Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Coyne, Alyssa"'
Autor:
Liu, Guangbo, Coyne, Alyssa N., Pei, Fen, Vaughan, Spencer, Chaung, Matthew, Zarnescu, Daniela C., Buchan, J. Ross
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron degenerative disease. ALS-affected motor neurons exhibit aberrant localization of a nuclear RNA binding protein, TDP-43, into cytoplasmic aggregates, which contributes to pathology via uncle
Externí odkaz:
http://hdl.handle.net/10150/626460
http://arizona.openrepository.com/arizona/handle/10150/626460
http://arizona.openrepository.com/arizona/handle/10150/626460
Autor:
Coyne, Alyssa N., Lorenzini, Ileana, Chou, Ching-Chieh, Torvund, Meaghan, Rogers, Robert S., Starr, Alexander, Zaepfel, Benjamin L., Levy, Jennifer, Johannesmeyer, Jeffrey, Schwartz, Jacob C., Nishimune, Hiroshi, Zinsmaier, Konrad, Rossoll, Wilfried, Sattler, Rita, Zarnescu, Daniela C.
Amyotrophic lateral sclerosis (ALS) is a synaptopathy accompanied by the presence of cytoplasmic aggregates containing TDP-43, an RNA-binding protein linked to similar to 97% of ALS cases. Using a Drosophila model of ALS, we show that TDP-43 overexpr
Externí odkaz:
http://hdl.handle.net/10150/625980
http://arizona.openrepository.com/arizona/handle/10150/625980
http://arizona.openrepository.com/arizona/handle/10150/625980
Autor:
Keeley, Olivia1,2 (AUTHOR), Coyne, Alyssa N.1,2 (AUTHOR) acoyne3@jhmi.edu
Publikováno v:
Nucleus (1949-1034). Dec2024, Vol. 15 Issue 1, p1-20. 20p.
Autor:
Al-Azzam, Norah, To, Jenny H., Gautam, Vaishali, Street, Lena A., Nguyen, Chloe B., Naritomi, Jack T., Lam, Dylan C., Madrigal, Assael A., Lee, Benjamin, Jin, Wenhao, Avina, Anthony, Mizrahi, Orel, Mueller, Jasmine R., Ford, Willard, Schiavon, Cara R., Rebollo, Elena, Vu, Anthony Q., Blue, Steven M., Madakamutil, Yashwin L., Manor, Uri, Rothstein, Jeffrey D., Coyne, Alyssa N., Jovanovic, Marko, Yeo, Gene W.
Publikováno v:
In Neuron 18 December 2024 112(24):4033-4047
Autor:
Coyne, Alyssa N.
Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease affecting upper and lower motor neurons. Although many cellular processes such as cytoskeletal maintenance and synaptic function are disrupted in ALS, the molecular mechan
Externí odkaz:
http://hdl.handle.net/10150/623181
http://arizona.openrepository.com/arizona/handle/10150/623181
http://arizona.openrepository.com/arizona/handle/10150/623181
Autor:
Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R., Simmons, Zachary, Arcila-Londono, Ximena, Lee, Edward B., Van Deerlin, Vivianna M., Shneider, Neil A., Fraenkel, Ernest, Ostrow, Lyle W., Baas, Frank, Zaitlen, Noah, Berry, James D., Malaspina, Andrea, Fratta, Pietro, Cox, Gregory A., Thompson, Leslie M., Finkbeiner, Steve, Dardiotis, Efthimios, Miller, Timothy M., Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J., Heiman-Patterson, Terry, Hammell, Molly G., Patsopoulos, Nikolaos.A., Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Bowser, Robert, Harms, Matt, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J., Adams, Darius J., Stefanis, Leonidas, Gotkine, Marc, Baloh, Robert H., Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent, Broce, Iris, Drory, Vivian, Ravits, John, McMillan, Corey, Menon, Vilas, Wu, Lani, Altschuler, Steven, Li, Jonathan, Lim, Ryan G., Kaye, Julia A., Dardov, Victoria, Coyne, Alyssa N., Wu, Jie, Milani, Pamela, Cheng, Andrew, Thompson, Terri G., Ornelas, Loren, Frank, Aaron, Adam, Miriam, Banuelos, Maria G., Casale, Malcolm, Cox, Veerle, Escalante-Chong, Renan, Daigle, J. Gavin, Gomez, Emilda, Hayes, Lindsey, Holewenski, Ronald, Lei, Susan, Lenail, Alex, Lima, Leandro, Mandefro, Berhan, Matlock, Andrea, Panther, Lindsay, Patel-Murray, Natasha Leanna, Pham, Jacqueline, Ramamoorthy, Divya, Sachs, Karen, Shelley, Brandon, Stocksdale, Jennifer, Trost, Hannah, Wilhelm, Mark, Venkatraman, Vidya, Wassie, Brook T., Wyman, Stacia, Yang, Stephanie, Van Eyk, Jennifer E., Lloyd, Thomas E., Finkbeiner, Steven, Rothstein, Jeffrey D., Svendsen, Clive N.
Publikováno v:
In iScience 19 November 2021 24(11)
Autor:
Coyne, Alyssa N., Zaepfel, Benjamin L., Hayes, Lindsey, Fitchman, Boris, Salzberg, Yuval, Luo, En-Ching, Bowen, Kelly, Trost, Hannah, Aigner, Stefan, Rigo, Frank, Yeo, Gene W., Harel, Amnon, Svendsen, Clive N., Sareen, Dhruv, Rothstein, Jeffrey D.
Publikováno v:
In Neuron 23 September 2020 107(6):1124-1140
Autor:
Nguyen, Lien, Montrasio, Fabio, Pattamatta, Amrutha, Tusi, Solaleh Khoramian, Bardhi, Olgert, Meyer, Kevin D., Hayes, Lindsey, Nakamura, Katsuya, Banez-Coronel, Monica, Coyne, Alyssa, Guo, Shu, Laboissonniere, Lauren A., Gu, Yuanzheng, Narayanan, Saravanakumar, Smith, Benjamin, Nitsch, Roger M., Kankel, Mark W., Rushe, Mia, Rothstein, Jeffrey, Zu, Tao, Grimm, Jan, Ranum, Laura P.W.
Publikováno v:
In Neuron 19 February 2020 105(4):645-662
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Autor:
Cheng, Weiwei, Wang, Shaopeng, Zhang, Zhe, Morgens, David W., Hayes, Lindsey R., Lee, Soojin, Portz, Bede, Xie, Yongzhi, Nguyen, Baotram V., Haney, Michael S., Yan, Shirui, Dong, Daoyuan, Coyne, Alyssa N., Yang, Junhua, Xian, Fengfan, Cleveland, Don W., Qiu, Zhaozhu, Rothstein, Jeffrey D., Shorter, James, Gao, Fen-Biao, Bassik, Michael C., Sun, Shuying
Publikováno v:
In Neuron 4 December 2019 104(5):885-898