gsk.com., de Jonge WJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. w.j.dejonge@amsterdamumc.nl.; Department of Surgery, University of Bonn, Bonn, Germany. w.j.dejonge@amsterdamumc.nl.
Publikováno v:
BMC biology [BMC Biol] 2022 Aug 19; Vol. 20 (1), pp. 182. Date of Electronic Publication: 2022 Aug 19.