Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cottell, Jeromy J."'
Autor:
Cheng Y. Yang, Cottell Jeromy J, Krygowski Evan S, Jason K. Perry, Katana Ashley Anne, Mei Yu, Yujin Wang, Tran Chinh Viet, Guangyu Zhao, Yang Zheng-Yu, Kelly Wang, Yu-Jen Lee, Ruoyu Gong, Eric M. Gorman, Alejandra Trejo-Martin, Yang Tian, Kato Darryl, Erik Mogalian, Bacon Elizabeth M, Link John O, James G. Taylor, Guofeng Cheng, Zipfel Sheila
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2415-2427
Direct-acting antiviral inhibitors have revolutionized the treatment of hepatitis C virus (HCV) infected patients. Herein is described the discovery of velpatasvir (VEL, GS-5816), a potent pan-genotypic HCV NS5A inhibitor that is a component of the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e1fbe8045531556d55ed210cd6fe2a
https://doi.org/10.1016/j.bmcl.2019.04.027
https://doi.org/10.1016/j.bmcl.2019.04.027
Publikováno v:
Medicinal Chemistry Reviews ISBN: 9780996293280
Medicinal Chemistry Reviews
Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2afebe7f82853f290df2cfec3bedf5ef
https://doi.org/10.29200/acsmedchemrev-v54.ch5
https://doi.org/10.29200/acsmedchemrev-v54.ch5
Autor:
Link, John O., Taylor, James G., Trejo-Martin, Alejandra, Kato, Darryl, Katana, Ashley A., Krygowski, Evan S., Yang, Zheng-Yu, Zipfel, Sheila, Cottell, Jeromy J., Bacon, Elizabeth M., Tran, Chinh V., Yang, Cheng Y., Wang, Yujin, Wang, Kelly W., Zhao, Guangyu, Cheng, Guofeng, Tian, Yang, Gong, Ruoyu, Lee, Yu-Jen, Yu, Mei, Gorman, Eric, Mogalian, Erik, Perry, Jason K.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 August 2019 29(16):2415-2427
Autor:
Michael O'neil Hanrahan Clarke, Jie Xu, Edward Doerffler, Todd Appleby, X. Christopher Sheng, Choung U. Kim, Thomas Butler, John O. Link, William E. Delaney, Mingzhe Ji, Xiaowu Chen, Ruby Cai, Cottell Jeromy J, Hyung-Jung Pyun, Wu Qiaoyin, Aesop Cho, Rowchanak Pakdaman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:2629-2634
The discovery of GS-9451 is reported. Modification of the P3 cap and P2 quinoline with a series of solubilizing groups led to the identification of potent HCV NS3 protease inhibitors with greatly improved pharmacokinetic properties in rats, dogs and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbcd382ed18dee42da2aee6745d1328
https://doi.org/10.1016/j.bmcl.2012.01.017
https://doi.org/10.1016/j.bmcl.2012.01.017
Akademický článek
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Autor:
Denmark, Scott E., Cottell, Jeromy J.
Publikováno v:
Journal of Organic Chemistry; 06/15/2001, Vol. 66 Issue 12, p4276, 9p, 14 Diagrams, 2 Charts
Autor:
Denmark, Scott E., Cottell, Jeromy J.
Publikováno v:
ChemInform; Jun2003, Vol. 34 Issue 25, pno-no, 1p