Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Courtney A. Copeland"'
Autor:
Ryan Connor, Migun Shakya, David A. Yarmosh, Wolfgang Maier, Ross Martin, Rebecca Bradford, J. Rodney Brister, Patrick S. G. Chain, Courtney A. Copeland, Julia di Iulio, Bin Hu, Philip Ebert, Jonathan Gunti, Yumi Jin, Kenneth S. Katz, Andrey Kochergin, Tré LaRosa, Jiani Li, Po-E Li, Chien-Chi Lo, Sujatha Rashid, Evguenia S. Maiorova, Chunlin Xiao, Vadim Zalunin, Lisa Purcell, Kim D. Pruitt
Publikováno v:
Viruses, Vol 16, Iss 3, p 430 (2024)
Genomic sequencing of clinical samples to identify emerging variants of SARS-CoV-2 has been a key public health tool for curbing the spread of the virus. As a result, an unprecedented number of SARS-CoV-2 genomes were sequenced during the COVID-19 pa
Externí odkaz:
https://doaj.org/article/6e7497a5dbab4a889e0bcc3256afa440
Effects of COVID-19 Sport Suspension on Injury Rates in Elite Athletes: A Critically Appraised Topic
Publikováno v:
International Journal of Athletic Therapy and Training. :1-5
Clinical Scenario: With the enforcement of COVID-19 lockdown restrictions, sports teams worldwide were required to make drastic adjustments to their training regimen. This prolonged sport suspension resulted in a significant decrease in off-season an
Autor:
Ryan Connor, David A. Yarmosh, Wolfgang Maier, Migun Shakya, Ross Martin, Rebecca Bradford, J. Rodney Brister, Patrick SG Chain, Courtney A. Copeland, Julia di Iulio, Bin Hu, Philip Ebert, Jonathan Gunti, Yumi Jin, Kenneth S. Katz, Andrey Kochergin, Tré LaRosa, Jiani Li, Po-E Li, Chien-Chi Lo, Sujatha Rashid, Evguenia S. Maiorova, Chunlin Xiao, Vadim Zalunin, Kim D. Pruitt
Publikováno v:
bioRxiv
During the COVID-19 pandemic, SARS-CoV-2 surveillance efforts integrated genome sequencing of clinical samples to identify emergent viral variants and to support rapid experimental examination of genome-informed vaccine and therapeutic designs. Given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6550d09025416ae5944daa3d0cdbd47c
https://europepmc.org/articles/PMC9645426/
https://europepmc.org/articles/PMC9645426/
Autor:
Joshua D Doyle, Jennifer E Stencel-Baerenwald, Courtney A Copeland, Jillian P Rhoads, Judy J Brown, Kelli L Boyd, James B Atkinson, Terence S Dermody
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004693 (2015)
Reovirus is a nonenveloped mammalian virus that provides a useful model system for studies of viral infections in the young. Following internalization into host cells, the outermost capsid of reovirus virions is removed by endosomal cathepsin proteas
Externí odkaz:
https://doaj.org/article/9596dbeddd43435b85566c34ebe647f0
Autor:
Katherine J Nicholas, Emily K Zern, Louise Barnett, Rita M Smith, Shelly L Lorey, Courtney A Copeland, Shanmugalakshmi Sadagopal, Spyros A Kalams
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84185 (2013)
Infection with Human Immunodeficiency Virus Type 1 (HIV-1) induces defects of both cellular and humoral immune responses. Impaired CD4+ T cell help and B cell dysfunction may partially explain the low frequency of broadly neutralizing antibodies in H
Externí odkaz:
https://doaj.org/article/8308db3806fd47b99dc43288097d4576
Autor:
Courtney A. Copeland, Benjamin A. Olenchock, David R. Ziehr, Sarah McGarrity, Kevin Leahy, Jamey D. Young, Joseph Loscalzo, William M. Oldham
Hypoxia requires metabolic adaptations to sustain energetically demanding cellular activities. While the metabolic consequences of hypoxia have been studied extensively in cancer cell models, comparatively little is known about the metabolic response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3199d716a473802a11b532ec6481ffca
https://doi.org/10.1101/2020.09.21.306464
https://doi.org/10.1101/2020.09.21.306464
Autor:
James West, Anna R. Hemnes, Anne K. Kenworthy, Amber Crabtree, Eric D. Austin, Christy Moore, Anandharajan Rathinasabapathy, James E. Loyd, Courtney A. Copeland, Sheila Shay, Erica J. Carrier, Santhi Gladson
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: In 2012, mutations in Cav1 were found to be the driving mutation in several cases of heritable pulmonary arterial hypertension (PAH). These mutations replaced the last 21 amino acids of Cav1 with a novel 22-amino-acid sequence. Because pr
Autor:
James E. Loyd, Anne K. Kenworthy, Courtney A. Copeland, Ajit Tiwari, Eric D. Austin, Bing Han, James West
Publikováno v:
Molecular Biology of the Cell
Heterozygous mutations in caveolin-1 (CAV1) have been linked to pulmonary arterial hypertension (PAH), but their impact on caveolae is unclear. We show that a PAH-associated frameshift mutation introduces an endoplasmic reticulum retention signal in
Autor:
Mindy Miller-Kittrell, Courtney A. Copeland, Joseph W. Jackson, Tim E. Sparer, Elisabeth A. Pitt, Thomas Masi, Shu-En Wu, Pranay Dogra, William E. Miller
Publikováno v:
Journal of General Virology. 97:2957-2972
Cytomegaloviruses (CMVs) produce chemokines (vCXCLs) that have both sequence and functional homology to host chemokines. Assessment of vCXCL-1's role in CMV infection is limited to in vitro and in silico analysis due to CMVs species specificity. In t
Autor:
Bing Han, Krishnan Raghunathan, Yumeko Kawano, Wendy K. Chung, Courtney A. Copeland, Sha Tang, Layla Shahmirzadi, Anne K. Kenworthy, Eric D. Austin, Erika B. Rosenzweig
Publikováno v:
Traffic. 17:1297-1312
Congenital generalized lipodystrophy (CGL) and pulmonary arterial hypertension (PAH) have recently been associated with mutations in the caveolin-1 ( CAV1 ) gene, which encodes the primary structural protein of caveolae. However, little is currently