Zobrazeno 1 - 10 of 60 pro vyhledávání: '"Courtney A Crane"'
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Akademický článek
Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses
Autor: Michael C Jensen, Katherine J Brempelis, Courtney M Cowan, Shannon A Kreuser, Kevin P Labadie, Brooke M Prieskorn, Nicole A P Lieberman, Chibawanye I Ene, Kara W Moyes, Harrison Chinn, Kole R DeGolier, Lisa R Matsumoto, Sara K Daniel, Jason K Yokoyama, Amira D Davis, Virginia J Hoglund, Kimberly S Smythe, Stephanie D Balcaitis, Richard G Ellenbogen, Jean S Campbell, Eric C Holland, Courtney A Crane
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Though currently approved immunotherapies, including chimeric antigen receptor T cells and checkpoint blockade antibodies, have been successfully used to treat hematological and some solid tumor cancers, many solid tumors remain resistant
Externí odkaz: https://doaj.org/article/c3322864d2c54a13b3b2a3dea90a8cdb
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4
Akademický článek
Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases
Autor: Jennifer L. Gardell, Meghan E. Maurer, Monica M. Childs, Minh N. Pham, Brent Meengs, Susan H. Julien, Cong Tan, Daniel R. Boster, Phoenicia Quach, Jon H. Therriault, Gleda Hermansky, Daniel T. Patton, Justin Bowser, Alex Chen, Nadine N. Morgan, Emily A. Gilbertson, Lisa Bogatzki, Kaelen Encarnacion, Catherine J. McMahan, Courtney A. Crane, Kristine M. Swiderek
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionRegulatory CD8 T cells (CD8 Treg) are responsible for the selective killing of self-reactive and pathogenic CD4 T cells. In autoimmune disease, CD8 Treg may accumulate in the peripheral blood but fail to control the expansion of pathogeni
Externí odkaz: https://doaj.org/article/1178caece79b4d0e9381fbb719b41a85
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5
Supplementary Figure 2 from Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages
Autor: Andrew T. Parsa, Martin J. Rutkowski, Michael Safaee, Rajwant Kaur, Courtney A. Crane, Orin Bloch
PDF file - 42K, Figure S2. Glioma-derived soluble factors can further induce B7-H1 expression in non-autologous GBM patient peripheral monocytes, but not in autologous patient monocytes. Quantification of mean fluorescence intensity for B7-H1 stainin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ffe2cb97a5e299859319ade433f502
https://doi.org/10.1158/1078-0432.22445444.v1
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Supplementary Figure 1 from Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages
Autor: Andrew T. Parsa, Martin J. Rutkowski, Michael Safaee, Rajwant Kaur, Courtney A. Crane, Orin Bloch
PDF file - 22K, Figure S1. Glioma cells induce B7-H1 expression in peripheral monocytes from healthy donors. Monocytes from healthy donors were cultured alone in normal media or in co-culture with U251 glioma cells in contact or through a 0.2μm pore
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59efcfc55c3377511364b0bc838bb621
https://doi.org/10.1158/1078-0432.22445447
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