The shifting landscape of genetic alterations separating endometriosis and ovarian endometrioid carcinoma

Autor: Gaia-Oltean, Adriana I, Pop, Laura A, Cojocneanu, Roxana M, Buse, Mihail, Zimta, Andreea A, Kubelac, Paul, Irimie, Alexandru, Coza, Ovidiu F, Roman, Horace, Berindan-Neagoe, Ioana

Publikováno v: Am J Cancer Res

Ovarian cancer is one of the most common cancers worldwide, and is associated with a prior diagnosis of endometriosis in several cases. Our aim was to correlate genetic and methylation profile of ovarian endometrioid ovarian cancer and endometriosis

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https://europepmc.org/articles/PMC8085850/

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The shifting landscape of genetic alterations separating endometriosis and ovarian endometrioid carcinoma.

Autor: Gaia-Oltean AI; Department of Surgical Oncology and Gynecological Oncology, University of Medicine and Pharmacy Iuliu Hatieganu Cluj-Napoca 400012, Romania., Pop LA; Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Cluj 400337, Romania., Cojocneanu RM; Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Cluj 400337, Romania., Buse M; MEDFUTURE Research Center for Advanced Medicine, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca 400000, Romania., Zimta AA; MEDFUTURE Research Center for Advanced Medicine, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca 400000, Romania., Kubelac P; Department of Medical Oncology, The Oncology Institute 'Ion Chiricuta' Cluj-Napoca, Romania.; 'Iuliu Hatieganu' University of Medicine and Pharmacy Cluj-Napoca 400015, Romania., Irimie A; Department of Surgical Oncology and Gynecological Oncology, University of Medicine and Pharmacy Iuliu Hatieganu Cluj-Napoca 400012, Romania.; Department of Surgery, The Oncology Institute 'Prof. Dr. Ion Chiricuta' Cluj-Napoca 400012, Romania., Coza OF; Department of Radiotherapy II, The Oncology Institute 'Prof. Dr. I Chiricuta' Cluj-Napoca, Cluj 400015, Romania., Roman H; Center of Endometriosis, Clinique Tivoli-Ducos Bordeaux, France., Berindan-Neagoe I; Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Cluj 400337, Romania.; Department of Functional Genomics and Experimental Pathology, The Oncology Institute 'Prof. Dr. I Chiricuta' Cluj-Napoca, Cluj 400015, Romania.

Publikováno v: American journal of cancer research [Am J Cancer Res] 2021 Apr 15; Vol. 11 (4), pp. 1754-1769. Date of Electronic Publication: 2021 Apr 15 (Print Publication: 2021).