A combined evolutionary and structural approach to disclose the primary structural determinants essential for proneurotrophins biological functions

Autor: Covaceuszach, S., Peche, L.Y., Konarev, P.V., Lamba, D.

Publikováno v: In Computational and Structural Biotechnology Journal 2021 19:2891-2904

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

A dystroglycan mutation (p.Cys66uPhe) associated to muscle-eye-brain disease with multicystic leukodystrophy results in ER-retention of the mutant protein

Autor: Signorino G (1), Covaceuszach S (2), Bozzi M (1), (3), Hübner W (4), Mönkemöller V (4), Konarev PV (5), Cassetta A (2), Brancaccio A (3), (6), Sciandra F (3).

Publikováno v: Human mutation 39 (2018): 266–280.
info:cnr-pdr/source/autori:Signorino G (1), Covaceuszach S (2), Bozzi M (1),(3), Hübner W (4), Mönkemöller V (4), Konarev PV (5), Cassetta A (2), Brancaccio A (3),(6), Sciandra F (3)./titolo:A dystroglycan mutation (p.Cys66uPhe) associated to muscle-eye-brain disease with multicystic leukodystrophy results in ER-retention of the mutant protein/doi:/rivista:Human mutation/anno:2018/pagina_da:266/pagina_a:280/intervallo_pagine:266–280/volume:39

Dystroglycan (DG) is a cell adhesion complex composed by two subunits, the highly glycosylated ?-DG and the transmembrane ?-DG. In skeletal muscle, DG is involved in dystroglycanopathies, a group of heterogeneous muscular dystrophies characterized by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::adbed9846b9650783ff2d45322dc2d02
http://www.cnr.it/prodotto/i/390142

Structural flexibility of human α-dystroglycan

Autor: Covaceuszach, S., Bozzi, M., Bigotti, M.G., Sciandra, F., Konarev, P.V., Brancaccio, A., Cassetta, A.

Publikováno v: Covaceuszach, S, Bozzi, M, Bigotti, M G, Sciandra, F, Konarev, P V, Brancaccio, A & Cassetta, A 2017, ' Structural flexibility of human α-dystroglycan ', FEBS Open Bio, vol. 7, no. 8, pp. 1064-1077 . https://doi.org/10.1002/2211-5463.12259
'FEBS Open Bio ', vol: 7, pages: 1064-1077 (2017)

Dystroglycan (DG), composed of α and β subunits, belongs to the dystrophin-associated glycoprotein complex. α-DG is an extracellular matrix protein that undergoes a complex post-translational glycosylation process. The bifunctional glycosyltransfe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8f0b5b31ab8d4c68ad2e07ef956b62f4
https://hdl.handle.net/1983/ca0dcb65-e93d-44e3-b4c3-63f1a4a020c6

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.