Zobrazeno 1 - 1
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pro vyhledávání: '"Cp, cryptophycin"'
Publikováno v:
The Journal of Biological Chemistry
Cryptophycin-52 (Cp-52) is potentially the most potent anticancer drug known, with IC50 values in the low picomolar range, but its binding site on tubulin and mechanism of action are unknown. Here, we have determined the binding site of Cp-52, and it