Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Courtney Culpepper"'
Autor:
William Becker, Haider Rasheed Alrafas, Kiesha Wilson, Kathryn Miranda, Courtney Culpepper, Ioulia Chatzistamou, Guoshuai Cai, Mitzi Nagarkatti, Prakash S. Nagarkatti
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101504- (2020)
Summary: Intestinal disequilibrium leads to inflammatory bowel disease (IBD), and chronic inflammation predisposes to oncogenesis. Antigen-presenting dendritic cells (DCs) and macrophages can tip the equilibrium toward tolerance or pathology. Here we
Externí odkaz:
https://doaj.org/article/affab4cf134848f79316cc248de1a0f2
Autor:
Mitzi Nagarkatti, Kathryn Miranda, Prakash S. Nagarkatti, Ioulia Chatzistamou, William Becker, Haider Rasheed Alrafas, Guoshuai Cai, Kiesha Wilson, Courtney Culpepper
Publikováno v:
iScience
iScience, Vol 23, Iss 9, Pp 101504-(2020)
iScience, Vol 23, Iss 9, Pp 101504-(2020)
Summary Intestinal disequilibrium leads to inflammatory bowel disease (IBD), and chronic inflammation predisposes to oncogenesis. Antigen-presenting dendritic cells (DCs) and macrophages can tip the equilibrium toward tolerance or pathology. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27456dc5448b48eaa6bde6bf3c0f2985
http://europepmc.org/articles/PMC7501437
http://europepmc.org/articles/PMC7501437
Autor:
Mahathi Venkataramani, Ahmed Mansour Abdelaal, Zhen Bian, Lei Shi, Yuan Liu, Courtney Culpepper, Hongwei Liang, Koby Kidder, Ke Zen
Publikováno v:
European Journal of Immunology. 48:532-542
Myeloid-derived suppressor cells (MDSCs) promote tumor growth through, in part, inhibiting T-cell immunity. However, mechanisms underlying MDSC expansion and guidance of MDSCs toward the tumor microenvironment remain unclear. Employing Percoll densit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72240dbded775119f9e624de6d2216fb
https://doi.org/10.1002/eji.201746976
https://doi.org/10.1002/eji.201746976
Publikováno v:
The Journal of Immunology. 204:63.9-63.9
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid that has anti-inflammatory properties; however the precise immunological mechanisms involved are not clear. Research from our laboratory has established that CBD promotes expansion of immunosup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9abae9266ae6d17461a97ee236d75ce
https://doi.org/10.4049/jimmunol.204.supp.63.9
https://doi.org/10.4049/jimmunol.204.supp.63.9
Autor:
Koby Kidder, Lanqiao Xiong, Ahmed Mansour Abdelaal, Hongwei Liang, Mahathi Venkataramani, Yuan Liu, Ke Zen, Courtney Culpepper, Zhen Bian, Lei Shi
Although previous reports suggest that tumor-induced myeloid-derived suppressor cells (MDSC) inhibit T cells by L-arginine depletion through arginase-1 activity, we herein show that arginase-1 is neither inherently expressed in MDSC nor required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26026ec18211f6e252d76d6bf7419ca3
https://europepmc.org/articles/PMC5997508/
https://europepmc.org/articles/PMC5997508/
Autor:
Ke Zen, Yongliang Zhang, Limin Li, Courtney Culpepper, Ya-Lan Guo, Koby Kidder, Zhen Bian, Zhiyuan Lv, Yuan Liu, Lei Shi, Cong Tang, Alexandra Tremblay, Shuo Niu, Zhen Zhou, Mahathi Venkataramani, Andrew T. Gewirtz, Ahmed Mansour
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(37)
Rapid clearance of adoptively transferred Cd47-null (Cd47(-/-)) cells in congeneic WT mice suggests a critical self-recognition mechanism, in which CD47 is the ubiquitous marker of self, and its interaction with macrophage signal regulatory protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac46da3343395b4f96a21b42d6430460
https://pubmed.ncbi.nlm.nih.gov/27578867
https://pubmed.ncbi.nlm.nih.gov/27578867
Publikováno v:
The Journal of Immunology. 198:154.13-154.13
Tumor-induced myeloid derived suppressive cells (MDSC) have been reported to inhibit T cell responses. In our study MDSC inhibit T cell proliferation through arginase-1 dependent manner. However, surprisingly we observe that freshly isolated MDSC fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02b62dec884f35eb783f93679ece001
https://doi.org/10.4049/jimmunol.198.supp.154.13
https://doi.org/10.4049/jimmunol.198.supp.154.13
Publikováno v:
The Journal of Immunology. 196:188.15-188.15
Myeloid-derived suppressor cells (MDSC) emerging during tumor growth or chronic inflammation play a critical role in regulating T cell function. However, mechanisms governing the generation of these cells remain unclear and need to be further defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e44242cca96556a021ae31702e6b2a8
https://doi.org/10.4049/jimmunol.196.supp.188.15
https://doi.org/10.4049/jimmunol.196.supp.188.15