Differential contribution of CBP:CREB binding to corticotropin-releasing hormone expression in the infant and adult hypothalamus

Autor: George A. Rogge, Marcelo A. Wood, Limor Regev, Tallie Z. Baram, Jessica Lack Cope, Sung Ji, Aniko Korosi, Courtney J. Rice, Yuncai Chen

Publikováno v: Stress-the International Journal on the Biology of Stress, 17(1), 39-50. Informa Healthcare

Corticotropin-releasing hormone (CRH) contributes crucially to the regulation of central and peripheral responses to stress. Because of the importance of a finely-tuned stress system, CRH expression is tightly regulated in an organ- and brain region-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531e5621775dd4d210707a6ae5e0f21a
https://doi.org/10.3109/10253890.2013.806907

Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress

Autor: Yuncai Chen, Pamela M. Maras, Jenny Molet, Ana Solodkin, Tallie Z. Baram, Sunggoan Ji, Courtney J. Rice

Publikováno v: Maras, PM; Molet, J; Chen, Y; Rice, C; Ji, SG; Solodkin, A; et al.(2014). Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress. Molecular Psychiatry. doi: 10.1038/mp.2014.12. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6bg9k842
Molecular Psychiatry

The cognitive effects of stress are profound, yet it is unknown if the consequences of concurrent multiple stresses on learning and memory differ from those of a single stress of equal intensity and duration. We compared the effects on hippocampus-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f02108d96d991390a8d9f80a192eac
http://www.escholarship.org/uc/item/6bg9k842

Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits

Autor: Xiao-Dong, Wang, Gerhard, Rammes, Igor, Kraev, Miriam, Wolf, Claudia, Liebl, Sebastian H, Scharf, Courtney J, Rice, Wolfgang, Wurst, Florian, Holsboer, Jan M, Deussing, Tallie Z, Baram, Michael G, Stewart, Marianne B, Müller, Mathias V, Schmidt

Publikováno v: The journal of neuroscience 31(38), 13625-13634 (2011). doi:10.1523/JNEUROSCI.2259-11.2011

Childhood traumatic events hamper the development of the hippocampus and impair declarative memory in susceptible individuals. Persistent elevations of hippocampal corticotropin-releasing factor (CRF), acting through CRF receptor 1 (CRF1), in experim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b1f046e61abce6b7a81d8611683aa1a5

A novel mouse model for acute and long-lasting consequences of early life stress

Autor: Tallie Z. Baram, Curt A. Sandman, Mohammed R. Lenjavi, Courtney J. Rice

Publikováno v: Rice, Courtney J; Sandman, Curt A; Lenjavi, Mohammed R; & Baram, Tallie Z. (2008). A novel mouse model for acute and long-lasting consequences of early life stress.. Endocrinology, 149(10), 4892-4900. doi: 10.1210/en.2008-0633. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5fb1v1zn

Chronic early-life stress (ES) exerts profound acute and long-lasting effects on the hypothalamic-pituitary-adrenal system, with relevance to cognitive function and affective disorders. Our ability to determine the molecular mechanisms underlying the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e158f2530aab360ed5f1b4f9f163a23a
https://pubmed.ncbi.nlm.nih.gov/18566122