Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Covadonga Martín Sánchez"'
Autor:
Diego Gómez-Coronado, Rebeca Busto, Miguel A. Lasunción, Covadonga Martín-Sánchez, Javier Martínez-Botas
Publikováno v:
Biochemical pharmacology. 196
The mevalonate pathway is responsible for the synthesis of isoprenoids, including sterols and other metabolites that are essential for diverse biological functions. Cholesterol, the main sterol in mammals, and non-sterol isoprenoids are in high deman
Autor:
Paloma Fernández Freire, Miguel A. Lasunción, Lidia Daimiel, M.J. Hazen, José Manuel Pérez Martín, Javier Martínez-Botas, Ana Peropadre, Covadonga Martín Sánchez
Publikováno v:
Food and Chemical Toxicology. 72:195-203
Butylated hydroxyanisole and propylparaben are phenolic preservatives commonly used in food, pharmaceutical and personal care products. Both chemicals have been subjected to extensive toxicological studies, due to the growing concern regarding their
Publikováno v:
Current Opinion in Pharmacology. 12:717-723
Mammalian cells require cholesterol for proliferation. Cholesterol contributes not only to the physicochemical properties of membranes but also to the organization of lipid rafts involved in signal transduction. Inhibition of cholesterol biosynthesis
Autor:
Javier Martínez-Botas, Covadonga Martín Sánchez, Jong-Sik Jin, Gema de la Peña, Miguel A. Lasunción, M.J. Hazen, Yajaira Suárez, Wei Zhang, José Manuel Pérez Martín, Sara Rodríguez-Acebes, Alberto Dávalos, Diego Gómez-Coronado, Yung-Chi Cheng, Rebeca Busto
Publikováno v:
Biochimica et biophysica acta. 1851(9)
The mevalonate pathway is tightly linked to cell division. Mevalonate derived non-sterol isoprenoids and cholesterol are essential for cell cycle progression and mitosis completion respectively. In the present work, we studied the effects of fluorome
Autor:
Covadonga Martín-Sánchez, Carolina C. Sánchez-Martín, Carlos Fernández-Hernando, Gema de la Peña, Miguel A. Lasunción, Alberto Dávalos
Publikováno v:
Cancer research. 67(7)
Cholesterol metabolism is particularly active in malignant, proliferative cells, whereas cholesterol starvation has been shown to inhibit cell proliferation. Inhibition of enzymes involved in cholesterol biosynthesis at steps before the formation of
Autor:
Covadonga Martín-Sánchez, Carolina C. Sánchez-Martín, G. de la Pena, Miguel A. Lasunción, Alberto Dávalos, P. Castilla
Publikováno v:
Atherosclerosis Supplements. 8:61-62