Zobrazeno 1 - 10
of 1 112
pro vyhledávání: '"Costunolide"'
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Ulcerative colitis (UC) is a persistent inflammatory condition that specifically targets the colon and rectum. Existing therapies fail to adequately address the clinical requirements of people suffering from this ailment. Despite the acknowl
Externí odkaz:
https://doaj.org/article/ba21569a923349489b0437455ac68a06
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 2693-2712 (2024)
Yang Zhao,1,* Yi-Han Wang,2,* Wei-Chao Tu,1 Da-Wei Wang,1 Mu-Jun Lu,3,4 Yuan Shao1 1Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, 201800, People’s Republic of China; 2Departme
Externí odkaz:
https://doaj.org/article/ed93b4774ef94ce9b5493b32dcf9713b
Autor:
Alaa Sirwi, Nesrine S. El-Sayed, Dina A.I. Albadawi, Abdulrahman E. Koshak, Sabrin R.M. Ibrahim, Gamal A. Mohamed, Hossam M. Abdallah, Mostafa A. Rabie
Publikováno v:
Scientific African, Vol 26, Iss , Pp e02470- (2024)
Costunolide (COST), a sesquiterpene lactone, has demonstrated promising potential in molecular docking studies targeting key proteins associated with Parkinson's disease (PD), particularly AMP-activated protein kinase (AMPK) and sirtuin-1 (SIRT1). Bu
Externí odkaz:
https://doaj.org/article/5fcd520b81af4888a9e47a3dc30bde7f
Autor:
Mohammed Aldholmi
Publikováno v:
Ultrasonics Sonochemistry, Vol 111, Iss , Pp 107128- (2024)
Dolomiaea costus, commonly known as Indian costus, is a medicinal plant from the Asteraceae family. The root and powder of costus have been widely used to treat various health conditions. The primary bioactive compounds in this plant are sesquiterpen
Externí odkaz:
https://doaj.org/article/07d59b497451447baa0d17cc03e48908
Autor:
Duraipandiyan Veeramuthu, Ignacimuthu Savarimuthu, Inshad Ali Khan, Hissah Abdulrahman Alodaini, Ashraf Atef Hatamleh, Stalin Antony
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 9, Pp 103351- (2024)
Emergence of multidrug resistant strains of Mycobacterium tuberculosis is globally threatening the world and creating problems for the management of tuberculosis (TB). Traditional medicine and plant secondary metabolites are playing an important role
Externí odkaz:
https://doaj.org/article/9b0347be7d574ed5b8a0daf102c380d0
Autor:
Mustafa Güler, Ayhan Tanyeli, Ersen Eraslan, Özgür Çelebi, Demet Çelebi, Selim Çomakli, Emir Yurdgülü, Yasin Bayir
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 5, Pp 567-576 (2024)
Objective(s): Sepsis poses a significant threat to human life, rendering it a burdensome medical disease. Despite significant advancements, the current state of medical science still lacks a viable and efficacious cure. Costunolide (COST) is a multif
Externí odkaz:
https://doaj.org/article/7661d990d81642babc4ced051ead6493
Akademický článek
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Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 10, Pp 1168-1176 (2023)
Objective(s): Renal ischemia-reperfusion (I/R) is a vital health condition leading to acute kidney injury. Costunolide (COST) is an actively used molecule clinically for its anti-inflammatory, antioxidant, and immunomodulatory properties. In the pres
Externí odkaz:
https://doaj.org/article/e4a8085f1a01486c9ec99a0fa45b1c1a
Autor:
Juan Hao, Xiaoyu Shen, Kan Lu, Yi Xu, Yiyue Chen, Jibo Liu, Xiaohong Shao, Chunling Zhu, Yaqin Ding, Xin Xie, Jian Wu, Quanjun Yang
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 13, Iss 4, Pp 345-357 (2023)
Purpose: Cholestatic liver diseases are groups of hepatobiliary diseases without curative drug-based therapy options. Regulation of bile acid (BA) metabolism, hepatoperiductal fibrosis, and inflammatory response indicated present novel methods for th
Externí odkaz:
https://doaj.org/article/364966b0138e4616be681a7d643e0394
Publikováno v:
Molecules, Vol 29, Iss 8, p 1866 (2024)
Alantolactone is a eudesmane-type sesquiterpene lactone containing an α-methylene-γ-lactone moiety. Previous studies showed that alantolactone inhibits the nuclear factor κB (NF-κB) signaling pathway by targeting the inhibitor of NF-κB (IκB) ki
Externí odkaz:
https://doaj.org/article/244aa3e446cd4190ada317cedcc1314b