Development of a long-acting relaxin analogue, LY3540378, for treatment of chronic heart failure.

Autor: Verdino P; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Lee SL; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Cooper FN; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Cottle SR; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Grealish PF; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Hu CC; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Meyer CM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Lin J; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Copeland V; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Porter G; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Schroeder RL; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Thompson TD; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Porras LL; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Dey A; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Zhang HY; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Beebe EC; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Matkovich SJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Coskun T; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Balciunas AM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Ferrante A; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Siegel R; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Malherbe L; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Bivi N; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Paavola CD; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Hansen RJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Abernathy MM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Nwosu SO; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Carr MC; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Heuer JG; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Wang X; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2023 Aug; Vol. 180 (15), pp. 1965-1980. Date of Electronic Publication: 2023 Mar 08.