Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy

Autor: Patrício, Maria I., Cox, Christopher I., Blue, Clare, Barnard, Alun R., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E.

Publikováno v: In Molecular Therapy - Methods & Clinical Development 12 June 2020 17:99-106

The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A

Autor: Patrício, Maria I., Barnard, Alun R., Cox, Christopher I., Blue, Clare, MacLaren, Robert E.

Publikováno v: In Molecular Therapy - Methods & Clinical Development 15 June 2018 9:288-295

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Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy.

Autor: Patrício MI; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Cox CI; Nightstar Therapeutics, 10 Midford Place, London, UK., Blue C; Nightstar Therapeutics, 10 Midford Place, London, UK., Barnard AR; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Martinez-Fernandez de la Camara C; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., MacLaren RE; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2019 Nov 20; Vol. 17, pp. 99-106. Date of Electronic Publication: 2019 Nov 20 (Print Publication: 2020).