Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins.

Autor: Pance K; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; EpiBiologics, Inc., San Carlos, CA, USA., Gramespacher JA; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; EpiBiologics, Inc., San Carlos, CA, USA., Byrnes JR; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Salangsang F; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.; Preclinical Therapeutics Core, University of California San Francisco, San Francisco, CA, USA., Serrano JC; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.; Preclinical Therapeutics Core, University of California San Francisco, San Francisco, CA, USA., Cotton AD; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Steri V; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.; Preclinical Therapeutics Core, University of California San Francisco, San Francisco, CA, USA., Wells JA; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA. jim.wells@ucsf.edu.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA. jim.wells@ucsf.edu.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2023 Feb; Vol. 41 (2), pp. 273-281. Date of Electronic Publication: 2022 Sep 22.

Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.

Autor: Tolani B; Thoracic Oncology Program, Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA. Bhairavi.Tolani@ucsf.edu., Celli A; Laboratory for Cell Analysis Core Facility, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Yao Y; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, CA, USA., Tan YZ; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.; Disease Intervention Technology Laboratory, Agency for Science, Technology and Research, Singapore, Singapore., Fetter R; Howard Hughes Medical Institute, Department of Biology, Stanford University, Stanford, CA, USA., Liem CR; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Division of Biological Sciences, the Section of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, USA., de Smith AJ; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA., Vasanthakumar T; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Biochemistry, The University of Toronto, Toronto, ON, Canada., Bisignano P; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, CA, USA., Cotton AD; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, CA, USA., Seiple IB; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, CA, USA., Rubinstein JL; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Biochemistry, The University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, The University of Toronto, Toronto, ON, Canada., Jost M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA. marco_jost@hms.harvard.edu.; Department of Microbiology & Immunology, University of California, San Francisco, CA, USA. marco_jost@hms.harvard.edu.; Department of Microbiology, Harvard Medical School, Boston, MA, USA. marco_jost@hms.harvard.edu., Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2022 Dec; Vol. 40 (12), pp. 1834-1844. Date of Electronic Publication: 2022 Jul 25.

Examining Gender Imbalance in Chemistry Authorship.

Autor: Cotton AD; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States., Seiple IB; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States.; Cardiovascular Research Institute, University of California, San Francisco, California 94143, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2021 Nov 19; Vol. 16 (11), pp. 2042-2046. Date of Electronic Publication: 2021 Sep 15.