Balancing Clinical Applicability and Scientific Depth in ML Models for MDA5-DM Prognosis.

Autor: McLeish E; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, Western Australia (WA), Australia., Slater N; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, Western Australia (WA), Australia., Mastaglia FL; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia., Needham M; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, Western Australia (WA), Australia.; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia.; University of Notre Dame Australia, School of Medicine, Fremantle, WA, Australia.; Fiona Stanley Hospital, Department of Neurology, Murdoch, WA, Australia., Coudert JD; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, Western Australia (WA), Australia.; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia.; University of Notre Dame Australia, School of Medicine, Fremantle, WA, Australia.

Publikováno v: Briefings in bioinformatics [Brief Bioinform] 2024 May 23; Vol. 25 (4).

High-resolution HLA genotyping in inclusion body myositis refines 8.1 ancestral haplotype association to DRB1*03:01:01 and highlights pathogenic role of arginine-74 of DRβ1 chain.

Autor: Slater N; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, WA, Australia., Sooda A; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, WA, Australia., McLeish E; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, WA, Australia., Beer K; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, WA, Australia; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia., Brusch A; PathWest Laboratory Medicine, Dept of Clinical Immunology, QEII Medical Centre, Nedlands, WA, Australia., Shakya R; PathWest Laboratory Medicine, Dept of Clinical Immunology, QEII Medical Centre, Nedlands, WA, Australia., Bundell C; PathWest Laboratory Medicine, Dept of Clinical Immunology, QEII Medical Centre, Nedlands, WA, Australia., James I; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia; Murdoch University, Institute for Immunology and Infection Diseases, Murdoch, WA, Australia., Chopra A; Murdoch University, Institute for Immunology and Infection Diseases, Murdoch, WA, Australia., Mastaglia FL; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia; University of Western Australia, Centre for Neuromuscular & Neurological Disorders, Crawley, WA, Australia., Needham M; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, WA, Australia; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia; University of Notre Dame Australia, School of Medicine, Fremantle, WA, Australia; Fiona Stanley Hospital, Department of Neurology, Murdoch, WA, Australia., Coudert JD; Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch, WA, Australia; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia; University of Notre Dame Australia, School of Medicine, Fremantle, WA, Australia. Electronic address: jerome.coudert@murdoch.edu.au.

Publikováno v: Journal of autoimmunity [J Autoimmun] 2024 Jan; Vol. 142, pp. 103150. Date of Electronic Publication: 2023 Dec 02.

Testosterone treatment combined with exercise to improve muscle strength, physical function and quality of life in men affected by inclusion body myositis: A randomised, double-blind, placebo-controlled, crossover trial.

Autor: Connor SG; Royal Perth Hospital, Perth, Western Australia, Australia., Fairchild TJ; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Discipline of Exercise Science, Murdoch University, Murdoch, Western Australia, Australia., Learmonth YC; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Discipline of Exercise Science, Murdoch University, Murdoch, Western Australia, Australia.; Perron Institute of Neurological and Translational Sciences, Nedlands, Western Australia, Australia., Beer K; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Perron Institute of Neurological and Translational Sciences, Nedlands, Western Australia, Australia., Cooper I; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Perron Institute of Neurological and Translational Sciences, Nedlands, Western Australia, Australia., Boardman G; Research Development Unit, Fiona Stanley Hospital, Murdoch, Western Australia, Australia., Teo SYM; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Discipline of Exercise Science, Murdoch University, Murdoch, Western Australia, Australia., Shatahmasseb B; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Discipline of Exercise Science, Murdoch University, Murdoch, Western Australia, Australia., Zhang R; Department of Clinical Biochemistry, Pharmacology and Toxicology, PathWest Laboratory Medicine, QEII Medical Centre, Nedlands, WA, Australia., Hiscock K; Affinity Clinical Research, Nedlands, Western Australia, Australia., Coudert JD; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Perron Institute of Neurological and Translational Sciences, Nedlands, Western Australia, Australia.; Division of Medicine, The University of Notre Dame Australia, Fremantle, Western Australia, Australia., Yeap BB; Department of Endocrinology and Diabetes, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.; Medical School, University of Western Australia, Crawley, Western Australia, Australia., Needham M; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia.; Perron Institute of Neurological and Translational Sciences, Nedlands, Western Australia, Australia.; Division of Medicine, The University of Notre Dame Australia, Fremantle, Western Australia, Australia.; Department of Neurology, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.

Publikováno v: PloS one [PLoS One] 2023 Apr 11; Vol. 18 (4), pp. e0283394. Date of Electronic Publication: 2023 Apr 11 (Print Publication: 2023).

Immunoregulatory effects of testosterone supplementation combined with exercise training in men with Inclusion Body Myositis: a double-blind, placebo-controlled, cross-over trial.

Autor: Coudert JD; Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Murdoch WA Australia.; Perron Institute for Neurological and Translational Science Nedlands WA Australia.; School of Medicine University of Notre Dame Fremantle WA Australia., Slater N; Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Murdoch WA Australia., Sooda A; Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Murdoch WA Australia., Beer K; Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Murdoch WA Australia.; Perron Institute for Neurological and Translational Science Nedlands WA Australia., Lim EM; Department of Clinical Biochemistry, Pharmacology and Toxicology, PathWest Laboratory Medicine QEII Medical Centre Nedlands WA Australia., Boyder C; Department of Clinical Biochemistry, Pharmacology and Toxicology, PathWest Laboratory Medicine QEII Medical Centre Nedlands WA Australia., Zhang R; Department of Clinical Biochemistry, Pharmacology and Toxicology, PathWest Laboratory Medicine QEII Medical Centre Nedlands WA Australia., Mastaglia FL; Perron Institute for Neurological and Translational Science Nedlands WA Australia., Learmonth YC; Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Murdoch WA Australia.; Perron Institute for Neurological and Translational Science Nedlands WA Australia.; Discipline of Exercise Science Murdoch University Murdoch WA Australia., Fairchild TJ; Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Murdoch WA Australia.; Discipline of Exercise Science Murdoch University Murdoch WA Australia., Yeap BB; Medical School University of Western Australia Perth WA Australia.; Department of Endocrinology and Diabetes Fiona Stanley Hospital Perth WA Australia., Needham M; Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Murdoch WA Australia.; Perron Institute for Neurological and Translational Science Nedlands WA Australia.; School of Medicine University of Notre Dame Fremantle WA Australia.; Department of Neurology Fiona Stanley Hospital Perth WA Australia.

Publikováno v: Clinical & translational immunology [Clin Transl Immunology] 2022 Sep 22; Vol. 11 (9), pp. e1416. Date of Electronic Publication: 2022 Sep 22 (Print Publication: 2022).

Isolation of Live Leukocytes from Human Inflammatory Muscles.

Autor: Coudert JD; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia.; Perron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.; School of Medicine, University of Notre Dame, Fremantle, WA 6160, Australia., McLeish E; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia., Sooda A; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia., Slater N; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia., Beer K; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia.; Perron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia., Paramalingam S; Department of Rheumatology, Fiona Stanley Hospital, Murdoch, WA 6150, Australia., Lamont PJ; Neurogenetic Unit, Royal Perth Hospital, Perth, WA 6000, Australia., Needham M; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA 6150, Australia.; School of Medicine, University of Notre Dame, Fremantle, WA 6160, Australia.; Department of Neurology, Fiona Stanley Hospital, Murdoch, WA 6150, Australia.

Publikováno v: Methods and protocols [Methods Protoc] 2021 Oct 16; Vol. 4 (4). Date of Electronic Publication: 2021 Oct 16.