Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

Autor: Barrett, JC, Lee, JC, Lees, CW, Prescott, NJ, Anderson, CA, Phillips, A, Wesley, E, Parnell, K, Zhang, H, Drummond, H, Nimmo, ER, Massey, D, Blaszczyk, K, Elliott, T, Cotterill, L, Dallal, H, Lobo, AJ, Mowat, C, Sanderson, JD, Jewell, DP, Newman, WG, Edwards, C, Ahmad, T, Mansfield, JC, Satsangi, J, Parkes, M, Mathew, CG, Donnelly, P, Peltonen, L, Blackwell, JM, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Craddock, N, Deloukas, P, Duncanson, A, Jankowski, J, Markus, HS, McCarthy, MI, Palmer, CN, Plomin, R, Rautanen, A, Sawcer, SJ, Samani, N, Trembath, RC, Viswanathan, AC, Wood, N, Spencer, CC, Bellenguez, C, Davison, D, Freeman, C, Strange, A, Langford, C, Hunt, SE, Edkins, S, Gwilliam, R, Blackburn, H, Bumpstead, SJ, Dronov, S, Gillman, M, Gray, E, Hammond, N, Jayakumar, A, McCann, OT, Liddle, J, Perez, ML, Potter, SC, Ravindrarajah, R, Ricketts, M, Waller, M, Weston, P, Widaa, S, Whittaker, P, Attwood, AP, Stephens, J, Sambrook, J, Ouwehand, WH, McArdle, WL, Ring, SM, Strachan, DP

Publikováno v: Barrett, J C, Lee, J C, Lees, C W, Prescott, N J, Anderson, C A, Phillips, A, Wesley, E, Parnell, K, Zhang, H, Drummond, H, Nimmo, E R, Massey, D, Blaszczyk, K, Elliott, T, Cotterill, L, Dallal, H, Lobo, A J, Mowat, C, Sanderson, J D, Jewell, D P, Newman, W G, Edwards, C, Ahmad, T, Mansfield, J C, Satsangi, J, Parkes, M, Mathew, C G, Donnelly, P, Peltonen, L, Blackwell, J M, Bramon, E, Brown, M A, Casas, J P, Corvin, A, Craddock, N, Deloukas, P, Duncanson, A, Jankowski, J, Markus, H S, McCarthy, M I, Palmer, C N A, Plomin, R, Rautanen, A, Sawcer, S J, Samani, N, Trembath, R C, Viswanathan, A C, Wood, N, Spencer, C C A, Bellenguez, C 2009, ' Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region ', Nature Genetics, vol. 41, no. 12, pp. 1330-U99 . https://doi.org/10.1038/ng.483

Ulcerative colitis is a common form of inflammatory bowel disease with a complex etiology. As part of the Wellcome Trust Case Control Consortium 2, we performed a genome-wide association scan for ulcerative colitis in 2,361 cases and 5,417 controls.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0990a49301742dbc4a4ff13275330ba1
https://hdl.handle.net/20.500.11820/f4c40200-7b25-40e8-9144-3c9245522e28

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The Importance of Iron, Calcium and Free Radicals in Reperfusion Injury: An Overview of Studies in Ischaemic Rabbit Kidneys.

Autor: Green, C. J., Gower, J. D., Healing, G., Cotterill, L. A., Fuller, B. J., Simpkin, S.

Publikováno v: Free Radical Research Communications; 1989, Vol. 7 Issue 3-6, p255-264, 10p