Zobrazeno 1 - 10
of 2 345
pro vyhledávání: '"Costimulatory molecules"'
Autor:
Sulayne Janayna Araujo Guimarães, André Alvares Marques Vale, Mirtes Castelo Branco Rocha, Ana Luiza de Araújo Butarelli, Jenilson Mota da Silva, Amanda Jordão Silva de Deus, Leudivan Nogueira, Ronald Wagner Pereira Coelho, Silma Regina Pereira, Ana Paula Silva Azevedo-Santos
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Penile squamous cell carcinoma (PSCC) is a largely neglected condition, predominantly affecting underdeveloped regions, and is associated with risk factors such as low socioeconomic status, phimosis, and human papillomavirus (HPV) infection. Unlike o
Externí odkaz:
https://doaj.org/article/cc02071462e14b76af319d3cd19c97bf
Autor:
Chao Zhang, Wenyu Zhai, Yuyu Ma, Minqing Wu, Qiaoting Cai, Jiajia Huang, Zhihuan Zhou, Fangfang Duan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCostimulatory molecules are putative novel targets or potential additions to current available immunotherapy, but their expression patterns and clinical value in triple-negative breast cancer (TNBC) are to be clarified. MethodsThe gene ex
Externí odkaz:
https://doaj.org/article/10c92e76d1fe4700acb043dba95b12d8
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionAutoimmune diseases result from the loss of immune tolerance, and they exhibit complex pathogenic mechanisms that remain challenging to effectively treat. It has been reported that the altered expression levels of co-stimulatory/inhibitor
Externí odkaz:
https://doaj.org/article/7406338ef5f24a4197d827e90a1ef9df
Autor:
Irina A. Ishina, Inna N. Kurbatskaia, Azad E. Mamedov, Elena I. Shramova, Sergey M. Deyev, Kamila S. Nurbaeva, Yury P. Rubtsov, Alexey A. Belogurov, Alexander G. Gabibov, Maria Y. Zakharova
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)
The identification of low-frequency antigen-specific CD4+ T cells is crucial for effective immunomonitoring across various diseases. However, this task still encounters experimental challenges necessitating the implementation of enrichment procedures
Externí odkaz:
https://doaj.org/article/a129dec8781a47c7902bb97ebee31679
Autor:
Chia-Hung Chen, Tzu-Han Weng, Hsiao-Hsuan Huang, Ling-Ya Huang, Kai-Yao Huang, Pin-Rong Chen, Kuang-Yu Yeh, Chi-Ting Huang, Yu-Tzu Chien, Po-Ya Chuang, Yu-Ling Lin, Nu-Man Tsai, Shih-Jen Liu, Yu-Cheng Su, Shun-Long Weng, Kuang-Wen Liao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract Background The applicability and therapeutic efficacy of specific personalized immunotherapy for cancer patients is limited by the genetic diversity of the host or the tumor. Side-effects such as immune-related adverse events (IRAEs) derived
Externí odkaz:
https://doaj.org/article/7fa82670a9fe4535a1b2aef14a40a44d
Autor:
Theerawat Dobutr, Nisachon Jangpromma, Rina Patramanon, Jureerut Daduang, Sompong Klaynongsruang, Saowanee Poopornchai, Tomio Yabe, Sakda Daduang
Publikováno v:
Biochemistry and Biophysics Reports, Vol 35, Iss , Pp 101534- (2023)
The glutinous nest that builds by the saliva secretion of swiftlet is recognizable as an edible bird's nest (EBN). It enriched a medicinal value and was regarded as supplementary food that exerts various beneficial health effects, especially immune b
Externí odkaz:
https://doaj.org/article/06009f96a90842c785a2331171f8d160
Autor:
Eider Moreno-Cortes, Pedro Franco-Fuquen, Juan E. Garcia-Robledo, Jose Forero, Natalie Booth, Januario E. Castro
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Chimeric Antigen Receptor (CAR) T-cell therapies have emerged as an effective and potentially curative immunotherapy for patients with relapsed or refractory malignancies. Treatment with CD19 CAR T-cells has shown unprecedented results in hematologic
Externí odkaz:
https://doaj.org/article/b10255e0e1874db280c7ddc7bf508fa5
Autor:
Hui Wang, Yinshi Li, Qian Yu, Mingkun Wang, Abidan Ainiwaer, Na Tang, Xuran Zheng, Adilai Duolikun, Bingqing Deng, Jing Li, Yujuan Shen, Chuanshan Zhang
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 9, Iss 5, p 95 (2024)
The cestode Echinococcus multilocularis, which mainly dwells in the liver, leads to a serious parasitic liver disease called alveolar echinococcosis (AE). Despite the increased attention drawn to the immunosuppressive microenvironment formed by hepat
Externí odkaz:
https://doaj.org/article/f79d6233bb1b4d46a057d53872730a6c
Publikováno v:
口腔疾病防治, Vol 30, Iss 7, Pp 523-527 (2022)
Oral lichen planus (OLP) is a common chronic disease of the oral mucosa with unclear pathogenesis. Local infiltration of T cells plays a key role in the pathological process of OLP. Increased evidence supports the notion that the imbalance of helper
Externí odkaz:
https://doaj.org/article/4c89015637e2455b9f90090d3aaed80b
Autor:
Jingwen Tan, Yujie Jia, Meixia Zhou, Chengcheng Fu, Israth Jahan Tuhin, Jing Ye, Masuma Akter Monty, Nan Xu, Liqing Kang, Minghao Li, Jiaqi Shao, Xiaoyan Fang, Hongjia Zhu, Lingzhi Yan, Changju Qu, Shengli Xue, Zhengming Jin, Suning Chen, Haiwen Huang, Yang Xu, Jia Chen, Miao Miao, Xiaowen Tang, Caixia Li, Zhiqiang Yan, Depei Wu, Lei Yu
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Persistence of CAR-T cell function is associated with relapse rate after CAR-T therapy, while co-stimulatory agents are highly concerned with the persistence of CAR-T cells. In this study, we designed and constructed a series of BCMA-targeti
Externí odkaz:
https://doaj.org/article/a3ee58789e894f47809e3f878bf84545