Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Coy, Brunssen"'
Autor:
Heike Brendel, Jennifer Mittag, Anja Hofmann, Helene Hempel, Sindy Giebe, Patrick Diaba-Nuhoho, Steffen Wolk, Christian Reeps, Henning Morawietz, Coy Brunssen
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1178 (2024)
Aim: The primary endothelial NADPH oxidase isoform 4 (NOX4) is notably induced during hypoxia, with emerging evidence suggesting its vasoprotective role through H2O2 production. Therefore, we aimed to elucidate NOX4′s significance in endothelial fu
Externí odkaz:
https://doaj.org/article/665eb58dafb74c9d82a5012dd29931e5
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 503 (2024)
The NADPH oxidase NOX4 that releases H2O2 can mediate vasoprotective mechanisms under pathophysiological conditions in conductive arteries. However, the role of NOX4 in resistance arteries and in perivascular adipose tissue is not well understood. We
Externí odkaz:
https://doaj.org/article/f3617930e57940ff98fb0115f663bf2c
Autor:
Michael Adu-Gyamfi, Claudia Goettsch, Julian Kamhieh-Milz, Lei Chen, Anna Maria Pfefferkorn, Anja Hofmann, Coy Brunssen, Gregor Müller, Thomas Walther, Muhammad Imtiaz Ashraf, Henning Morawietz, Janusz Witowski, Rusan Catar
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 500 (2024)
Endothelin-1 is a key regulator of vascular tone and blood pressure in health and disease. We have recently found that ET-1 production in human microvascular endothelial cells (HMECs) can be promoted by angiotensin II (Ang II) through a novel mechani
Externí odkaz:
https://doaj.org/article/93e54855a4cf439a8fdd4396e9578845
Autor:
Xi Ran, Sabine Müller, Coy Brunssen, Robert Huhle, Martin Scharffenberg, Christian Schnabel, Thea Koch, Marcelo Gama de Abreu, Henning Morawietz, Jorge M. C. Ferreira, Jakob Wittenstein
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background: Mechanical ventilation (MV) is a life supporting therapy but may also cause lung damage. This phenomenon is known as ventilator-induced lung injury (VILI). A potential pathomechanisms of ventilator-induced lung injury may be the stretch-i
Externí odkaz:
https://doaj.org/article/feb974d320a6413b9dd741435a3ddb89
Autor:
Anja Hofmann, Yazan Khorzom, Anna Klimova, Steffen Wolk, Albert Busch, Pamela Sabarstinski, Margarete Müglich, Dmitry Egorov, Irakli Kopaliani, David M. Poitz, Marvin Kapalla, Bianca Hamann, Frieda Frank, Christian Jänichen, Coy Brunssen, Henning Morawietz, Christian Reeps
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 14 (2023)
Background Indication for prophylactic surgical abdominal aortic aneurysm (AAA) repair depends on the maximal aortic diameter. The lectin‐like oxidized low‐density lipoprotein receptor‐1 (LOX‐1) is the major receptor for uptake of oxidized lo
Externí odkaz:
https://doaj.org/article/2964b3e96fb54f1fab2e75398456715b
Autor:
Anja Hofmann, Frieda Frank, Steffen Wolk, Albert Busch, Anna Klimova, Pamela Sabarstinski, Michael Gerlach, Dmitry Egorov, Irakli Kopaliani, Sönke Weinert, Bianca Hamann, David M. Poitz, Coy Brunssen, Henning Morawietz, Katrin Schröder, Christian Reeps
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102473- (2022)
Carotid artery stenosis (CAS) develops from atherosclerotic lesions and plaques. Plaque rupture or stenosis may result in occlusion of the carotid artery. Accordingly, the asymptomatic disease becomes symptomatic, characterized by ischemic stroke or
Externí odkaz:
https://doaj.org/article/84987cca1a354f7a9260c394bd8eca21
Autor:
Shun Hay Pun, Karla M. O’Neill, Kevin S. Edgar, Eleanor K. Gill, Arya Moez, Hojjat Naderi-Meshkin, Sudhir B. Malla, Michelle B. Hookham, Mohammed Alsaggaf, Vinuthna Vani Madishetti, Bianca Botezatu, William King, Coy Brunssen, Henning Morawietz, Philip D. Dunne, Derek P. Brazil, Reinhold J. Medina, Chris J. Watson, David J. Grieve
Publikováno v:
Cells, Vol 12, Iss 18, p 2220 (2023)
Ischaemic cardiovascular disease is associated with tissue hypoxia as a significant determinant of angiogenic dysfunction and adverse remodelling. While cord blood-derived endothelial colony-forming cells (CB-ECFCs) hold clear therapeutic potential d
Externí odkaz:
https://doaj.org/article/c401b027209144cda01f2bdf818f87be
Autor:
Sindy Giebe, Anja Hofmann, Melanie Brux, Frazer Lowe, Damien Breheny, Henning Morawietz, Coy Brunssen
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102150- (2021)
Tobacco smoking and hemodynamic forces are key stimuli for the development of endothelial dysfunction. As an alternative to smoking, next generation tobacco and nicotine products (NGP) are now widely used. However, little is known about their potenti
Externí odkaz:
https://doaj.org/article/28eb7f53b2914088807198dc2bea7fac
Autor:
Anja Hofmann, Bianca Hamann, Anna Klimova, Margarete Müglich, Steffen Wolk, Albert Busch, Frieda Frank, Pamela Sabarstinski, Marvin Kapalla, Josef Albin Nees, Coy Brunssen, David M. Poitz, Henning Morawietz, Christian Reeps
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1753 (2022)
Background: Treatment of cardiovascular risk factors slows the progression of small abdominal aortic aneurysms (AAA). Heme oxygenase-1 (HO-1) is a stress- and hemin-induced enzyme providing cytoprotection against oxidative stress when overexpressed.
Externí odkaz:
https://doaj.org/article/0bf1026255a24febb22a758e9ac32bf3
Autor:
Josephine, Tolkmitt, Heike, Brendel, Birgit, Zatschler, Stefan, Brose, Coy, Brunssen, Irakli, Kopaliani, Andreas, Deussen, Klaus, Matschke, Henning, Morawietz
Publikováno v:
Hormone and Metabolic Research. 55:65-74
Bleeding is a major complication in coronary artery bypass graft surgery. Antifibrinolytic agents like serine protease inhibitor aprotinin can decrease postoperative bleeding and complications of cardiac surgery. However, the effects of aprotinin on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178fb85de43c03fbcfab020a1d797b73
https://doi.org/10.1055/a-1984-0255
https://doi.org/10.1055/a-1984-0255