Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Courtney A. Becker"'
Autor:
Marissa J Paterson, J R Caldera, Christopher Nguyen, Purnima Sharma, Anthony M Castro, Stacey L Kolar, Chih-Ming Tsai, Jose J Limon, Courtney A Becker, Gislâine A Martins, George Y Liu, David M Underhill
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008733 (2020)
Staphylococcus aureus (S. aureus) is one of the most common bacterial infections worldwide, and antibiotic resistant strains such as Methicillin-Resistant S. aureus (MRSA) are a major threat and burden to public health. MRSA not only infects immunoco
Externí odkaz:
https://doaj.org/article/3606dd28ba864d3ebf84299495851df5
Autor:
Jose J. Limon, J.R. Caldera, Christopher Nguyen, Marissa J Paterson, Chih-Ming Tsai, Stacey L. Kolar, Courtney A. Becker, George Y. Liu, David M. Underhill, Purnima Sharma, Anthony M Castro, Gislâine A. Martins
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008733 (2020)
PLoS Pathogens
PLoS Pathogens
Staphylococcus aureus (S. aureus) is one of the most common bacterial infections worldwide, and antibiotic resistant strains such as Methicillin-Resistant S. aureus (MRSA) are a major threat and burden to public health. MRSA not only infects immunoco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb0a37c7ad32de1144958d76eac87c2
https://doaj.org/article/3606dd28ba864d3ebf84299495851df5
https://doaj.org/article/3606dd28ba864d3ebf84299495851df5
Autor:
Amber Kaplan, Ernest Y. Lee, Michelle W. Lee, Ramachandran Murali, Jose J. Limon, Gerard C. L. Wong, Minna Ding, Andrea J. Wolf, Courtney A. Becker, George Y. Liu, David M. Underhill
Publikováno v:
The Journal of Immunology. 198:4036-4045
Type I IFNs are a cytokine family essential for antiviral defense. More recently, type I IFNs were shown to be important during bacterial infections. In this article, we show that, in addition to known cytokine functions, IFN-β is antimicrobial. Par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b5ba9c8108c07ef8e077f45fff4406
https://doi.org/10.4049/jimmunol.1601226
https://doi.org/10.4049/jimmunol.1601226
Autor:
David M. Underhill, Moshe Arditi, Hee Cheol Cho, Kenichi Shimada, Andrea J. Wolf, K. Mark Coggeshall, Courtney A. Becker, Narcis I. Popescu, Matthew L. Wheeler, Wenbin Liang, Christopher N. Reyes
Publikováno v:
Cell, vol 166, iss 3
Degradation of Gram-positive bacterial cell wall peptidoglycan in macrophage and dendritic cell phagosomes leads to activation of the NLRP3 inflammasome, a cytosolic complex that regulates processing and secretion of interleukin (IL)-1β and IL-18. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3d345c32f891d2f36552a34f3f36eb
https://escholarship.org/uc/item/9jq258m6
https://escholarship.org/uc/item/9jq258m6
Publikováno v:
The Journal of biological chemistry, vol 287, iss 41
Dectin-1 is a pattern recognition receptor that is important for innate immune responses against fungi in humans and mice. Dectin-1 binds to β-glucans in fungal cell walls and triggers phagocytosis, production of reactive oxygen by the NADPH oxidase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ba7e92451b83e29cde730b79fb3c92
https://doi.org/10.1074/jbc.m112.382812
https://doi.org/10.1074/jbc.m112.382812
Autor:
Marla Dubinsky, David M. Underhill, Courtney A. Becker, Vincent Funari, Kent D. Taylor, Phillip Fleshner, Hanlin L. Wang, Jerome I. Rotter, Quoclinh Nguyen, Christopher N. Reyes, Jordan Brown, Iliyan D. Iliev, Gordon D. Brown, Dermot P.B. McGovern, Samuel P. Strom
Publikováno v:
Science. 336:1314-1317
The Mycobiome In the past few years, much attention has been given to the trillions of bacterial inhabitants in our guts and the myriad of ways in which they influence our overall health. But what about fungi? Iliev et al. (p. 1314 ) now report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7f5fc412d49bdaabf9f4dbf202d2a8
https://doi.org/10.1126/science.1221789
https://doi.org/10.1126/science.1221789
Autor:
Margie Morgan, David M. Underhill, Waguih William IsHak, Brigitte Vanle, Joel D. Kopple, Bryan B. Shapiro, Christopher Nguyen, Courtney A. Becker, Itai Danovitch, Rebecca Hedrick
Publikováno v:
BMJ Case Reports. :bcr-2017
Cryptococcal meningitis is a life-threatening condition most commonly observed in immunocompromised individuals. We describe a daily cannabis smoker without evidence of immunodeficiency presenting with confirmed Cryptococcus neoformans meningitis. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e298deb7962b2a6c391ee3db5095bc24
https://doi.org/10.1136/bcr-2017-221435
https://doi.org/10.1136/bcr-2017-221435
Autor:
Xin Lin, Andrea J. Wolf, David M. Underhill, Courtney A. Becker, Helen S. Goodridge, Yen-Michael S. Hsu, Takahiro Shimada
Publikováno v:
The Journal of Immunology. 182:1146-1154
The pattern recognition receptors TLR2 and Dectin-1 play key roles in coordinating the responses of macrophages and dendritic cells (DC) to fungi. Induction of proinflammatory cytokines is instructed by signals from both TLR2 and Dectin-1. A recent r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd0197fce3d357a790b3ca34f22e16b
https://doi.org/10.4049/jimmunol.182.2.1146
https://doi.org/10.4049/jimmunol.182.2.1146
L chain 3 (LC3)-associated phagocytosis is a process in which LC3, a protein canonically involved in engulfing intracellular materials (autophagy), is recruited to traditional phagosomes during internalization of extracellular payloads. LC3’s assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2be7f62bd8efb28986d4483eaae1b0
https://europepmc.org/articles/PMC3966112/
https://europepmc.org/articles/PMC3966112/
Autor:
Pierre Kyme, Jun Ma, Ching Wen Tseng, Andrea J. Wolf, Amber T. Kaplan, David M. Underhill, Courtney A. Becker, George Y. Liu
The importance of type I IFNs in the host response to viral infection is well established; however, their role in bacterial infection is not fully understood. Several bacteria (both Gram-positive and -negative) have been shown to induce IFN-β produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8e282895b06c3c04358ccac8a31909
https://europepmc.org/articles/PMC3478442/
https://europepmc.org/articles/PMC3478442/