Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Cowley SA"'
Autor:
Washer, SJ, Perez-Alcantara, M, Chen, Y, Steer, J, James, WS, Trynka, G, Bassett, AR, Cowley, SA
There is increasing genetic evidence for the role of microglia in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and motor neuron disease. Therefore, there is a need to generate authentic in vitro models to study human microglial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb31a2c5d8c7f4ff375d78155edde807
https://ora.ox.ac.uk/objects/uuid:e2d1185c-c668-4d2b-ae83-ae65c77c492a
https://ora.ox.ac.uk/objects/uuid:e2d1185c-c668-4d2b-ae83-ae65c77c492a
Autor:
Hanrath, AT, Hatton, CF, Gothe, F, Browne, C, Vowles, J, Leary, P, Cockell, SJ, Cowley, SA, James, WS, Hambleton, S, Duncan, CJA
Publikováno v:
Frontiers in Immunology. 13
Macrophages are key target cells of Zika virus (ZIKV) infection, implicated as a viral reservoir seeding sanctuary sites such as the central nervous system and testes. This rests on the apparent ability of macrophages to sustain ZIKV replication with
Autor:
Connor-Robson, N, Booth, H, Martin, JG, Gao, B, Li, K, Doig, N, Vowles, J, Browne, C, Klinger, L, Juhasz, P, Klein, C, Cowley, SA, Bolam, P, Hirst, W, Wade-Martins, R
Publikováno v:
Neurobiology of Disease, Vol 127, Iss, Pp 512-526 (2019)
Neurobiology of Disease
Neurobiology of Disease
Background Mutations in LRRK2 are the most common cause of autosomal dominant Parkinson's disease, and the relevance of LRRK2 to the sporadic form of the disease is becoming ever more apparent. It is therefore essential that studies are conducted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b7268c281d6c7f4627e2a8bb7ba71182
https://orca.cardiff.ac.uk/id/eprint/142163/1/1-s2.0-S0969996119300968-main.pdf
https://orca.cardiff.ac.uk/id/eprint/142163/1/1-s2.0-S0969996119300968-main.pdf
Autor:
Zambon, F, Cherubini, M, Fernandes, HJR, Lang, C, Ryan, BJ, Volpato, V, Bengoa-Vergniory, N, Vingill, S, Attar, M, Booth, HDE, Haenseler, W, Vowles, J, Bowden, R, Webber, C, Cowley, SA, Wade-Martins, R
Publikováno v:
Human Molecular Genetics
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and a central role for α-synuclein (αSyn; SNCA) in disease aetiology has been proposed based on genetics and neuropathology. To better understand the pathological mecha
Autor:
Watson, LM, Smith, DC, Raimondo, JV, Burman, RJ, Ballo, R, Scholefield, J, Tyers, L, Cowley, SA, Wood, MJA, Kidson, SH, Greenberg, LJ
Spinocerebellar ataxia type 7 (SCA7) is an inherited neurodegenerative disease that is characterised by ataxia and visual loss. It results from a degeneration of cerebellar Purkinje neurons and retinal photoreceptors caused by a polyglutamine repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::dcffe590beb271669bf4801844f30fa0
Publikováno v:
Biochemical Pharmacology
Graphical abstract
Phagocytosis of pathogens, apoptotic cells and debris is a key feature of macrophage function in host defense and tissue homeostasis. Quantification of macrophage phagocytosis in vitro has traditionally been technically challe
Phagocytosis of pathogens, apoptotic cells and debris is a key feature of macrophage function in host defense and tissue homeostasis. Quantification of macrophage phagocytosis in vitro has traditionally been technically challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6eae0b0f2b07057c2ddd419cb99e1015
https://ora.ox.ac.uk/objects/uuid:8d784f7b-bed6-452b-96ed-7746fe3b6a04
https://ora.ox.ac.uk/objects/uuid:8d784f7b-bed6-452b-96ed-7746fe3b6a04
Autor:
Dafinca, R, Scaber, J, Ababneh, N, Lalic, T, Weir, G, Christian, H, Vowles, J, Douglas, AGL, Fletcher-Jones, A, Browne, C, Nakanishi, M, Turner, MR, Wade-Martins, R, Cowley, SA, Talbot, K
An expanded hexanucleotide repeat in a noncoding region of the C9orf72 gene is a major cause of amyotrophic lateral sclerosis (ALS), accounting for up to 40andpercnt; of familial cases and 7andpercnt; of sporadic ALS in European populations. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d416e5b68c0fbd02aa724deb92296115
https://eprints.soton.ac.uk/393755/
https://eprints.soton.ac.uk/393755/
Publikováno v:
Journal of Advanced Nursing (Wiley-Blackwell); Mar1996, Vol. 23 Issue 3, p512-520, 9p
Publikováno v:
Journal of Bone and Joint Surgery - British Volume; September 1990, Vol. 72 Issue: 5 p874-880, 7p
Publikováno v:
Retrovirology, Vol 8, Iss Suppl 2, p O3 (2011)
Externí odkaz:
https://doaj.org/article/833645ff81f34175beb3f6cb7d5bc5cf