Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Crabtree, MJ"'
Autor:
Chu, SM, Heather, LC, Chuaiphichai, S, Nicol, T, Wright, B, Miossec, M, Bendall, JK, Douglas, G, Crabtree, MJ, Channon, KM
Publikováno v:
Experimental Physiology.
New Findings What is the central question of this study? What are the physiological roles of cardiomyocyte-derived tetrahydrobiopterin (BH4) in cardiac metabolism and stress response? What is the main finding and its importance? Cardiomyocyte BH4 has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f256ef3dbe775b97f3f6293441bf8698
https://doi.org/10.1113/ep090795
https://doi.org/10.1113/ep090795
Autor:
Cronin, SJF, Yu, W, Hale, A, Licht-Mayer, S, Crabtree, MJ, Korecka, JA, Tretiakov, EO, Sealey-Cardona, M, Somlyay, M, Onji, M, An, M, Fox, JD, Turnes, BL, Gomez-Diaz, C, da Luz Scheffer, D, Cikes, D, Nagy, V, Weidinger, A, Wolf, A, Reither, H, Chabloz, A, Kavirayani, A, Rao, S, Andrews, N, Latremoliere, A, Costigan, M, Douglas, G, Freitas, FC, Pifl, C, Walz, R, Konrat, R, Mahad, DJ, Koslov, AV, Latini, A, Isacson, O, Harkany, T, Hallett, PJ, Bagby, S, Woolf, CJ, Channon, KM, Je, HS, Penninger, JM
Dopa-responsive dystonia (DRD) and Parkinson’s disease (PD) are movement disorders caused by the dysfunction of nigrostriatal dopaminergic neurons. Identifying druggable pathways and biomarkers for guiding therapies is crucial due to the debilitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cbcda9c9401e3344d593e6596e8ff5
https://doi.org/10.1101/2023.05.08.539795
https://doi.org/10.1101/2023.05.08.539795
Autor:
Diotallevi, M, Nicol, T, Ayaz, F, Bailey, J, Shaw, A, McNeill, E, Davies, B, Channon, KM, Crabtree, MJ
Publikováno v:
Journal of visualized experiments : JoVE. (183)
Macrophages are derived from hematopoietic progenitor cells throughout the body, are central to inflammatory processes, and participate in innate and adaptive immune responses. In vitro study of macrophages can be undertaken by ex vivo culture from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e40d99b929b3dc5a17cacccf4a65d962
https://pubmed.ncbi.nlm.nih.gov/35723458
https://pubmed.ncbi.nlm.nih.gov/35723458
Autor:
Douglas, G, Hale, AB, Patel, J, Chuaiphichai, S, Al Haj Zen, A, Rashbrook, VS, Trelfa, L, Crabtree, MJ, McNeill, E, Channon, KM
Publikováno v:
Cardiovascular Research
Aims GTP cyclohydrolase I catalyses the first and rate-limiting reaction in the synthesis of tetrahydrobiopterin (BH4), an essential cofactor for nitric oxide synthases (NOS). Both eNOS and iNOS have been implicated in the progression of atherosclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffa679c0bf6f36127e8cd0345a8bf08c
http://europepmc.org/articles/PMC6054219
http://europepmc.org/articles/PMC6054219
Autor:
Upmacis, RK, Crabtree, MJ, Deeb, RS, Shen, H, Lane, PB, Benguigui, LES, Maeda, N, Hajjar, DP, Gross, SS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8b5c94cdb17f0e6d8b58638eb987bdc1
https://ora.ox.ac.uk/objects/uuid:c613a54f-75cf-4ec3-9f50-0852ce8ede7b
https://ora.ox.ac.uk/objects/uuid:c613a54f-75cf-4ec3-9f50-0852ce8ede7b
Autor:
Kalla, M, Chotalia, M, Coughlan, C, Hao, G, Crabtree, MJ, Tomek, J, Bub, G, Paterson, DJ, Herring, N
Implantable cardiac vagal nerve stimulators are a promising treatment for ventricular arrhythmia in patients with heart failure. Animal studies suggest the antifibrillatory effect may be nitric oxide (NO) dependent, although the exact site of action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0b4ce280f0143549191c14ac6d25a0f8
https://ora.ox.ac.uk/objects/uuid:69427ef7-2cdc-47c7-8499-3ae642ee8702
https://ora.ox.ac.uk/objects/uuid:69427ef7-2cdc-47c7-8499-3ae642ee8702