Zobrazeno 1 - 10
of 159
pro vyhledávání: '"CovR"'
Autor:
Sophia Liu, Yuetian Yan, Cody M. Secor, Zachary R. Oberholtzer, Donna J. Skow, Mushhood Sheikh, Youmi Moon, Yue Fu, Cristinel Sandu, Shunhai Wang, Ning Li, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTCo-formulation of multiple drug products is an efficient and convenient approach to simultaneously deliver multiple biotherapeutics with the potentially added benefit of a synergistic therapeutic effect. However, co-formulation also increases
Externí odkaz:
https://doaj.org/article/1494bc863c804d3eb9523d2ed2f12fcb
Autor:
Lea A. Tölken, Antje D. Paulikat, Lana H. Jachmann, Alexander Reder, Manuela Gesell Salazar, Laura M. Palma Medina, Stephan Michalik, Uwe Völker, Mattias Svensson, Anna Norrby-Teglund, Katharina J. Hoff, Michael Lammers, Nikolai Siemens
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-17 (2024)
Abstract Background Streptococcus pyogenes (group A streptococcus, GAS) causes a variety of diseases ranging from mild superficial infections of the throat and skin to severe invasive infections, such as necrotizing soft tissue infections (NSTIs). Ti
Externí odkaz:
https://doaj.org/article/8cfa48c1af2241b6be605e7677b877f0
Publikováno v:
BMC Veterinary Research, Vol 19, Iss 1, Pp 1-15 (2023)
Abstract Background Streptococcus suis serotype 2 (S. suis 2) is an important zoonotic pathogen. Orphan response regulator CovR plays crucial regulative functions in the survivability and pathogenicity of S. suis 2. However, research on the CovR in S
Externí odkaz:
https://doaj.org/article/f81b8c97f4d0487aad0c0ce0ec283401
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
The deletion of orphan response regulator CovR reduces the growth rate of Streptococcus suis serotype 2 (S. suis 2). In this study, metabolome and transcriptome profiling were performed to study the mechanisms underlying the poor growth of S. suis 2
Externí odkaz:
https://doaj.org/article/a8e73539b21d4c78b44590ffb297060b
Autor:
Emma L. Langshaw, Simone Reynolds, Victoria Ozberk, Jessica Dooley, Ainslie Calcutt, Mehfuz Zaman, Mark J. Walker, Michael R. Batzloff, Mark R. Davies, Michael F. Good, Manisha Pandey
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Mutation within the Streptococcus pyogenes (Streptococcus group A; Strep A) covR/S regulatory system has been associated with a hypervirulent phenotype resulting from the upregulation of several virulence factors, including the pore-forming
Externí odkaz:
https://doaj.org/article/f1d1a8111f9c42cc991b8d58bf71c93d
Akademický článek
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Autor:
Yong-An Shi, Tzu-Ching Chen, Yan-Wen Chen, Yen-Shan Liu, Yi-Ywan M. Chen, Chih-Ho Lai, Cheng-Hsun Chiu, Chuan Chiang-Ni
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Necrotizing fasciitis is a severe infectious disease that results in significant mortality. Streptococcus pyogenes (group A Streptococcus, GAS) is one of the most common bacterial pathogens of monomicrobial necrotizing fasciitis. The early d
Externí odkaz:
https://doaj.org/article/bfd3a0b5140f44b3a6dbb1f790620a48
Autor:
Yuhao Dong, Ke Ma, Qing Cao, Hao Huang, Meng Nie, Guangjin Liu, Mingguo Jiang, Chengping Lu, Yongjie Liu
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 2113-2124 (2021)
The clustered regularly interspaced palindromic repeats (CRISPR)-Cas (CRISPR-associated) system is a prokaryotic defence against invading mobile genetic elements, such as bacteriophages or exogenous plasmids. Beyond this, this system has been shown t
Externí odkaz:
https://doaj.org/article/79bbd0bc957f4f74aa8f0fc95ac28457
Autor:
Chuan Chiang-Ni, Yen-Shan Liu, Chieh-Yu Lin, Chih-Yun Hsu, Yong-An Shi, Yi-Ywan M. Chen, Chih-Ho Lai, Cheng-Hsun Chiu
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The acquisition of the phage-encoded superantigen ssa by scarlet fever-associated group A Streptococcus (Streptococcus pyogenes, GAS) is found in North Asia. Nonetheless, the impact of acquiring ssa by GAS in invasive infections is unclear. This stud
Externí odkaz:
https://doaj.org/article/3bf29c747c9f46499130fbea2f710eab
Akademický článek
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