Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Courtney R Little"'
Autor:
Omar Niss, Monika Asnani, Alisa Dong, Punam Malik, Archana Shrestha, Carolyn Lutzko, Charles T. Quinn, Paritha Arumugam, Sydney Felker, Courtney R Little, Scott Witting, Chris Lo, Jennifer Knight-Madden, Michael Grimley
Publikováno v:
Blood. 138:3970-3970
Introduction: Sickle cell disease (SCD) is a genetic red blood cell (RBC) disorder that causes chronic hemolytic anemia, progressive organ damage, and life-threatening acute complications such as painful vaso-occlusive crises. Allogeneic hematopoieti
Autor:
Charles T. Quinn, Monika Asnani, Punam Malik, Archana Shrestha, Chris Lo, Omar Niss, Joseph W. McIntosh, Paritha Arumugam, Carolyn Lutzko, Courtney R Little, Scott Witting, Jennifer Knight-Madden, Michael Grimley, Sydney Felker
Publikováno v:
Blood. 136:20-21
Introduction: ARU-1801 is a gene therapy consisting of autologous CD34+ hematopoietic stem cells and progenitors (HSCPs) transduced with a lentiviral vector (LV) encoding a modified γ-globinG16D gene. Preclinical studies in SCD mice have shown that
Autor:
Susan E. Stuber, Margaret Wisdom-Phipps, Angela Rankine-Mullings, Deanne Soares, Karen Aldred, Marvin Reid, Teresa Latham, Russell E. Ware, Jennifer Knight-Madden, Carolyn Taylor-Bryan, Courtney R Little, Asha Badaloo
Publikováno v:
JMIR Research Protocols
Background: Cerebral vasculopathy in sickle cell anemia (SCA) begins in childhood and features intracranial arterial stenosis with high risk of ischemic stroke. Stroke risk can be reduced by transcranial doppler (TCD) screening and chronic transfusio