Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Courtney M Starks"'
Autor:
Matthew B Kilgore, Megan M Augustin, Courtney M Starks, Mark O'Neil-Johnson, Gregory D May, John A Crow, Toni M Kutchan
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103223 (2014)
Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer's disease. This compound is primarily isolated from daffodil (Narcissus spp.), snowdrop (Galanthus spp.), and summer snowflake (Leucojum aestivum). Despite its importa
Externí odkaz:
https://doaj.org/article/5c7da27cb86049a3b775279f7571edce
Autor:
Gary R. Eldridge, Heidi Hughey, Lois Rosenberger, Steven M. Martin, Andrew Marc Shapiro, Elizabeth D’Antonio, Kent G. Krejci, Neal Shore, James Peterson, Andrea S. Lukes, Courtney M. Starks
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 5, Pp 1262-1270 (2021)
Antibiotic resistance among gram-negative bacteria continues to rise globally at an alarming rate. New vaccines that prevent bacterial infections and reduce antibiotic use could provide a potential solution to these problems. This study focused on de
Externí odkaz:
https://doaj.org/article/97940187c7234a63a0394e6d90da40b3
Autor:
Courtney M. Starks, Michelle M. Miller, Peter M. Broglie, Joshua Cubbison, Steven M. Martin, Gary R. Eldridge
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 1, Pp 283-292 (2021)
Recurrent urinary tract infections (rUTI) are a serious disease associated with morbidities and mortality. Resistance to the standard of care antibiotics is now widespread because of the continued use of antibiotics among people who suffer from rUTI.
Externí odkaz:
https://doaj.org/article/c15ede1b79074204abc5cb76d24ad229
Autor:
Gary R. Eldridge, Andrew Marc Shapiro, Lois Rosenberger, James Peterson, Neal Shore, Steven M. Martin, Andrea S. Lukes, Kent G. Krejci, Heidi Hughey, Elizabeth D’Antonio, Courtney M. Starks
Publikováno v:
Human Vaccines & Immunotherapeutics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Antibiotic resistance among gram-negative bacteria continues to rise globally at an alarming rate. New vaccines that prevent bacterial infections and reduce antibiotic use could provide a potential solution to these problems. This study focused on de
Autor:
Gary R. Eldridge, Steven M. Martin, Michelle M Miller, Courtney M. Starks, Joshua Cubbison, Peter M Broglie
Publikováno v:
Human Vaccines & Immunotherapeutics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Recurrent urinary tract infections (rUTI) are a serious disease associated with morbidities and mortality. Resistance to the standard of care antibiotics is now widespread because of the continued use of antibiotics among people who suffer from rUTI.
Autor:
Anna R. Ilivicky, Lei Guo, Carolyn K. McCourt, Premal H. Thaker, K.A. Mills, Elena Lomonosova, Julie A. Lawrence, Katherine Fuh, Andrea R. Hagemann, J.M. Quinn, Matthew A. Powell, Courtney M. Starks, Hollie M. Beck, David G. Mutch, S. Tanner Roach
Publikováno v:
Gynecologic Oncology. 151:337-344
Objective Paclitaxel, a microtubule inhibitor, is subject to tumor resistance while treating high-grade serous ovarian and uterine cancer. This study aims to directly compare the effects of SQ1274, a novel microtubule inhibitor that binds to the colc
Autor:
Zhongping Huang, Gary R. Eldridge, Russell B. Williams, Mark O’Neil-Johnson, John E. Mangette, Courtney M. Starks
Publikováno v:
The Journal of Organic Chemistry. 82:4235-4241
The first total synthesis of bifidenone, a novel natural tubulin polymerization inhibitor, has been achieved in 12 steps starting from commercially available 1,4-dioxaspiro[4.5]decan-8-one. The synthesis includes a newly developed method to generate
Autor:
Ashutosh K. Shukla, Linna Han, Megan M. Augustin, Toni M. Kutchan, Cynthia K. Holland, Courtney M. Starks, Mark O’Neil-Johnson
Publikováno v:
Plant Biotechnology Reports. 11:29-41
Economically feasible systems for heterologous production of complex secondary metabolites originating from difficult to cultivate species are in demand since Escherichia coli and Saccharomyces cerevisiae are not always suitable for expression of pla
Autor:
Sivaprakash Rathinavelu, Jin-Feng Hu, Michael Ellis, Gary R. Eldridge, Russell B. Williams, Vanessa L. Norman, Julie A. Lawrence, Eliane Garo, Zhongping Huang, Courtney M. Starks, Ronald N. Buckle
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115229
Many human diseases, including cystic fibrosis lung infections, are caused or exacerbated by bacterial biofilms. Specialized modes of motility, including swarming and twitching, allow gram-negative bacteria to spread across surfaces and form biofilms
Autor:
Gary R. Eldridge, Peter R. Guzzo, James P. Harding, Mark O’Neil-Johnson, John E. Mangette, Courtney M. Starks, Shuang Liu, Steven M. Martin, Julie A. Lawrence, Zhongping Huang, Russell B. Williams, Vanessa L. Norman
Publikováno v:
Journal of medicinal chemistry. 61(15)
Bifidenone is a novel natural tubulin polymerization inhibitor that exhibits antiproliferative activity against a range of human cancer cell lines, making it an attractive candidate for development. A synthetic route was previously developed to allev