A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling

Autor: Abe-Jones, Yumiko, Adkisson, Michael, Ansel, K. Mark, Asthana, Saurabh, Beagle, Alexander, Bhide, Sharvari, Cai, Cathy, Caldera, Saharai, Calvo, Maria, Carrillo, Sidney A., Chak, Suzanna, Christenson, Stephanie, Collins, Zachary, Darmanis, Spyros, Detweiler, Angela, DeVoe, Catherine, Eckalbar, Walter, Giberson, Jeremy, Gonzalez, Ana, Gordon, Gracie, Serpa, Paula Hayakawa, Jauregui, Alejandra, Jones, Chayse, Ke, Serena, Kushnoor, Divya, Lea, Tasha, Lee, Deanna, Leligdowicz, Aleksandra, Liu, Yale, Mahboob, Salman, Maliskova, Lenka, Matthay, Michael, McCarthy, Elizabeth, Muñoz-Sandoval, Priscila, Neff, Norma, Nguyen, Viet, Nigam, Nishita, Parada, Randy, Phelps, Maira, Pierce, Logan, Prasad, Priya, Rashid, Sadeed, Reeder, Gabriella, Rodriguez, Nicklaus, Samad, Bushra, Schroeder, Andrew, Shaw, Cole, Shen, Alan, Sigman, Austin, Sinha, Pratik, Spitzer, Matthew, Sunshine, Sara, Tang, Kevin, Altamirano, Luz Torres, Tsitsiklis, Alexandra, Tumurbaatar, Erden, Upadhyay, Vaibhav, Whatley, Alexander, Willmore, Andrew, Wilson, Michael, Winkler, Juliane, Wong, Kristine, Yee, Kimberly, Yu, Michelle, Zhou, Mingyue, Zhu, Wandi S., Hackney, Jason A., Shivram, Haridha, Vander Heiden, Jason, Overall, Chris, Orozco, Luz, Gao, Xia, Kim, Eugene, West, Nathan, Qamra, Aditi, Chang, Diana, Chakrabarti, Arindam, Choy, David F., Combes, Alexis J., Courau, Tristan, Fragiadakis, Gabriela K., Rao, Arjun Arkal, Ray, Arja, Tsui, Jessica, Hu, Kenneth, Kuhn, Nicholas F., Krummel, Matthew F., Erle, David J., Kangelaris, Kirsten, Sarma, Aartik, Lyon, Zoe, Calfee, Carolyn S., Woodruff, Prescott G., Ghale, Rajani, Mick, Eran, Byrne, Ashley, Zha, Beth Shoshana, Langelier, Charles, Hendrickson, Carolyn M., van der Wijst, Monique G.P., Hartoularos, George C., Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Ye, Chun Jimmie, Ramalingam, Thiru, McBride, Jacqueline M., Cai, Fang, Teterina, Anastasia, Bao, Min, Tsai, Larry, Rosas, Ivan O., Regev, Aviv, Kapadia, Sharookh B., Bauer, Rebecca N., Rosenberger, Carrie M.

Publikováno v: In iScience 20 October 2023 26(10)

Activating Immune Recognition in Pancreatic Ductal Adenocarcinoma via Autophagy Inhibition, MEK Blockade, and CD40 Agonism

Autor: Jiang, Honglin, Courau, Tristan, Borison, Joseph, Ritchie, Alexa J., Mayer, Aaron T., Krummel, Matthew F., Collisson, Eric A.

Publikováno v: In Gastroenterology February 2022 162(2):590-603

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Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer

Autor: Kersten, Kelly, Hu, Kenneth H, Combes, Alexis J, Samad, Bushra, Harwin, Tory, Ray, Arja, Rao, Arjun Arkal, Cai, En, Marchuk, Kyle, Artichoker, Jordan, Courau, Tristan, Shi, Quanming, Belk, Julia, Satpathy, Ansuman T, Krummel, Matthew F

Publikováno v: Cancer cell, vol 40, iss 6

T cell exhaustion is a major impediment to antitumor immunity. However, it remains elusive how other immune cells in the tumor microenvironment (TME) contribute to this dysfunctional state. Here, we show that the biology of tumor-associated macrophag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::50774ddfeed395f012ae9becba4775c3
https://escholarship.org/uc/item/2nh5c95p

Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition.

Autor: Bonnereau, Julie, Courau, Tristan, Asesio, Nicolas, Salfati, Delphine, Bouhidel, Fatiha, Corte, Hélène, Hamoudi, Sarah, Hammoudi, Nassim, Lavolé, Julie, Vivier-Chicoteau, Justine, Chardiny, Victor, Maggiori, Leon, Blery, Mathieu, Remark, Romain, Bonnafous, Cécile, Cattan, Pierre, Toubert, Antoine, Bhat, Purnima, Allez, Matthieu, Aparicio, Thomas

Publikováno v: Gut; Apr2023, Vol. 72 Issue 4, p699-709, 11p