Zobrazeno 1 - 10
of 1 247
pro vyhledávání: '"CpG Island Methylator Phenotype"'
Autor:
Pyoung Hwa Park, Kelsey Keith, Gennaro Calendo, Jaroslav Jelinek, Jozef Madzo, Raad Z. Gharaibeh, Jayashri Ghosh, Carmen Sapienza, Christian Jobin, Jean-Pierre J. Issa
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The intestinal microbiota is an important environmental factor implicated in CRC development. Intriguingly, modulation of DNA methylation by gut microbiota has been reported in preclinical models, although the relationship between tumor-infiltrating
Externí odkaz:
https://doaj.org/article/2856375f622b4bc5bda4e07109ea89fe
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101461- (2024)
Colorectal cancer (CRC) is a complicated illness caused by a mix of hereditary and environmental factors. It is one of the most common malignancies worldwide, yet it is also one of the most curable if detected early. There are three types of molecula
Externí odkaz:
https://doaj.org/article/a594d66f3b9a476d986c1012cada4b9c
Autor:
Yun-Yun Weng, Ming-Yii Huang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5243 (2024)
Synchronous colorectal cancer (sCRC) is characterized by the occurrence of more than one tumor within six months of detecting the first tumor. Evidence suggests that sCRC might be more common in the serrated neoplasia pathway, marked by the CpG islan
Externí odkaz:
https://doaj.org/article/cd039b23311d4b13a58792135b2248d7
Autor:
Pengfei Gu, Yu Zeng, Weike Ma, Wei Zhang, Yu Liu, Fengli Guo, Xianhui Ruan, Jiadong Chi, Xiangqian Zheng, Ming Gao
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
CpG island methylator phenotype (CIMP), characterized by the concurrent and widespread hypermethylation of a cluster of CpGs, has been reported to play an important role in carcinogenesis. Limited studies have explored the role of CIMP in papillary t
Externí odkaz:
https://doaj.org/article/bc4651b5a7144559b0474ccaa436b965
Autor:
Yoshiki Okita, Minoru Koi, Koki Takeda, Ryan Ross, Bhramar Mukherjee, Erika Koeppe, Elena M. Stoffel, Joseph A. Galanko, Amber N. McCoy, Temitope O. Keku, Yoshinaga Okugawa, Takahito Kitajima, Yuji Toiyama, Eric Martens, John M. Carethers
Publikováno v:
Gut Pathogens, Vol 12, Iss 1, Pp 1-5 (2020)
Abstract Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylation phenotype (CIMP). Fn infect
Externí odkaz:
https://doaj.org/article/99ec52fbc04644c492b5dea7f470933d
Autor:
Yu Z, Yu H, Zou Q, Huang Z, Wang X, Tang G, Bai L, Zhou C, Zhuang Z, Xie Y, Wang H, Xu G, Chen Z, Fu X, Huang M, Luo Y
Publikováno v:
OncoTargets and Therapy, Vol Volume 13, Pp 309-321 (2020)
Zhuojun Yu, 1–3,* Huichuan Yu, 1,* Qi Zou, 1, 4 Zenghong Huang, 1, 2 Xiaolin Wang, 1 Guannan Tang, 1 Liangliang Bai, 1 Chuanhai Zhou, 1–3 Zhuokai Zhuang, 1, 2 Yumo Xie, 1, 2 Heng Wang, 1 Gaopo Xu, 1 Zijian Chen, 1, 5 Xinhui Fu, 1, 6 Meijin Huang,
Externí odkaz:
https://doaj.org/article/45c8e69ae14349e4b10a10d9dfdf375f
Autor:
Melanie Ehrlich
Publikováno v:
Epigenetics, Vol 14, Iss 12, Pp 1141-1163 (2019)
Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-malignant diseases. This is consistent with numerous findings about differentiation-associated changes in DNA methylation at promoters, enhancers, gene bodies, an
Externí odkaz:
https://doaj.org/article/d0b627c27eaa4058bb53299a04817d6b
Autor:
Jiang Liu, Li Tang, Jinhua Yi, Guimei Li, Youwang Lu, Yu Xu, Shuhua Zhao, Rui Mao, Xiaolu Li, Li Ren, Kunhua Wang
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Molecular characteristics of CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) have been well documented in Western, but not in Chinese, populations. Methods We investigated the incidence of CIMP, BRAF/KRAS mutatio
Externí odkaz:
https://doaj.org/article/055e12da3bbd4793874516aef07295a6
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