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Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.
Autor:
Rupani DN; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Thege FI; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Chandra V; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Rajaei H; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Cowan RW; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Gastroenterology, Hepatology & Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Wörmann SM; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Le Roux O; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Malaney P; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Manning SL; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Gastroenterology, Hepatology & Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Hashem J; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Gastroenterology, Hepatology & Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Bailey-Lundberg J; Department of Anesthesiology, Center for Perioperative Medicine, McGovern Medical School, The University of Texas Health Sciences Center, Houston, TX 77030, USA.; Center for Interventional Gastroenterology at UTHealth (iGUT), McGovern Medical School, Houston, TX 77030, USA., Rhim AD; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Gastroenterology, Hepatology & Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., McAllister F; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Publikováno v:
Development (Cambridge, England) [Development] 2023 Jan 15; Vol. 150 (2). Date of Electronic Publication: 2023 Jan 16.
Autor:
Wörmann SM; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. smwoermann@mdanderson.org.; Department of Translational Molecular Pathology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. smwoermann@mdanderson.org., Zhang A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Thege FI; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.; Department of Translational Molecular Pathology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Cowan RW; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Rupani DN; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Wang R; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Manning SL; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Gates C; BRCF Bioinformatics Core, University of Michigan, School of Medicine, Ann Arbor, MI, USA., Wu W; BRCF Bioinformatics Core, University of Michigan, School of Medicine, Ann Arbor, MI, USA., Levin-Klein R; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN, USA., Rajapakshe KI; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Yu M; Department of Experimental Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Multani AS; Department of Genetics, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Kang Y; Department of Surgical Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Taniguchi CM; Department of Experimental Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Schlacher K; Department of Cancer Biology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Bellin MD; University of Minnesota Medical Center, Schulze Diabetes Institute, Minneapolis, MN, USA., Katz MHG; Department of Surgical Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Kim MP; Department of Surgical Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Fleming JB; Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Gallinger S; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Maddipati R; Department of Internal Medicine and Hamon Center for Therapeutic Oncology Research and Children's Research Institute, UT Southwestern Medical Center, Dallas, TX, USA., Harris RS; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN, USA.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, Minnesota, USA., Notta F; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Ross SR; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Maitra A; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.; Department of Translational Molecular Pathology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Rhim AD; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. arhim@mdanderson.org.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. arhim@mdanderson.org.
Publikováno v:
Nature cancer [Nat Cancer] 2021 Dec; Vol. 2 (12), pp. 1338-1356. Date of Electronic Publication: 2021 Nov 18.
Autor:
Cowan RW; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA., Pratt ED; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA., Kang JM; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA., Zhao J; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.; Department of Translational Molecular Pathology, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA., Wilhelm JJ; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Surgery, Schulze Diabetes Institute, University of Minnesota, Minneapolis, Minnesota, USA., Abdulla M; Department of Surgery, Schulze Diabetes Institute, University of Minnesota, Minneapolis, Minnesota, USA., Qiao EM; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Brennan LP; University of Michigan Medical School, Ann Arbor, Michigan, USA., Ulintz PJ; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.; BRCF Bioinformatics Core, University of Michigan, Ann Arbor, Michigan, USA., Bellin MD; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Department of Surgery, Schulze Diabetes Institute, University of Minnesota, Minneapolis, Minnesota, USA., Rhim AD; Ahmed Cancer Center for Pancreatic Cancer Research, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.; Department of Gastroenterology, Hepatology & Nutrition, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.
Publikováno v:
Clinical and translational gastroenterology [Clin Transl Gastroenterol] 2021 Nov 18; Vol. 12 (11), pp. e00431. Date of Electronic Publication: 2021 Nov 18.
Autor:
Pratt ED; Ahmed Center for Pancreatic Cancer Research, Department of Gastroenterology, Hepatology and Nutrition , University of Texas MD Anderson Cancer Center , Houston , Texas , United States., Cowan RW; Ahmed Center for Pancreatic Cancer Research, Department of Gastroenterology, Hepatology and Nutrition , University of Texas MD Anderson Cancer Center , Houston , Texas , United States., Manning SL; Ahmed Center for Pancreatic Cancer Research, Department of Gastroenterology, Hepatology and Nutrition , University of Texas MD Anderson Cancer Center , Houston , Texas , United States., Qiao E, Cameron H, Schradle K, Simeone DM, Zhen DB
Publikováno v:
Analytical chemistry [Anal Chem] 2019 Jun 18; Vol. 91 (12), pp. 7516-7523. Date of Electronic Publication: 2019 May 24.
Autor:
Kopp JL; Departments of Pediatrics and Cellular and Molecular Medicine, University of California-San Diego, La Jolla, California; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Dubois CL; Departments of Pediatrics and Cellular and Molecular Medicine, University of California-San Diego, La Jolla, California., Schaeffer DF; Department of Pathology and Laboratory and Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Samani A; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Taghizadeh F; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Cowan RW; Ahmed Center for Pancreatic Cancer Research and Department of Gastroenterology, Hepatology and Nutrition, University of Texas M.D. Anderson Cancer Center, Houston, Texas., Rhim AD; Ahmed Center for Pancreatic Cancer Research and Department of Gastroenterology, Hepatology and Nutrition, University of Texas M.D. Anderson Cancer Center, Houston, Texas., Stiles BL; Department of Pharmaceutical Sciences, School of Pharmacy, Keck School of Medicine, University of Southern California, and the Norris Comprehensive Cancer Center, Los Angeles, California., Valasek M; Department of Pathology, University of California-San Diego, La Jolla, California., Sander M; Departments of Pediatrics and Cellular and Molecular Medicine, University of California-San Diego, La Jolla, California. Electronic address: masander@ucsd.edu.
Publikováno v:
Gastroenterology [Gastroenterology] 2018 Apr; Vol. 154 (5), pp. 1509-1523.e5. Date of Electronic Publication: 2017 Dec 19.
Autor:
Cowan RW; Division of Gastroenterology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan., Maitra A; Departments of Pathology and Translational Molecular Pathology, Sheikh Ahmed Pancreatic Cancer Research Center, University of Texas MD Anderson Cancer Center, Houston, Texas., Rhim AD; Division of Gastroenterology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan. Electronic address: arhim@med.umich.edu.
Publikováno v:
Gastroenterology [Gastroenterology] 2015 Dec; Vol. 149 (7), pp. 1685-8. Date of Electronic Publication: 2015 Oct 23.
Autor:
Salahudeen AA; Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX., Gupta A; Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX., Jones JC; Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX., Cowan RW; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Vusirikala M; Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX; Simmons Cancer Center, Division of Medical Oncology, University of Texas Southwestern Medical Center, Dallas, TX., Kwong C; Simmons Cancer Center, Division of Medical Oncology, University of Texas Southwestern Medical Center, Dallas, TX., Naina HV; Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX; Simmons Cancer Center, Division of Medical Oncology, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: harris.naina@utsouthwestern.edu.
Publikováno v:
Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2015 Sep; Vol. 15 (9), pp. e137-40. Date of Electronic Publication: 2015 Jun 19.