Synthesis and screening of a library of Lewis^x deoxyfluoro-analogues reveals differential recognition by glycan-binding partners.

Autor: Hollingsworth, Kristian, Di Maio, Antonio, Richards, Sarah-Jane, Vendeville, Jean-Baptiste, Wheatley, David E., Council, Claire E., Keenan, Tessa, Ledru, Hélène, Chidwick, Harriet, Huang, Kun, Parmeggiani, Fabio, Marchesi, Andrea, Chai, Wengang, McBerney, Ryan, Kamiński, Tomasz P., Balmforth, Matthew R., Tamasanu, Alexandra, Finnigan, James D., Young, Carl, Warriner, Stuart L.

Publikováno v: Nature Communications; 9/14/2024, Vol. 15 Issue 1, p1-14, 14p

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The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity

Autor: Butler, John, Smyth, Neil, Broadbridge, Robert, Council, Claire E., Lee, Anthony G., Stocker, Claire J., Hislop, David C., Arch, Jonathan R.S., Cawthorne, Michael A., Malcolm East, J.

Studies in sarcolipin knockout mice have led to the suggestion that skeletal muscle sarcolipin plays a role in thermogenesis. The mechanism proposed is uncoupling of the sarcoplasmic reticulum calcium pump. However, in other work sarcolipin was not d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9500e43437b72931c5a511e3f6285737
https://eprints.soton.ac.uk/377092/

Synthesis and screening of a library of Lewis ^x deoxyfluoro-analogues reveals differential recognition by glycan-binding partners.

Autor: Hollingsworth K; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Di Maio A; Glycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Richards SJ; Department of Chemistry, University of Warwick, Coventry, UK.; Manchester Institute of Biotechnology (MIB), Department of Chemistry, University of Manchester, Manchester, UK., Vendeville JB; School of Chemistry, University of Southampton, Highfield, Southampton, UK., Wheatley DE; School of Chemistry, University of Southampton, Highfield, Southampton, UK., Council CE; School of Chemistry, University of Southampton, Highfield, Southampton, UK., Keenan T; Department of Chemistry, University of York, Heslington, York, UK., Ledru H; School of Chemistry, Cantock's Close, University of Bristol, Bristol, UK., Chidwick H; Department of Chemistry, University of York, Heslington, York, UK., Huang K; Manchester Institute of Biotechnology (MIB), Department of Chemistry, University of Manchester, Manchester, UK., Parmeggiani F; Manchester Institute of Biotechnology (MIB), Department of Chemistry, University of Manchester, Manchester, UK., Marchesi A; Manchester Institute of Biotechnology (MIB), Department of Chemistry, University of Manchester, Manchester, UK., Chai W; Glycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., McBerney R; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Kamiński TP; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Balmforth MR; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Tamasanu A; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Finnigan JD; Prozomix Limited, Haltwhistle Industrial Estate, Haltwhistle, Northumberland, UK., Young C; Prozomix Limited, Haltwhistle Industrial Estate, Haltwhistle, Northumberland, UK., Warriner SL; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Webb ME; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Fascione MA; Department of Chemistry, University of York, Heslington, York, UK., Flitsch S; Manchester Institute of Biotechnology (MIB), Department of Chemistry, University of Manchester, Manchester, UK., Galan MC; School of Chemistry, Cantock's Close, University of Bristol, Bristol, UK., Feizi T; Glycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK. t.feizi@imperial.ac.uk., Gibson MI; Department of Chemistry, University of Warwick, Coventry, UK. matt.gibson@manchester.ac.uk.; Manchester Institute of Biotechnology (MIB), Department of Chemistry, University of Manchester, Manchester, UK. matt.gibson@manchester.ac.uk.; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK. matt.gibson@manchester.ac.uk., Liu Y; Glycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK. yan.liu2@imperial.ac.uk., Turnbull WB; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK. W.B.Turnbull@leeds.ac.uk., Linclau B; School of Chemistry, University of Southampton, Highfield, Southampton, UK. bruno.linclau@ugent.be.; Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium. bruno.linclau@ugent.be.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 13; Vol. 15 (1), pp. 7925. Date of Electronic Publication: 2024 Sep 13.

The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity.

Autor: Butler J; Centre for Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK., Smyth N; Centre for Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK., Broadbridge R; Peptide Protein Research Ltd, 184 Funtley Road, Fareham PO15 6DP, UK., Council CE; Peptide Protein Research Ltd, 184 Funtley Road, Fareham PO15 6DP, UK., Lee AG; Centre for Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK., Stocker CJ; The Clore Laboratory, University of Buckingham, Buckingham MK18 1EG, UK., Hislop DC; The Clore Laboratory, University of Buckingham, Buckingham MK18 1EG, UK., Arch JR; The Clore Laboratory, University of Buckingham, Buckingham MK18 1EG, UK., Cawthorne MA; The Clore Laboratory, University of Buckingham, Buckingham MK18 1EG, UK., Malcolm East J; Centre for Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK. Electronic address: jme1@soton.ac.uk.

Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2015 Mar 01; Vol. 569, pp. 26-31. Date of Electronic Publication: 2015 Feb 07.