Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Courtney M. Simpson"'
Autor:
Courtney M. Simpson, Robert B. Gilchrist, Kenneth P. McNatty, David G. Mottershead, Peter G. Stanton, Craig A. Harrison, David Robertson, D. A. Heath, Sara L. Al-Musawi, Lesley J. Ritter
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E615-E624
Growth differentiation factor 9 (GDF9) is a central regulator of folliculogenesis and ovulation rate. Fourteen mutations in human (h) GDF9 have been reported in women with premature ovarian failure or polycystic ovarian syndrome as well as in mothers
Autor:
Karen L. Chan, Robert B. Gilchrist, Peter G. Stanton, Craig A. Harrison, Kelly L. Walton, Courtney M. Simpson, Lesley J. Ritter
Publikováno v:
Endocrinology. 153:1301-1310
Growth differentiation factor 9 (GDF9) controls granulosa cell growth and differentiation during early ovarian folliculogenesis and regulates cumulus cell function and ovulation rate in the later stages of this process. Similar to other TGF-β superf
Publikováno v:
Endocrinology. 154(2)
Oocyte-derived bone morphogenetic protein 15 (BMP15) regulates ovulation rate and female fertility in a species-specific manner, being important in humans and sheep and largely superfluous in mice. To understand these species differences, we have com
Publikováno v:
Biology of Reproduction. 87:503-503
Publikováno v:
Reproduction, Fertility and Development. 22:46
Premature Ovarian Failure (POF) is a disorder associated with female infertility affecting 1% of women under the age of 40 years [1]. It is characterised by amenorrhea associated with an increase in plasma gonadotrophins and decreased estrogen [2, 3]