Exploring the 1-(4-Nitrophenyl)-3-arylprop-2-en-1-one Scaffold for the Selective Inhibition of Monoamine Oxidase B.

Autor: Meleddu R; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Fais A; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Era B; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Floris S; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Distinto S; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Lupia A; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy.; Net4Science Srl, University 'Magna Græcia', Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro Italy., Cottiglia F; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Onali A; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Sanna E; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Secci D; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Atzeni G; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Demuru L; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Caboni P; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Valenti D; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy., Maccioni E; Department of Life and Environmental Sciences, University of Cagliari, University Campus, S.P. 8 km 0.700, 09042 Monserrato, Italy.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Sep 27; Vol. 15 (10), pp. 1685-1691. Date of Electronic Publication: 2024 Sep 27 (Print Publication: 2024).

Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea .

Autor: Huang SW; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Department of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan., Hsu MJ; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan., Chen HC; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Meleddu R; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Distinto S; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Maccioni E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Cottiglia F; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2287420. Date of Electronic Publication: 2023 Dec 07.

2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms.

Autor: Sequeira L; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.; CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal., Distinto S; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy., Meleddu R; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy., Gaspari M; Department of Experimental and Clinical Medicine, Research Centre for Advanced Biochemistry and Molecular Biology, 'Magna Græcia' University of Catanzaro, Catanzaro, Italy., Angeli A; Department of NEUROFARBA, Section of Pharmaceutical Sciences, University of Florence, Florence, Italy., Cottiglia F; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy., Secci D; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy., Onali A; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy., Sanna E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy., Borges F; CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal., Uriarte E; Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain., Alcaro S; Department of Health Sciences, 'Magna Græcia' University of Catanzaro, Catanzaro, Italy., Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical Sciences, University of Florence, Florence, Italy., Maccioni E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2270183. Date of Electronic Publication: 2023 Oct 23.

Effects of docosanyl ferulate, a constituent of Withania somnifera, on ethanol- and morphine-elicited conditioned place preference and ERK phosphorylation in the accumbens shell of CD1 mice.

Autor: Maccioni R; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy., Serra M; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Marongiu J; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Cottiglia F; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy., Maccioni E; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy., Bassareo V; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.; Center of Excellence for the Study of Neurobiology of Addiction, University of Cagliari, Cagliari, Italy., Morelli M; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.; Center of Excellence for the Study of Neurobiology of Addiction, University of Cagliari, Cagliari, Italy., Kasture SB; Pinnacle Biomedical Research Institute, Bhopal, India., Acquas E; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy. acquas@unica.it.; Center of Excellence for the Study of Neurobiology of Addiction, University of Cagliari, Cagliari, Italy. acquas@unica.it.

Publikováno v: Psychopharmacology [Psychopharmacology (Berl)] 2022 Mar; Vol. 239 (3), pp. 795-806. Date of Electronic Publication: 2022 Jan 28.

Flavonoids and Acid-Hydrolysis derivatives of Neo -Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase-associated RNase H function.

Autor: Fois B; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Corona A; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Tramontano E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy.; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Monserrato, Italy., Distinto S; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Maccioni E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Meleddu R; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Caboni P; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy., Floris C; Department of Chemical and Geological Sciences, University of Cagliari, Monserrato, Italy., Cottiglia F; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Italy.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 749-757.