Simultaneous Quantification of Commonly Used Counter Ions in Peptides and Active Pharmaceutical Ingredients by Mixed Mode Chromatography and Evaporative Light Scattering Detection

Autor: Streuli, Alessandro, Coxon, Christopher R., Steuer, Christian

Publikováno v: In Journal of Pharmaceutical Sciences August 2021 110(8):2997-3003

The Inclusion of a Matrix Metalloproteinase-9 Responsive Sequence in Self-assembled Peptide-based Brain-Targeting Nanoparticles Improves the Efficiency of Nanoparticles Crossing the Blood-Brain Barrier at Elevated MMP-9 Levels

Autor: Islam, Yamir, Ehtezazi, Parinaz, Cashmore, Andrew, Marinsalda, Elena, Leach, Andrew G., Coxon, Christopher R., Fatokun, Amos A., Sexton, Darren W., Khan, Iftikhar, Zouganelis, Georgios, Downing, James, Pluchino, Stefano, Sivakumaran, Muttuswamy, Teixido, Meritxell, Ehtezazi, Touraj

Publikováno v: In Journal of Pharmaceutical Sciences March 2021 110(3):1349-1364

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Perfluoroaryl and Perfluoroheteroaryl Reagents as Emerging New Tools for Peptide Synthesis, Modification and Bioconjugation.

Autor: Brittain, William D. G.¹ (AUTHOR) william.d.brittain@durham.ac.uk, Coxon, Christopher R.² (AUTHOR) chris.coxon@ed.ac.uk

Publikováno v: Chemistry - A European Journal. 2/1/2022, Vol. 28 Issue 7, p1-14. 14p.

5,10,15,20‐Tetrakis(pentafluorophenyl)porphyrin as Functional Platform for Peptide Stapling and Multicyclisation

Autor: Dognini, Paolo, Chaudhry, Talhat, Scagnetti, Giulia, Assante, Michele, Hanson, George s. m., Ross, Kehinde, Giuntini, Francesca, Coxon, Christopher r.

Publikováno v: Dognini, P, Chaudhry, T, Scagnetti, G, Assante, M, Hanson, G S M, Ross, K, Giuntini, F & Coxon, C R 2023, ' 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin as Functional Platform for Peptide Stapling and Multicyclisation ', Chemistry – A European Journal . https://doi.org/10.1002/chem.202301410

Polyfluorinated aromatic reagents readily react with thiolates via nucleophilic aromatic substitution (SNAr) and provide excellent scaffolds for peptide cyclisation. Here we report a robust and versatile platform for peptide stapling and multicyclisa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::f085b029da9eeb4b32465e0e5ef180b2
https://hdl.handle.net/20.500.11820/528f6ae8-bfcc-44c4-b1a0-d53acbab204e