Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Courtney W. Hanna"'
Autor:
Jake R. Thomas, Anna Appios, Emily F. Calderbank, Nagisa Yoshida, Xiaohui Zhao, Russell S. Hamilton, Ashley Moffett, Andrew Sharkey, Elisa Laurenti, Courtney W. Hanna, Naomi McGovern
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The generation of primitive macrophages remains a poorly understood process in humans. Here, the authors identify placental erythro-myeloid progenitors that give rise to foetal macrophages in the early human placenta and demonstrate that epigenetic s
Externí odkaz:
https://doaj.org/article/370741294d1d45e496cf44e8daffe8d6
Autor:
Simon Andrews, Christel Krueger, Maravillas Mellado-Lopez, Myriam Hemberger, Wendy Dean, Vicente Perez-Garcia, Courtney W. Hanna
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
DNA methylation is a repressive modification that is essential for development. Here the authors reveal a critical role for DNA methylation in placental development during pregnancy. Failure to properly establish placental DNA methylation patterns co
Externí odkaz:
https://doaj.org/article/01d5556441ef4bbcbc1a30a3c4fa2e0a
Autor:
Courtney W. Hanna, Raquel Pérez-Palacios, Lenka Gahurova, Michael Schubert, Felix Krueger, Laura Biggins, Simon Andrews, Maria Colomé-Tatché, Deborah Bourc’his, Wendy Dean, Gavin Kelsey
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background Genomic imprinting is an epigenetic phenomenon that allows a subset of genes to be expressed mono-allelically based on the parent of origin and is typically regulated by differential DNA methylation inherited from gametes. Imprint
Externí odkaz:
https://doaj.org/article/1f13e69e51574ec4ae0c64c683c949cc
Autor:
Gintarė Sendžikaitė, Courtney W. Hanna, Kathleen R. Stewart-Morgan, Elena Ivanova, Gavin Kelsey
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
PWWP domains of DNMT3A and DNMT3B are proposed to interact with H3K36me3. Here the authors present a mouse model carrying a D329A point mutation in the DNMT3A PWWP domain and find this causes dominant postnatal growth retardation, with aberrant progr
Externí odkaz:
https://doaj.org/article/bf208415af2e4e6986d414cb8d984ae3
Autor:
Courtney W Hanna
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008709 (2020)
As the maternal-foetal interface, the placenta is essential for the establishment and progression of healthy pregnancy, regulating both foetal growth and maternal adaptation to pregnancy. The evolution and functional importance of genomic imprinting
Externí odkaz:
https://doaj.org/article/8eaadad4cf3346799a5b24b0feff2e15
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-16 (2018)
Abstract Background 5,10-Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in one-carbon metabolism that ensures the availability of methyl groups for methylation reactions. Two single-nucleotide polymorphisms (SNPs) in the MTHFR gene, 677C
Externí odkaz:
https://doaj.org/article/25b6b22c9289462c8f3e8586b13de382
Autor:
Courtney W. Hanna, Gavin Kelsey
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-4 (2017)
Abstract Inheritance of DNA methylation states from gametes determines genomic imprinting in mammals. A new study shows that repressive chromatin in oocytes can also confer imprinting.
Externí odkaz:
https://doaj.org/article/db991cb3514b4e1898628dee31a5fc77
Autor:
Hannah Demond, Courtney W. Hanna, Juan Castillo-Fernandez, Fátima Santos, Evangelia K. Papachristou, Anne Segonds-Pichon, Kamal Kishore, Simon Andrews, Clive S. D'Santos, Gavin Kelsey
EHMT1 (also known as GLP) is a multifunctional protein, best known for its role as an H3K9me1 and H3K9me2 methyltransferase through its reportedly obligatory dimerization with EHMT2 (also known as G9A). Here, we investigated the role of EHMT1 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf521f8f1851c8c3e0800ef07278de6
Autor:
Courtney W Hanna, Jiahao Huang, Christian Belton, Susanne Reinhardt, Andreas Dahl, Simon Andrews, A Francis Stewart, Andrea Kranz, Gavin Kelsey
Publikováno v:
Nucleic Acids Research. 50:1993-2004
Funder: FP7 People: Marie-Curie Actions; Grant(s): 290123
Histone 3 lysine 4 trimethylation (H3K4me3) is an epigenetic mark found at gene promoters and CpG islands. H3K4me3 is essential for mammalian development, yet mechanisms underlying its ge
Histone 3 lysine 4 trimethylation (H3K4me3) is an epigenetic mark found at gene promoters and CpG islands. H3K4me3 is essential for mammalian development, yet mechanisms underlying its ge
Autor:
Nobuyoshi Akimitsu, Marina Alexeeva, Juliana Almeida, Rodolfo Daniel Ávila-Avilés, Jérémy Berthelier, Akanksha Bhatnagar, Maria Boskovic, Nancy V.N. Carullo, J. Armando Casas-Mollano, Frances A. Champagne, Taiping Chen, Ravindresh Chhabra, James P. Curley, Gareth W. Davison, Gary L. Dunbar, Thomas Eggermann, Felice Elefant, Peter D. Fransquet, Hodaka Fujii, Toshitsugu Fujita, Leonardo Furci, Jose Garcia, Balaram Ghosh, Linn Gillberg, Karen Giménez-Orenga, Courtney W. Hanna, Zdenko Herceg, J. Manuel Hernández-Hernández, Line Hjort, Xiaotong Hu, Eveline M. Ibeagha-Awemu, Ali Jawaid, Wei Jiang, Oscar Juez, Ashley M. Karnay, Kentaro Kawata, Hasan Khatib, Eric W. Klee, Kerstin Klein, Eloïse A. Kremer, Ilkka Kronholm, Ho-Sun Lee, Frédérique Magdinier, Isabelle M. Mansuy, Rahia Mashoodh, Mihaly Mezei, Maria Miah, Matin Miryeganeh, Shiraz Mujtaba, Pamela N. Munster, Rabih Murr, Rūta Navakauskienė, Claudia Negrón-Lomas, Fereshteh S. Nugent, Elisa Oltra, Rena Onoguchi-Mizutani, Nail Can Öztürk, Romain Pacaud, Jacob Peedicayil, Prasad Pethe, Gerd P. Pfeifer, Sravani Pulya, Tibor A. Rauch, Marisol Resendiz, Marcus Roalsø, Jérôme D. Robin, Julien Rossignol, Joanne Ryan, Cíntia Barros Santos-Rebouças, Hidetoshi Saze, Ryan D. Shepard, Philippe Silar, Athena Sklias, Susan L. Slager, Kjetil Søreide, Bhairavi Srinageshwar, David M. Suter, Kenzui Taniue, Scott Thomas, Shulan Tian, Trygve O. Tollefsbol, Mark van der Giezen, Ludovica Vanzan, Günter Vogt, Darryl S. Watkins, Martin M. Watson, Loo Keat Wei, Jo Wrigglesworth, Toshimichi Yamada, Huihuang Yan, Jie Yang, Zhengzhou Ying, Ericka Zacarias, Feng C. Zhou
Publikováno v:
Handbook of Epigenetics ISBN: 9780323919098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d4acac4d28fc4a91274d2bedcade435
https://doi.org/10.1016/b978-0-323-91909-8.00047-5
https://doi.org/10.1016/b978-0-323-91909-8.00047-5