Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Courtney T. Stump"'
Autor:
Michael J. Walsh, Courtney T. Stump, Rakeeb Kureshi, Patrick Lenehan, Lestat R. Ali, Michael Dougan, David M. Knipe, Stephanie K. Dougan
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112219- (2023)
Summary: Tumors in immune equilibrium are held in balance between outgrowth and destruction by the immune system. The equilibrium phase defines the duration of clinical remission and stable disease, and escape from equilibrium remains a major clinica
Externí odkaz:
https://doaj.org/article/f1f8592f2d8e4bfab43410d828e98a6f
Publikováno v:
Open Biology, Vol 11, Iss 11 (2021)
Radiation has been a pillar of cancer therapy for decades. The effects of radiation on the anti-tumour immune response are variable across studies and have not been explicitly defined in poorly immunogenic tumour types. Here, we employed combination
Externí odkaz:
https://doaj.org/article/96fb3005c03b4be6bd40acd0d2701cc0
Autor:
Katherine S. Ventre, Kevin Roehle, Elisa Bello, Aladdin M. Bhuiyan, Tamara Biary, Stephanie J. Crowley, Patrick T. Bruck, Max Heckler, Patrick J. Lenehan, Lestat R. Ali, Courtney T. Stump, Victoria Lippert, Eleanor Clancy-Thompson, Winiffer D. Conce Alberto, Megan T. Hoffman, Li Qiang, Marc Pelletier, James J. Akin, Michael Dougan, Stephanie K. Dougan
Publikováno v:
J Immunol
Checkpoint blockade immunotherapy has failed in pancreatic cancer and other poorly responsive tumor types in part due to inadequate T cell priming. Naive T cells can receive costimulation not only via CD28 but also through TNF superfamily receptors t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c92cc354c85c80715fc972a7d9c421
https://europepmc.org/articles/PMC10036868/
https://europepmc.org/articles/PMC10036868/
Autor:
Lestat R. Ali, Ana C. Garrido-Castro, Patrick J. Lenehan, Naima Bollenrucher, Courtney T. Stump, Michael Dougan, Shom Goel, Geoffrey I. Shapiro, Sara M. Tolaney, Stephanie K. Dougan
Publikováno v:
Journal of Experimental Medicine. 220
We performed single-cell RNA-sequencing and T cell receptor clonotype tracking of breast and ovarian cancer patients treated with the CDK4/6 inhibitor ribociclib and PD-1 blockade. We highlight evidence of two orthogonal treatment-associated phenomen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::922584ac8270d8a201bfc7172c380e12
https://doi.org/10.1084/jem.20220729
https://doi.org/10.1084/jem.20220729
Publikováno v:
Open Biology, Vol 11, Iss 11 (2021)
Open Biology
Open Biology
Radiation has been a pillar of cancer therapy for decades. The effects of radiation on the anti-tumour immune response are variable across studies and have not been explicitly defined in poorly immunogenic tumour types. Here, we employed combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e64f6dd93a059114f072f5605bf248
https://doi.org/10.1098/rsob.210245
https://doi.org/10.1098/rsob.210245
Autor:
Max Heckler, Courtney T. Stump, Katherine S. Ventre, Li Qiang, Katelyn T. Byrne, Stephanie K. Dougan, Joseph D. Mancias, Daniel Heid, Lestat R. Ali, Aladdin M. Bhuiyan, Tamara Biary, Annan Yang, Patrick T. Bruck, Svenja L. Nopper, Jana F. Tegethoff, Jinyang Li, Marc Pelletier, Ben Z. Stanger, Kevin Roehle, Anže Godicelj, James J. Akin, Patrick J Lenehan, Michael Dougan, Judith Agudo, Kai W. Wucherpfennig, Maria Quiles Del Rey, Adrienne M. Luoma, Stephanie J. Crowley, Gabrielle Ro
Publikováno v:
Sci Transl Med
Loss of major histocompatibility complex (MHC) class I and interferon (IFN)-γ sensing are major causes of primary and acquired resistance to checkpoint blockade immunotherapy. Thus, additional treatment options are needed for tumors that lose expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53d8b17fad8bce1af5dcb723ab06941
https://europepmc.org/articles/PMC8406785/
https://europepmc.org/articles/PMC8406785/
Autor:
Courtney T Stump, Chenkai Mao, Jennifer Fields, Gregory W. Ho, Veronique Beiss, Frank A. Veliz, Nicole F. Steinmetz, Steven Fiering
Publikováno v:
Cancers
Volume 13
Issue 4
Cancers, Vol 13, Iss 627, p 627 (2021)
Volume 13
Issue 4
Cancers, Vol 13, Iss 627, p 627 (2021)
Simple Summary Ovarian cancer survival rates are poor, with most deaths occurring from cancer recurrence following initial remission. Accordingly, there is a significant need for treatments that prevent relapse. Here, using a therapeutic vaccine agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432f2a2ac467cec42d6cf19f108294b7
http://europepmc.org/articles/PMC7915664
http://europepmc.org/articles/PMC7915664
Publikováno v:
Vaccine Weekly; 3/22/2024, p432-432, 1p
Remission-Stage Ovarian Cancer Cell Vaccine with Cowpea Mosaic Virus Adjuvant Prevents Tumor Growth.
Autor:
Stump, Courtney T.1 (AUTHOR) courtney.t.stump.20@dartmouth.edu, Ho, Gregory2 (AUTHOR) gregory.w.ho.gr@dartmouth.edu, Mao, Chenkai2 (AUTHOR) chenkai.mao.gr@dartmouth.edu, Veliz, Frank A.3 (AUTHOR) frank.veliz@case.edu, Beiss, Veronique4 (AUTHOR) vbeiss@ucsd.edu, Fields, Jennifer5 (AUTHOR) jennifer.l.fields@dartmouth.edu, Steinmetz, Nicole F.4,6,7,8,9,10 (AUTHOR) nsteinmetz@ucsd.edu, Fiering, Steven2,5 (AUTHOR) fiering@dartmouth.edu, Ksiązek, Krzysztof (AUTHOR), Lopez-Cabrera, Manuel (AUTHOR)
Publikováno v:
Cancers. 2/15/2021, Vol. 13 Issue 4, p627-627. 1p.