Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Courtney E. McDougal"'
Autor:
Grischa Y. Chen, Courtney E. McDougal, Marc A. D’Antonio, Jonathan L. Portman, John-Demian Sauer
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Through unknown mechanisms, the host cytosol restricts bacterial colonization; therefore, only professional cytosolic pathogens are adapted to colonize this host environment. Listeria monocytogenes is a Gram-positive intracellular pathogen t
Externí odkaz:
https://doaj.org/article/ed0bcc16973e409c9cbab7bfa70aeca2
Publikováno v:
Pathogens, Vol 7, Iss 1, p 8 (2018)
Listeria monocytogenes has evolved exquisite mechanisms for invading host cells and spreading from cell-to-cell to ensure maintenance of its intracellular lifecycle. As such, it is not surprising that loss of the intracellular replication niche throu
Externí odkaz:
https://doaj.org/article/4b15ef59bd8040bf95f517cd70a3e805
Autor:
Veronika Miskolci, Kelsey E Tweed, Michael R Lasarev, Emily C Britt, Alex J Walsh, Landon J Zimmerman, Courtney E McDougal, Mark R Cronan, Jing Fan, John-Demian Sauer, Melissa C Skala, Anna Huttenlocher
Publikováno v:
eLife
The function of macrophages in vitro is linked to their metabolic rewiring. However, macrophage metabolism remains poorly characterized in situ. Here, we used two-photon intensity and lifetime imaging of autofluorescent metabolic coenzymes, nicotinam
Autor:
Veronika Miskolci, Kelsey E Tweed, Michael R Lasarev, Emily C Britt, Alex J Walsh, Landon J Zimmerman, Courtney E McDougal, Mark R Cronan, Jing Fan, John-Demian Sauer, Melissa C Skala, Anna Huttenlocher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9900dee3c296a6adb3dc89b102b87e89
https://doi.org/10.7554/elife.66080.sa2
https://doi.org/10.7554/elife.66080.sa2
Autor:
Seonyoung Kim, Tighe Christopher, Zachary Morrow, Courtney E. McDougal, David M. Stevenson, Drake Carter, Mark J. Miller, Daniel Amador-Noguez, John-Demian Sauer
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009493 (2021)
PLoS Pathogens
PLoS Pathogens
Listeria monocytogenes is an intracellular bacterium that elicits robust CD8+ T-cell responses. Despite the ongoing development of L. monocytogenes-based platforms as cancer vaccines, our understanding of how L. monocytogenes drives robust CD8+ T-cel
Autor:
Seung Il Kim, Zachary Morrow, David M. Stevenson, Carter D, Mark J. Miller, Daniel Amador-Noguez, John-Demian Sauer, Courtney E. McDougal
Listeria monocytogenes is an intracellular bacterium that elicits robust CD8+ T-cell responses. Despite the ongoing development of L. monocytogenes-based platforms as cancer vaccines, our understanding of how L. monocytogenes drives robust CD8+ T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de8b7e82057d1f4a94935cf6f373ca52
https://doi.org/10.1101/2021.03.23.436585
https://doi.org/10.1101/2021.03.23.436585
Autor:
Nikhila S Bharadwaj, Nicholas J Hess, Shidong Ma, Jenny E. Gumperz, Elizabeth A Bobeck, Courtney E. McDougal, John-Demian Sauer, Amy W. Hudson
Publikováno v:
Life Science Alliance
Immunotherapeutic iNKT cells interact with monocytes and T cells in human umbilical cord blood grafts to simultaneously limit inflammation while promoting hematopoietic activity.
Invariant natural killer T (iNKT) cells are a conserved population
Invariant natural killer T (iNKT) cells are a conserved population
Autor:
Courtney E. McDougal, Jing Fan, Veronika Miskolci, Emily C. Britt, John-Demian Sauer, Anna Huttenlocher, Kelsey Tweed, Melissa C. Skala, Michael R. Lasarev, Alex J. Walsh
The effector functions of macrophages across the spectrum of activation statesin vitroare linked to profound metabolic rewiring. However, the metabolism of macrophages remains poorly characterizedin vivo. To assess changes in the intracellular metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bafc71585b62306b02b7e6667cd9e52
https://doi.org/10.1101/2020.06.16.153361
https://doi.org/10.1101/2020.06.16.153361
Autor:
Daniel W. Rosenberg, Courtney E. McDougal, Laura J. Knoll, David M. Stevenson, Erin Theisen, Daniel Amador-Noguez, Masako Nakanishi, John-Demian Sauer
Publikováno v:
The Journal of Immunology. 200:3729-3738
Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase (COX) activity and are commonly used for pain relief and fever reduction. NSAIDs are used following childhood vaccinations and cancer immunotherapies; however, how NSAIDs influence
Publikováno v:
The Journal of Immunology. 204:169.3-169.3
The bacterial pathogen Listeria monocytogenes (Lm) is being developed as a cancer immunotherapeutic platform due to its ability to elicit robust CD8+ T cell responses. Though the role of cytokines in Lm-stimulated immunity is well studied, the role o