Symptom profile, case and symptom clustering, clinical and demographic characteristics of a multicentre cohort of 1297 patients evaluated for Long-COVID

Autor: Marco Floridia, Marina Giuliano, Liliana Elena Weimer, Maria Rosa Ciardi, Piergiuseppe Agostoni, Paolo Palange, Patrizia Rovere Querini, Silvia Zucco, Matteo Tosato, Aldo Lo Forte, Paolo Bonfanti, Donato Lacedonia, Emanuela Barisione, Stefano Figliozzi, Paola Andreozzi, Cecilia Damiano, Flavia Pricci, Graziano Onder, the I. S. S. Long-COVID Study Group

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)

Abstract Background Long-COVID symptoms remain incompletely defined due to a large heterogeneity in the populations studied, case definitions, and settings of care. The aim of this study was to assess, in patients accessing care for Long-COVID, the p

Externí odkaz: https://doaj.org/article/27a513781e7b40259d6402f4e44219a0

Pediatric suicide attempts lagged during the COVID-19 pandemic: a European multicenter study

Autor: Ana Moscoso, Anthony Cousien, Giulia Serra, Annette Erlangsen, Mar Vila, Ljubica Paradžik, Sandra Pires, Francisco Villar, Marija Bogadi, Pedro Caldeira da Silva, Stefano Vicari, Mette Falkenberg Krantz, Richard Delorme, & the ACE-COVID study group

Publikováno v: Child and Adolescent Psychiatry and Mental Health, Vol 18, Iss 1, Pp 1-12 (2024)

Abstract Background Elevated rates of suicidal behavior were reported during the COVID-19 pandemic. However, information is scarce on patients’ profiles during this period. Studies evoke the potential adverse effects of the mandatory lockdown, but

Externí odkaz: https://doaj.org/article/e8c19c26e028493abb186e38af6fbdad

Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

Autor: Yun Shan Goh, Siew-Wai Fong, Matthew Zirui Tay, Angeline Rouers, Zi Wei Chang, Jean-Marc Chavatte, Pei Xiang Hor, Chiew Yee Loh, Yuling Huang, Yong Jie Tan, Bei Wang, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Raphael Tze Chuen Lee, Georgina Lim, NCID Study Group, COVID-Study Group, Sebastian Maurer-Stroh, Cheng-I Wang, Yee‐Sin Leo, Raymond T. P. Lin, Meng Chon Lam, David C. Lye, Barnaby Edward Young, Lisa F. P. Ng, Laurent Renia

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)

Abstract Identification of the risk factors and the high-risk groups which are most vulnerable is critical in COVID-19 disease management at a population level. Evaluating the efficacy of vaccination against infections is necessary to determine boost

