In vivo miR-138-5p inhibition alleviates monocrotaline-induced pulmonary hypertension and normalizes pulmonary KCNK3 and SLC45A3 expression.

Autor: Le Ribeuz, Hélène^1,2,3 (AUTHOR), Courboulin, Audrey^1,2,3 (AUTHOR), Ghigna, Maria-Rosa^1,2,3 (AUTHOR), Lambert, Mélanie^1,2,3 (AUTHOR), Hautefort, Aurélie^1,2,3 (AUTHOR), Humbert, Marc^1,2,3 (AUTHOR), Montani, David^1,2,3 (AUTHOR), Cohen-Kaminsky, Sylvia^1,2,3 (AUTHOR), Perros, Frédéric^1,2,3 (AUTHOR), Antigny, Fabrice^1,2,3 (AUTHOR) antignyfabrice@gmail.com

Publikováno v: Respiratory Research. 7/16/2020, Vol. 21 Issue 1, p1-14. 14p. 3 Color Photographs, 3 Graphs.

Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension

Autor: Paulin Roxane, Bisserier Malik, Chapolard Mathilde, Jacob Maria, Meloche Jolyane, Barrier Marjorie, Tremblay Véronique L, Courboulin Audrey, Lambert Caroline, Provencher Steeve, Bonnet Sébastien

Publikováno v: Respiratory Research, Vol 12, Iss 1, p 128 (2011)

Background Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced proliferation of pulmonary artery smooth muscle cell (PASMC) and suppressed apoptosis. This phenotype has been associated with the upregulatio

Externí odkaz: https://doaj.org/article/c46512e752354b6eb214eacbbe4f3f0f

Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.

Autor: Courboulin, Audrey¹, Tremblay, Véronique L.¹, Barrier, Marjorie, Meloche, Jolyane, Jacob, Maria Helena, Chapolard, Mathilde, Bisserier, Malik, Paulin, Roxane, Lambert, Caroline, Provencher, Steeve, Bonnet, Sébastien sebastien.bonnet@crhdq.ulaval.ca

Publikováno v: Respiratory Research. Sep2011, Vol. 12 Issue 9, p1-10. 10p. 1 Chart, 5 Graphs.

PSGR olfactory receptor: A new potential target in pulmonary arterial hypertension

Autor: Courboulin, Audrey, Quatredeniers, Marceau, Sanz, Guenhaël, Breuils-Bonnet, Sandra, Vocelle, Matthieu, Dumas, Sebastien, Lafond, Mathilde, Antigny, Fabrice, Perros, Frédéric, Dorfmüller, Peter, Fadel, Elie, Bonnet, Sébastien, Pajot, Edith, Humbert, Marc, Cohen-Kaminsky, Sylvia.

Publikováno v: ERS International Congress 2016
ERS International Congress 2016, Sep 2016, Londres, United Kingdom. 1p., 2016, ⟨10.1183/13993003.congress-2016.PA2475⟩
European Respiratory Journal
ERS International Congress 2016, Sep 2016, Londres, United Kingdom. ⟨10.1183/13993003.congress-2016.PA2475⟩
ERS International Congress 2016, Londres, GBR, 2016-09-03-2016-09-07
4.3 Pulmonary Circulation and Pulmonary Vascular Diseases. (48)2016; ERS International Congress 2016, Londres, GBR, 2016-09-03-2016-09-07, PA2475

International audience; Pulmonary arterial hypertension (PAH) is a rare progressive disease due to distal vascular remodeling, leading to right heart failure and death. PSGR is an olfactory receptor (OR) that has been recently detected in peripheral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8222078ad410eb17e56a50f47c49d8
https://doi.org/10.1183/13993003.congress-2016.pa2475

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