Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Courtney M. Shea"'
Autor:
Chad D. Schwartzkopf, John R. Hadcock, Guang Liu, Peter Germano, Julien Roux, Courtney M. Shea, Emmanuel S. Buys, Juli E. Jones
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Praliciguat is a soluble guanylate cyclase stimulator that elicits hemodynamic, anti-inflammatory, and antifibrotic effects in preclinical models of metabolic dysfunction. We assessed the metabolic effects of praliciguat in a mouse diet-induced obesi
Externí odkaz:
https://doaj.org/article/276425e92d2143c0a1202416a49b9492
Autor:
Daniel P. Zimmer, Courtney M. Shea, Jenny V. Tobin, Boris Tchernychev, Peter Germano, Kristie Sykes, Ali R. Banijamali, Sarah Jacobson, Sylvie G. Bernier, Renee Sarno, Andrew Carvalho, Yueh-tyng Chien, Regina Graul, Emmanuel S. Buys, Juli E. Jones, James D. Wakefield, Gavrielle M. Price, Jennifer G. Chickering, G. Todd Milne, Mark G. Currie, Jaime L. Masferrer
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic 3',5' GMP (cGMP) signaling plays a central role in regulation of diverse processes including smooth muscle relaxation, inflammation, and fibrosis. sGC is activated by the short-lived physiologi
Externí odkaz:
https://doaj.org/article/e994be112c3a40db87031271143e9556
Autor:
Virginia Reverte, Francisca Rodriguez, Lidia Oltra, Juan M. Moreno, María T. Llinás, Courtney M. Shea, Chad D. Schwartzkopf, Emmanuel S. Buys, Jaime L. Masferrer, F. Javier Salazar
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 322(4)
Prolonged high-fat diet (HFD) accelerates the cardiovascular, renal, and metabolic dysfunction in hypertensive rats with altered renal development (ARDev). Soluble guanylate cyclase (sGC) stimulation or sodium-glucose cotransporter 2 (SGLT2) inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9e6c05a827e83b5dbbf0be9c52a88a
https://pubmed.ncbi.nlm.nih.gov/35119333
https://pubmed.ncbi.nlm.nih.gov/35119333