Externí odkaz: https://doaj.org/article/fca10ae838194a84adcc6ba332be6ca8

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Autor: Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jeremy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, Hassan Abolhassani, Ahmad Abou Tayoun, Alessandro Aiuti, Ilad Alavi Darazam, Luis M. Allende, Rebeca Alonso-Arias, Andrés Augusto Arias, Gokhan Aytekin, Peter Bergman, Simone Bondesan, Yenan T. Bryceson, Ingrid G. Bustos, Oscar Cabrera-Marante, Sheila Carcel, Paola Carrera, Giorgio Casari, Khalil Chaïbi, Roger Colobran, Antonio Condino-Neto, Laura E. Covill, Ottavia M. Delmonte, Loubna El Zein, Carlos Flores, Peter K. Gregersen, Marta Gut, Filomeen Haerynck, Rabih Halwani, Selda Hancerli, Lennart Hammarström, Nevin Hatipoğlu, Adem Karbuz, Sevgi Keles, Christèle Kyheng, Rafael Leon-Lopez, Jose Luis Franco, Davood Mansouri, Javier Martinez-Picado, Ozge Metin Akcan, Isabelle Migeotte, Pierre-Emmanuel Morange, Guillaume Morelle, Andrea Martin-Nalda, Giuseppe Novelli, Antonio Novelli, Tayfun Ozcelik, Figen Palabiyik, Qiang Pan-Hammarström, Rebeca Pérez de Diego, Laura Planas-Serra, Daniel E. Pleguezuelo, Carolina Prando, Aurora Pujol, Luis Felipe Reyes, Jacques G. Rivière, Carlos Rodriguez-Gallego, Julian Rojas, Patrizia Rovere-Querini, Agatha Schlüter, Mohammad Shahrooei, Ali Sobh, Pere Soler-Palacin, Yacine Tandjaoui-Lambiotte, Imran Tipu, Cristina Tresoldi, Jesus Troya, Diederik van de Beek, Mayana Zatz, Pawel Zawadzki, Saleh Zaid Al-Muhsen, Mohammed Faraj Alosaimi, Fahad M. Alsohime, Hagit Baris-Feldman, Manish J. Butte, Stefan N. Constantinescu, Megan A. Cooper, Clifton L. Dalgard, Jacques Fellay, James R. Heath, Yu-Lung Lau, Richard P. Lifton, Tom Maniatis, Trine H. Mogensen, Horst von Bernuth, Alban Lermine, Michel Vidaud, Anne Boland, Jean-François Deleuze, Robert Nussbaum, Amanda Kahn-Kirby, France Mentre, Sarah Tubiana, Guy Gorochov, Florence Tubach, Pierre Hausfater, COVID Human Genetic Effort, COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID-STORM Clinicians, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, Isabelle Meyts, Shen-Ying Zhang, Anne Puel, Luigi D. Notarangelo, Stephanie Boisson-Dupuis, Helen C. Su, Bertrand Boisson, Emmanuelle Jouanguy, Jean-Laurent Casanova, Qian Zhang, Laurent Abel, Aurélie Cobat

Publikováno v: Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)

Abstract Background We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15–20% of cases of life-threatening

Externí odkaz: https://doaj.org/article/86e4db2aa39842caa8f2f5c9e6d95290

Convalescent or standard plasma versus standard of care in the treatment of COVID-19 patients with respiratory impairment: short and long-term effects. A three-arm randomized controlled clinical trial

Autor: Paola Maria Manzini, Giovannino Ciccone, Francesco Giuseppe De Rosa, Rossana Cavallo, Valeria Ghisetti, Sergio D’Antico, Claudia Galassi, Fabio Saccona, Anna Castiglione, Nadia Birocco, Tiziana Francisci, Huijing Hu, Clara Pecoraro, Franca Danielle, Luciana Labanca, Anna Maria Bordiga, Marco Lorenzi, Giovanni Camisasca, Osvaldo Giachino, Mauro Pagliarino, Piero Ottone, Ilvana Tiziana Donatella Scuvera, Roberto Guaschino, Roberto Freilone, Pierluigi Berti, Fabrizia Pittaluga, Maria Avolio, Cristina Costa, Samuele Raso, Aurora Nucci, Massimo Milan, Alessandra Baffa, Alessandra Russo, Antonella Tornello, Laura Maddalena, Grazia Delios, Fabio Paolo Marletto, Anna Grazia De Micheli, Alessio Mattei, Stefano Baldassano, Francesca Canta, Maria Luisa Russo, Daniele Bergamo, Francesco Vitale, Marco Maria Liccardi, Alessandra Chinaglia, Andrea Calcagno, Marcella Converso, Chiara Aldieri, Valentina Libanore, Ilaria Blangetti, Valentina Benedetti, Barbara Mitola, Gitana Scozzari, the PLACO COVID Study Group

Publikováno v: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-14 (2022)

Abstract Background The efficacy of early treatment with convalescent plasma in patients with COVID-19 is debated. Nothing is known about the potential effect of other plasma components other than anti-SARS-CoV-2 antibodies. Methods To determine whet

Externí odkaz: https://doaj.org/article/e0cc3da5a92e46c6b468d643c3016ec9