Zobrazeno 1 - 10
of 1 050
pro vyhledávání: '"Cotman, CW"'
Publikováno v:
Carlos, AJ; Tong, L; Prieto, GA; & Cotman, CW. (2017). IL-1 beta impairs retrograde flow of BDNF signaling by attenuating endosome trafficking. JOURNAL OF NEUROINFLAMMATION, 14. doi: 10.1186/s12974-017-0803-z. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9qh2030p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::6ad61598e22b8492fac26620ca08cb73
http://www.escholarship.org/uc/item/9qh2030p
http://www.escholarship.org/uc/item/9qh2030p
Autor:
Winchester, J, Dick, MB, Gillen, D, Reed, B, Miller, B, Tinklenberg, J, Mungas, D, Chui, H, Galasko, D, Hewett, L, Cotman, CW
Publikováno v:
Archives of gerontology and geriatrics, vol 56, iss 1
AD is a public health epidemic, which seriously impacts cognition, mood and daily activities; however, one type of activity, exercise, has been shown to alter these states. Accordingly, we sought to investigate the relationship between exercise and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::a64423c89172fab6483cf745e922ce81
https://escholarship.org/uc/item/0r02t3fz
https://escholarship.org/uc/item/0r02t3fz
Publikováno v:
Jung, KM; Astarita, G; Yasar, S; Vasilevko, V; Cribbs, DH; Head, E; et al.(2012). An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. Neurobiology of Aging, 33(8), 1522-1532. doi: 10.1016/j.neurobiolaging.2011.03.012. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9cc2c8m4
The endocannabinoids and their attending cannabinoid (CB)1receptors have been implicated in the control of cognition, but their possible roles in dementias are still unclear. In the present study, we used liquid chromatography/mass spectrometry to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::da3e3b4f06312ae5389e2a49054c8b4d
http://www.escholarship.org/uc/item/9cc2c8m4
http://www.escholarship.org/uc/item/9cc2c8m4
Publikováno v:
Snigdha, S; Astarita, G; Piomelli, D; & Cotman, CW. (2012). Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. Neuroscience, 202, 326-333. doi: 10.1016/j.neuroscience.2011.12.002. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3c48d531
Despite several recent studies suggesting that dysregulation of brain lipid metabolism might contribute to the mechanisms of aging and Alzheimer's disease (AD), lipid metabolism has not been evaluated extensively in the aging brain. Here, we use a li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::97aacced851c491b0035cc17443cff9f
http://www.escholarship.org/uc/item/3c48d531
http://www.escholarship.org/uc/item/3c48d531
Autor:
Naj, AC, Jun, G, Beecham, GW, Wang, LS, Vardarajan, BN, Buros, J, Gallins, PJ, Buxbaum, JD, Jarvik, GP, Crane, PK, Larson, EB, Bird, TD, Boeve, BF, Graff-Radford, NR, De Jager, PL, Evans, D, Schneider, JA, Carrasquillo, MM, Ertekin-Taner, N, Younkin, SG, Cruchaga, C, Kauwe, JSK, Nowotny, P, Kramer, P, Hardy, J, Huentelman, MJ, Myers, AJ, Barmada, MM, Demirci, FY, Baldwin, CT, Green, RC, Rogaeva, E, George-Hyslop, PS, Arnold, SE, Barber, R, Beach, T, Bigio, EH, Bowen, JD, Boxer, A, Burke, JR, Cairns, NJ, Carlson, CS, Carney, RM, Carroll, SL, Chui, HC, Clark, DG, Corneveaux, J, Cotman, CW, Cummings, JL, Decarli, C, Dekosky, ST, Diaz-Arrastia, R, Dick, M, Dickson, DW, Ellis, WG, Faber, KM, Fallon, KB, Farlow, MR, Ferris, S, Frosch, MP, Galasko, DR, Ganguli, M, Gearing, M, Geschwind, DH, Ghetti, B, Gilbert, JR, Gilman, S, Giordani, B, Glass, JD, Growdon, JH, Hamilton, RL, Harrell, LE, Head, E, Honig, LS, Hulette, CM, Hyman, BT, Jicha, GA, Jin, LW, Johnson, N, Karlawish, J, Karydas, A, Kaye, JA, Kim, R
Publikováno v:
Naj, AC; Jun, G; Beecham, GW; Wang, LS; Vardarajan, BN; Buros, J; et al.(2011). Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics, 43(5), 436-443. doi: 10.1038/ng.801. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6xc596k3
The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association study of late-onset Alzheimer disease using a three-stage design consisting of a discovery stage (stage 1) and two replication stages (stages 2 and 3). Both joint an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9f53ff000ffc5d3502416acdaff6517b
http://www.escholarship.org/uc/item/6xc596k3
http://www.escholarship.org/uc/item/6xc596k3
Autor:
Mulnard, RA, Cotman, CW, Kawas, C, Van Dyck, CH, Sano, M, Doody, R, Koss, E, Pfeiffer, E, Jin, S, Gamst, A, Grundman, M, Thomas, R, Thal, LJ
Publikováno v:
Mulnard, RA; Cotman, CW; Kawas, C; Van Dyck, CH; Sano, M; Doody, R; et al.(2000). Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: A randomized controlled trial. Journal of the American Medical Association, 283(8), 1007-1015. doi: 10.1001/jama.283.8.1007. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1v73t255
Context: Several reports from small clinical trials have suggested that estrogen replacement therapy may be useful for the treatment of Alzheimer disease (AD) in women. Objective: To determine whether estrogen replacement therapy affects-global, cogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::495f85599e9e264f39af3f0cf4d940b0
http://www.escholarship.org/uc/item/1v73t255
http://www.escholarship.org/uc/item/1v73t255
Publikováno v:
Neuroreport. 4(1)
Transforming growth factor-beta (TGF-beta) is a major modulator of the extracellular matrix and cell growth, and shows affinity for and interaction with several substances present in plaques in Alzheimer's disease (AD). In order to examine a possible
Akademický článek
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Akademický článek
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