Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Courtney M. Fernandez-Petty"'
Autor:
Qian Li, Kadambari Vijaykumar, Scott E. Phillips, Shah S. Hussain, Nha V. Huynh, Courtney M. Fernandez-Petty, Jacelyn E. Peabody Lever, Jeremy B. Foote, Janna Ren, Javier Campos-Gómez, Farah Abou Daya, Nathaniel W. Hubbs, Harrison Kim, Ezinwanne Onuoha, Evan R. Boitet, Lianwu Fu, Hui Min Leung, Linhui Yu, Thomas W. Detchemendy, Levi T. Schaefers, Jennifer L. Tipper, Lloyd J. Edwards, Sixto M. Leal Jr., Kevin S. Harrod, Guillermo J. Tearney, Steven M. Rowe
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
Substantial clinical evidence supports the notion that ciliary function in the airways is important in COVID-19 pathogenesis. Although ciliary damage has been observed in both in vitro and in vivo models, the extent or nature of impairment of mucocil
Externí odkaz:
https://doaj.org/article/0c708e5e467241419dc7f4ebe99420b0
Autor:
Johnathan D. Keith, Alexander G. Henderson, Courtney M. Fernandez-Petty, Joy M. Davis, Ashley M. Oden, Susan E. Birket
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cystic fibrosis (CF) airway disease is characterized by excessive and accumulative mucus in the airways. Mucociliary clearance becomes defective as mucus secretions become hyperconcentrated and viscosity increases. The CFTR-knockout (KO) rat has been
Externí odkaz:
https://doaj.org/article/d0506cadbe8a463e9c94940acdad5073
Autor:
Eric J. Sorscher, Guillermo J. Tearney, Gojun Zhao, Lianwu Fu, Susan E. Birket, Alexander G Henderson, Ashley M Oden, Joy M. Davis, Liping Tang, Andre Chambers, Alvin Fields, Jeong S. Hong, Courtney M. Fernandez-Petty, Steven M. Rowe, Hui Wen
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: Animal models have been highly informative for understanding the characteristics, onset, and progression of cystic fibrosis (CF) lung disease. In particular, the CFTR−/− rat has revealed...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d07fd5ed9e008f8d9caf14811510596
https://pubmed.ncbi.nlm.nih.gov/32692578
https://pubmed.ncbi.nlm.nih.gov/32692578
Autor:
Hui Zheng, Susan E. Birket, Tim N. Ford, Bryan P. Hurley, Justin H. Palermo, Lael M. Yonker, Ren-Jay Shei, Chulho Hyun, Do-Yeon Cho, George M. Solomon, Adegboyega Timothy Adewale, Guillermo J. Tearney, Hui Min Leung, Courtney M. Fernandez-Petty, Dongyao Cui, Bradford A. Woodworth, A. Lenzie, Steven M. Rowe
Publikováno v:
Science Translational Medicine. 11
Cystic fibrosis (CF) is a genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Although impairment of mucociliary clearance contributes to severe morbidity and mortality in people with CF, a clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91cb13c2ffd10134d74e9f52771a279
https://doi.org/10.1126/scitranslmed.aav3505
https://doi.org/10.1126/scitranslmed.aav3505
Autor:
Susan E. Birket, Stacy M. Townsend, Kengyeh K. Chu, Guillermo J. Tearney, William P. Wiesmann, Steven M. Rowe, Justin Hanes, John F. Engelhardt, Gareth W. Hughes, T. Idil Apak Evans, Bradley H. Rosen, John P. Clancy, Heather Hathorne, John D. Watson, David J. Thornton, Hannah L. Bowers, Bryan Garcia, Carlo Santos, Courtney M. Fernandez-Petty, Shenda M. Baker, Hui Min Leung, William E. Swords, Emily Falk Libby, Caroline Ridley, Marina Mazur, Yao Li
Cystic fibrosis (CF) is characterized by increased mucus viscosity and delayed mucociliary clearance that contributes to progressive decline of lung function. Mucus in the respiratory and GI tract is excessively adhesive in the presence of airway deh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d5e900083854397764665a54285305
https://europepmc.org/articles/PMC6538343/
https://europepmc.org/articles/PMC6538343/
